<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2954-3835</journal-id>
<journal-title><![CDATA[Cardiovascular and metabolic science]]></journal-title>
<abbrev-journal-title><![CDATA[Cardiovasc. metab. sci]]></abbrev-journal-title>
<issn>2954-3835</issn>
<publisher>
<publisher-name><![CDATA[Asociación Nacional de Cardiólogos de México A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2954-38352020000400141</article-id>
<article-id pub-id-type="doi">10.35366/97547</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[The COVID pandemic in children: an alert]]></article-title>
<article-title xml:lang="es"><![CDATA[La pandemia de COVID en niños: una alerta]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Alva Espinosa]]></surname>
<given-names><![CDATA[Carlos]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Ángeles Pedregal  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2020</year>
</pub-date>
<volume>31</volume>
<numero>4</numero>
<fpage>141</fpage>
<lpage>144</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S2954-38352020000400141&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S2954-38352020000400141&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S2954-38352020000400141&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: During the initial months of the COVID-19 pandemic, the disease was thought to be benign and infrequent in children. Since March, multisystem inflammatory syndrome (MIS-C) in children associated with the pandemic has emerged as a serious disease. It has similarities with Kawasaki disease, but also important differences, such as older age, additional abdominal symptoms, respiratory difficulties, increased severity of inflammation, heart failure, and shock. We speculate in this review: 1. If MIS-C is an accelerated form of Kawasaki disease. 2. If it is a different form. 3. Simply MIS-C is a serious variant of COVID 19 in children. The presence of the multisystem inflammatory syndrome in children associated with COVID-19 (MIS-C or PIMS-TS), in much of the world, should alert the medical community in countries where it has not yet been recognized.]]></p></abstract>
<abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: Durante los meses iniciales de la pandemia de COVID-19, se pensaba que la enfermedad en los niños era benigna y poco frecuente, a partir de marzo ha surgido el síndrome inflamatorio multisistémico (MIS-C) en niños asociado con la pandemia como una enfermedad grave. Tiene similitudes con la enfermedad de Kawasaki, aunque también importantes diferencias, como mayor edad, adicionales síntomas abdominales, escasos respiratorios, incremento en la severidad de la inflamación, falla cardiaca y choque. Especulamos en esta revisión: 1) si MIS-C es una acelerada forma de Kawasaki, 2) si se trata de una entidad diferente, o 3) simplemente MIS-C es una variante grave de COVID-19 en niños. La presencia del síndrome inflamatorio multisistémico en niños asociado con COVID-19 (MIS-C o PIMS-TS), en buena parte del mundo, debe alertar a la comunidad médica en los países en los que por el momento no se ha reconocido.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Multisystem inflammatory syndrome in children associated with COVID-19]]></kwd>
<kwd lng="en"><![CDATA[MIS-C PIMS-TS]]></kwd>
<kwd lng="en"><![CDATA[Kawasaki-like multisystem inflammatory syndrome]]></kwd>
<kwd lng="es"><![CDATA[Síndrome inflamatorio multisistémico en niños asociado con COVID-19]]></kwd>
<kwd lng="es"><![CDATA[MIS-C PIMS-TS]]></kwd>
<kwd lng="es"><![CDATA[síndrome inflamatorio multisistémico tipo Kawasaki]]></kwd>
</kwd-group>
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