<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2565-005X</journal-id>
<journal-title><![CDATA[Gaceta mexicana de oncología]]></journal-title>
<abbrev-journal-title><![CDATA[Gac. mex. oncol.]]></abbrev-journal-title>
<issn>2565-005X</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Mexicana de Oncología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2565-005X2022000500133</article-id>
<article-id pub-id-type="doi">10.24875/j.gamo.22000043</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Ocho neoplasias primarias metacrónicas en paciente mujer adulta mayor]]></article-title>
<article-title xml:lang="en"><![CDATA[Eight methachronical primary neoplasms in an elderly female patient]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Purizaca-Rosillo]]></surname>
<given-names><![CDATA[Nelson]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Aguilar-Villena]]></surname>
<given-names><![CDATA[Luis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Bravo-Taxa]]></surname>
<given-names><![CDATA[Mercedes]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sullcahuaman-Allende]]></surname>
<given-names><![CDATA[Yasser]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez-Espinoza]]></surname>
<given-names><![CDATA[Manuel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Falla-Jiménez]]></surname>
<given-names><![CDATA[Martín]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Nacional de Enfermedades Neoplásicas Departamento de Genética Médica ]]></institution>
<addr-line><![CDATA[Lima ]]></addr-line>
<country>Perú</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Instituto Nacional de Enfermedades Neoplásicas Departamento de Cirugía Oncológica ]]></institution>
<addr-line><![CDATA[Lima ]]></addr-line>
<country>Perú</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Instituto Nacional de Enfermedades Neoplásicas Departamento de Patología Oncológica ]]></institution>
<addr-line><![CDATA[Lima ]]></addr-line>
<country>Perú</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Instituto Nacional de Enfermedades Neoplásicas Departamento de Medicina Oncológica ]]></institution>
<addr-line><![CDATA[Lima ]]></addr-line>
<country>Perú</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2022</year>
</pub-date>
<volume>21</volume>
<fpage>133</fpage>
<lpage>136</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S2565-005X2022000500133&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S2565-005X2022000500133&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S2565-005X2022000500133&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen Las neoplasias primarias múltiples (NPM) se definen como dos o más tumores malignos primarios de diferente origen en un mismo individuo. La causa de las NPM no se ha identificado en todos los casos, sin embargo puede deberse a factores ambientales, estilos de vida y/o factores genéticos. Se presenta el caso de una paciente que ha tenido ocho neoplasias (cinco malignas y tres benignas) que han sido tratadas con éxito y que actualmente se encuentra en controles, sin evidencia de recurrencia de enfermedad o alguna otra neoplasia de novo.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Multiple primary neoplasms (MPN) are defined as 2 or more primary malignant tumors of different origin in the same individual. The cause of MPN has not been identified in all cases, however, it may be due to environmental factors, lifestyles and/or genetic factors. We present the case of a patient who has had eight neoplasms (five malignant and three benign) that have been successfully treated and who is currently undergoinf controls, with no evidence of disease recurrence or any other de novo neoplasm.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Tumores primarios múltiples]]></kwd>
<kwd lng="es"><![CDATA[Síndrome de cáncer hereditario]]></kwd>
<kwd lng="es"><![CDATA[Neoplasias metacrónicas]]></kwd>
<kwd lng="en"><![CDATA[Multiple primary neoplasms]]></kwd>
<kwd lng="en"><![CDATA[Hereditary neoplastic syndromes]]></kwd>
<kwd lng="en"><![CDATA[Metachronous neoplasms]]></kwd>
</kwd-group>
</article-meta>
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<article-title xml:lang=""><![CDATA[Analysis of polymorphisms in genes associated with the FA/BRCA pathway in three patients with multiple primary malignant neoplasms]]></article-title>
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<issue>1</issue>
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