<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2604-1227</journal-id>
<journal-title><![CDATA[Revista mexicana de oftalmología]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. mex. oftalmol]]></abbrev-journal-title>
<issn>2604-1227</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Mexicana de Oftalmología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2604-12272022000600259</article-id>
<article-id pub-id-type="doi">10.24875/rmo.m22000245</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Distrofia cristalina de Schnyder]]></article-title>
<article-title xml:lang="en"><![CDATA[Schnyder crystalline dystrophy]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Valdez-Payán]]></surname>
<given-names><![CDATA[Edna L.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Velasco-Ramos]]></surname>
<given-names><![CDATA[Regina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Fernández-Vizcaya]]></surname>
<given-names><![CDATA[Óscar]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Baca-Lozada]]></surname>
<given-names><![CDATA[Óscar]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Babayán-Sosa]]></surname>
<given-names><![CDATA[Alejandro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Pacheco-del-Valle]]></surname>
<given-names><![CDATA[Cristina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Alegría-Gómez]]></surname>
<given-names><![CDATA[Elisa D.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez-Reyes]]></surname>
<given-names><![CDATA[Abelardo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Fundación Hospital Nuestra Señora de la Luz Departamento de Córnea y Cirugía Refractiva ]]></institution>
<addr-line><![CDATA[ Ciudad de México]]></addr-line>
<country>México</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Dr. Luis Carlos Sánchez Bulnes Asociación para Evitar la Ceguera en México Departamento de Patología]]></institution>
<addr-line><![CDATA[ Ciudad de México]]></addr-line>
<country>México</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2022</year>
</pub-date>
<volume>96</volume>
<numero>6</numero>
<fpage>259</fpage>
<lpage>262</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S2604-12272022000600259&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S2604-12272022000600259&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S2604-12272022000600259&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Introducción: La distrofia cristalina de Schnyder es una rara distrofia corneal estromal de herencia autosómica dominante que se caracteriza por opacificación corneal bilateral y acumulación anormal de lípidos y colesterol, causada por una mutación heterocigota en el gen UBIAD1 que se encuentra en 1p36.  Caso clínico: Varón de 49 años con antecedente de pérdida visual progresiva desde la adolescencia, hipercolesterolemia y colecistectomía. A la exploración se encontraron en ambos ojos las córneas con opacidad discoidea blanco-amarillenta heterogénea en patrón reticular de bordes bien definidos, con presencia de cristales finos puntiformes policromáticos, una pequeña zona de córnea clara circundante y un arco lipídico de 360°; el área perilímbica se encontraba respetada.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Introduction: Schnyder's crystalline dystrophy is a rare autosomal dominant disease. This disorder causes a stromal dystrophy, characterized by bilateral corneal opacification, resulting from an abnormal accumulation of cholesterol and lipid. UBIAD1 is the causative gene.  Case report: A male patient aged 49 with a history of progressive visual deterioration since adolescence, hypercholesterolemia and cholecystectomy. On examination it was found both eyes with discoid heterogeneous corneal reticular opacity yellowish-white of well-defined edges with the presence of fine crystals polychromatic and a small area surrounding clear cornea and a lipid arc 360°; the perilimbic area was respected.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Colesterol]]></kwd>
<kwd lng="es"><![CDATA[Lípidos]]></kwd>
<kwd lng="es"><![CDATA[Distrofia corneal]]></kwd>
<kwd lng="es"><![CDATA[Distrofia corneal de Schnyder]]></kwd>
<kwd lng="es"><![CDATA[Distrofia corneal cristalina de Schnyder]]></kwd>
<kwd lng="en"><![CDATA[Cholesterol]]></kwd>
<kwd lng="en"><![CDATA[Lipids]]></kwd>
<kwd lng="en"><![CDATA[Corneal dystrophy]]></kwd>
<kwd lng="en"><![CDATA[Schnyder corneal dystrophy]]></kwd>
<kwd lng="en"><![CDATA[Schnyder crystalline corneal dystrophy]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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