<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2448-8909</journal-id>
<journal-title><![CDATA[Medicina crítica (Colegio Mexicano de Medicina Crítica)]]></journal-title>
<abbrev-journal-title><![CDATA[Med. crít. (Col. Mex. Med. Crít.)]]></abbrev-journal-title>
<issn>2448-8909</issn>
<publisher>
<publisher-name><![CDATA[Colegio Mexicano de Medicina Crítica A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2448-89092020000200125</article-id>
<article-id pub-id-type="doi">10.35366/93965</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Factores asociados con la mortalidad en el adulto mayor con choque séptico]]></article-title>
<article-title xml:lang="en"><![CDATA[Factors associated with mortality in the elderly adult with septic shock]]></article-title>
<article-title xml:lang="pt"><![CDATA[Fatores associados à mortalidade no idoso com choque séptico]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[González Escudero]]></surname>
<given-names><![CDATA[Eduardo Alberto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sánchez Díaz]]></surname>
<given-names><![CDATA[Jesús Salvador]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Solórzano Guerra]]></surname>
<given-names><![CDATA[Armando]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Peniche Moguel]]></surname>
<given-names><![CDATA[Karla Gabriela]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Villegas Domínguez]]></surname>
<given-names><![CDATA[Josué Eli]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Calyeca Sánchez]]></surname>
<given-names><![CDATA[María Verónica]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Mexicano del Seguro Social Centro Médico Nacional «Adolfo Ruiz Cortines» Hospital de Especialidades Núm. 14]]></institution>
<addr-line><![CDATA[Veracruz Veracruz]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad del Valle de México Facultad de Medicina ]]></institution>
<addr-line><![CDATA[Veracruz ]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>04</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>04</month>
<year>2020</year>
</pub-date>
<volume>34</volume>
<numero>2</numero>
<fpage>125</fpage>
<lpage>132</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S2448-89092020000200125&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S2448-89092020000200125&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S2448-89092020000200125&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen:  Introducción:  Se estima que para el año 2050, a nivel mundial y por primera vez en la historia, la población anciana será mayor que la población joven. Con respecto a este grupo de edad, se calcula que la incidencia de choque séptico es 13 veces más común en los pacientes mayores de 65 años, por lo que conocer los factores de riesgo asociados con mortalidad en esta población es indispensable para la terapéutica.  Material y métodos:  Estudio ambispectivo, longitudinal, descriptivo y analítico en el que se incluyeron a pacientes con diagnóstico de choque séptico según el consenso Sepsis-3 ingresados a la Unidad de Cuidados Intensivos del primero de junio de 2015 al 31 de junio de 2019. Se clasificaron los grupos en: &lt; 65 y &gt; 65 años, y se incluyeron variables demográficas, hemodinámicas (índice de choque modificado, SvcO2, &#916;p (v-a) CO2 /&#916;p (a-v) O2, BNP, vasopresor), respiratorias (PaO2 /FiO2), metabólicas (pH, HCO3- DB) y renales, para compararlas entre ambos grupos. El grupo &gt; 65 años se subclasificó de acuerdo con el desenlace en vivos y no vivos, para identificar a las variables con valor estadístico para el mismo; se utilizó estadística descriptiva, &#967;2 y prueba exacta de Fisher y t de Student y U de Mann-Whitney de acuerdo con el caso. Se consideró significancia un valor de p &#8804; 0.05 y se empleó el programa SPSS en su versión 20.  Resultados:  Un total de 118 pacientes cumplieron con los criterios de inclusión. De ellos, 78 pacientes se designaron al grupo &lt; 65 años y 40 pacientes al grupo &gt; 65 años. La mortalidad en el grupo &gt; 65 años fue de 67.5% en comparación con 36% en el grupo &lt; 65 años; con p = 0.001. En el grupo &gt; 65 años, 27 pacientes fallecieron. Las variables hemodinámicas y respiratorias no tuvieron significancia estadística, a diferencia del pH (p = 0.037), base (p = 0.041) y norepinefrina (p = 0.03).  Conclusión:  Los pacientes &gt; 65 años de edad tienen una mayor gravedad y comorbilidad respecto a los pacientes más jóvenes. Las variables hemodinámicas y respiratorias no influyen en el desenlace; la acidosis metabólica grave es un factor de riesgo para mortalidad en los pacientes &gt; 65 años.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract:  Introduction:  By 2050 the elderly population worldwide for the first time in history will be greater than the young population. The incidence of septic shock is 13 times more common in patients &gt; 65 years, knowing the risk factors associated with mortality in this population is essential for therapeutics.  Material and methods:  Ambispective, longitudinal, descriptive, analytical study. Patients with a diagnosis of septic shock according to the consensus Sepsis-3 admitted to the ICU from June 1, 2015 to June 31, 2019. They were classified in the groups: 65 years, demographic, hemodynamic variables were included (index modified shock, SvcO2, &#916;p (va) CO2 /&#916;p (av) O2, BNP, vasopressor), respiratory (PaO2 /FiO2), metabolic (pH, HCO3- DB) and renal to compare them between both groups; the group &gt; 65 years was subclassified according to the outcome in living and non-living to identify the variables with statistical value for it; descriptive statistics, &#967;2 and exact test of Fisher and t-Student and U-Mann-Whitney were used according to the case. A value of p &#8804; 0.05 was considered significance and the program was used SPSS in version 20.  Results:  118 patients met the inclusion criteria. 78 patients in the group 65 years. Mortality in &gt; 65 years was 67.5% versus 36% in 65 years, 27 patients died. The hemodynamic and respiratory variables had no statistical significance; unlike pH (p = 0.037), base (p = 0.041) and norepinephrine (p = 0.03).  Conclusion:  Patients &gt; 65 years of age have greater severity and comorbidity compared to younger patients. The hemodynamic and respiratory variables do not influence the outcome; severe metabolic acidosis is a risk factor for mortality in patients &gt; 65 years.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo:  Introdução:  Até 2050, a população idosa em todo o mundo pela primeira vez na história será maior que a população jovem. A incidência de choque séptico é 13 vezes mais comum em pacientes &gt; 65 anos, sabendo que os fatores de risco associados à mortalidade nessa população são essenciais para a terapêutica.  Material e métodos:  Estudo ambispectico, longitudinal, descritivo e analítico. Pacientes com diagnóstico de choque séptico segundo o consenso Sepsis-3 admitidos na UTI de 1o de junho de 2015 a 31 de junho de 2019. Eles foram classificados nos grupos: &lt; 65 e &gt; 65 anos. Foram incluídas variáveis demográficas, hemodinâmicas (índice de choque modificado, SvcO2, &#916;p (v-a) CO2 /&#916;p (a-v) O2, BNP, vasopressor), respiratórios (PaO2 /FiO2), metabólicos (pH, HCO3-DB) e renais para compará-los entre os dois grupos; o grupo &gt; 65 anos foi subclassificado de acordo com o desfecho em sobreviver e não sobreviver para identificar as variáveis com valor estatístico para ele. Foram utilizados estatística descritiva, &#967;2 e teste exato de Fisher e T-Student e U-Mann-Whitney de acordo com o caso. Um valor de p &#8804; 0.05 foi considerado significativo, foi utilizado o SPPSS20.  Resultados:  118 pacientes preencheram os critérios de inclusão. 78 pacientes no grupo &lt; 65 anos e 40 pacientes no grupo &gt; 65 anos. A mortalidade em &gt; 65 anos foi de 67.5% versus 36% em &lt; 65 anos com p = 0.001. No grupo &gt; 65 anos, 27 pacientes morreram. As variáveis hemodinâmicas e respiratórias não apresentaram significância estatística; diferentemente do pH (p = 0.037), base (p = 0.041) e noradrenalina (p = 0.03).  Conclusão:  Pacientes com idade &gt; 65 anos apresentam maior gravidade e comorbidade que pacientes mais jovens. As variáveis hemodinâmicas e respiratórias não influenciam o resultado; A acidose metabólica grave é um fator de risco para mortalidade em pacientes &gt; 65 anos.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Choque séptico]]></kwd>
<kwd lng="es"><![CDATA[factores de riesgo]]></kwd>
<kwd lng="es"><![CDATA[mortalidad]]></kwd>
<kwd lng="en"><![CDATA[Septic shock]]></kwd>
<kwd lng="en"><![CDATA[risk factors]]></kwd>
<kwd lng="en"><![CDATA[mortality]]></kwd>
<kwd lng="pt"><![CDATA[Choque séptico]]></kwd>
<kwd lng="pt"><![CDATA[fatores de risco]]></kwd>
<kwd lng="pt"><![CDATA[mortalidade]]></kwd>
</kwd-group>
</article-meta>
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