<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2448-8909</journal-id>
<journal-title><![CDATA[Medicina crítica (Colegio Mexicano de Medicina Crítica)]]></journal-title>
<abbrev-journal-title><![CDATA[Med. crít. (Col. Mex. Med. Crít.)]]></abbrev-journal-title>
<issn>2448-8909</issn>
<publisher>
<publisher-name><![CDATA[Colegio Mexicano de Medicina Crítica A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2448-89092022000100055</article-id>
<article-id pub-id-type="doi">10.35366/104477</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Delirio, dolor, abstinencia. ¿Cuáles son las causas de las asincronías de mi enfermo con COVID-19?]]></article-title>
<article-title xml:lang="en"><![CDATA[Delirium, pain, withdrawal. What are the causes of the asynchrony of my patient with COVID-19?]]></article-title>
<article-title xml:lang="pt"><![CDATA[Delirium, dor, abstinência. Quais são as causas da assincronia do meu paciente com COVID-19?]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[García Montalvo]]></surname>
<given-names><![CDATA[Gabriel Ricardo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Tobar Galindo]]></surname>
<given-names><![CDATA[Milton Alfredo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Noboa Gallegos]]></surname>
<given-names><![CDATA[Ximena Alexandra]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Maldonado Cando]]></surname>
<given-names><![CDATA[Freddy Marcelo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital de Especialidades Carlos Andrade Marín Unidad Técnica de Adultos Área de Cuidados Intensivos]]></institution>
<addr-line><![CDATA[Quito ]]></addr-line>
<country>Ecuador</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital de Especialidades Eugenio Espejo Unidad de Cuidados Intensivos ]]></institution>
<addr-line><![CDATA[Quito ]]></addr-line>
<country>Ecuador</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>02</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>02</month>
<year>2022</year>
</pub-date>
<volume>36</volume>
<numero>1</numero>
<fpage>55</fpage>
<lpage>58</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S2448-89092022000100055&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S2448-89092022000100055&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S2448-89092022000100055&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: Los pacientes con infección por COVID-19 presentan complicaciones extrapulmonares cada vez más frecuentes, tales como trastornos neurológicos, cardiovasculares, renales, entre otros. Las asincronías, el dolor y la abstinencia a opioides mientras se encuentran en ventilación mecánica son casusas frecuentes de retardo en la liberación de soportes que acarrean otros problemas relacionados como la injuria auto infringida, infecciones, debilidad, desnutrición y muerte. Presentamos una propuesta de manejo de este tipo de enfermos.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: Patients with COVID-19 infection present more and more frequent extrapulmonary complications, such as neurological, cardiovascular, and kidney disorders, among others. Asynchronies, pain, and opioid withdrawal while on mechanical ventilation are frequent causes of delayed release of supports that lead to other related problems such as self-inflicted injury, infections, weakness, malnutrition, and death. We present a proposal for the management of this type of patient.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo: Pacientes com infecção por COVID-19 apresentam complicações extrapulmonares cada vez mais frequentes, como distúrbios neurológicos, cardiovasculares, renais, entre outros. Assincronias, dor e retirada de opióides durante a ventilação mecânica são causas frequentes de liberação tardia de suportes que levam a outros problemas relacionados, como lesões autoinfligidas, infecções, fraqueza, desnutrição e morte. Apresentamos uma proposta para a gestão deste tipo de doentes.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[SARS-CoV-2]]></kwd>
<kwd lng="es"><![CDATA[delirio]]></kwd>
<kwd lng="es"><![CDATA[dolor]]></kwd>
<kwd lng="es"><![CDATA[asincronías]]></kwd>
<kwd lng="es"><![CDATA[abstinencia]]></kwd>
<kwd lng="es"><![CDATA[COVID-19]]></kwd>
<kwd lng="en"><![CDATA[SARS-CoV-2]]></kwd>
<kwd lng="en"><![CDATA[delirium]]></kwd>
<kwd lng="en"><![CDATA[pain]]></kwd>
<kwd lng="en"><![CDATA[asynchronies]]></kwd>
<kwd lng="en"><![CDATA[abstinence]]></kwd>
<kwd lng="en"><![CDATA[COVID-19]]></kwd>
<kwd lng="pt"><![CDATA[SARS-CoV-2]]></kwd>
<kwd lng="pt"><![CDATA[delírio]]></kwd>
<kwd lng="pt"><![CDATA[dor]]></kwd>
<kwd lng="pt"><![CDATA[assincronia]]></kwd>
<kwd lng="pt"><![CDATA[abstinência]]></kwd>
<kwd lng="pt"><![CDATA[COVID-19]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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