<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2448-8909</journal-id>
<journal-title><![CDATA[Medicina crítica (Colegio Mexicano de Medicina Crítica)]]></journal-title>
<abbrev-journal-title><![CDATA[Med. crít. (Col. Mex. Med. Crít.)]]></abbrev-journal-title>
<issn>2448-8909</issn>
<publisher>
<publisher-name><![CDATA[Colegio Mexicano de Medicina Crítica A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2448-89092019000200066</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Delta de cloro (&#916;Cl-) sérico como pronóstico de mortalidad en pacientes con choque séptico]]></article-title>
<article-title xml:lang="en"><![CDATA[Chloride delta (&#916;Cl-) serum as a prognosis of mortality in patients with septic shock]]></article-title>
<article-title xml:lang="pt"><![CDATA[Delta cloro (&#916;Cl - ) sérico como prognóstico de mortalidade em pacientes com choque séptico]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Martínez Rojas]]></surname>
<given-names><![CDATA[Manuel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sánchez Díaz]]></surname>
<given-names><![CDATA[Jesús Salvador]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Peniche Moguel]]></surname>
<given-names><![CDATA[Karla Gabriela]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Martínez Rodríguez]]></surname>
<given-names><![CDATA[Enrique Antonio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gutiérrez Jiménez]]></surname>
<given-names><![CDATA[Ángel Armando]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Calyeca Sánchez]]></surname>
<given-names><![CDATA[María Verónica]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Mexicano del Seguro Social Hospital de Especialidades No. 14 Unidad Médica de Alta Especialidad 189]]></institution>
<addr-line><![CDATA[Veracruz ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Centro Médico ABC  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>04</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>04</month>
<year>2019</year>
</pub-date>
<volume>33</volume>
<numero>2</numero>
<fpage>66</fpage>
<lpage>72</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S2448-89092019000200066&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S2448-89092019000200066&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S2448-89092019000200066&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen:  Introducción:  La reanimación con cristaloides intravenosos para restaurar el volumen circulatorio en pacientes con choque séptico es fundamental para el tratamiento a nivel mundial, la solución salina al 0.9% (SS0.9%) es el cristaloide más utilizado. La hipercloremia en la mayoría de los pacientes es iatrogénica y pude evitarse.  Material y métodos:  Se realizó un estudio de cohorte, ambispectivo, observacional, analítico y longitudinal. Se incluyeron pacientes mayores de 18 años que ingresaron a la Unidad de Cuidados Intensivos (UCI) con el diagnóstico de choque séptico según las Guías de la Campaña Sobreviviendo a la Sepsis del año 2016, en el periodo de tiempo comprendido del 15 de junio del 2015 al 30 de octubre del 2017. Se realizó el análisis con estadística descriptiva, &#967;2 y t Student para variables de distribución normal y prueba exacta de Fisher y U-Mann Whitney para variables no paramétricas. Todos los análisis estadísticos se realizaron con el programa PSSW SPSSTM 22.0.  Resultados:  En el periodo considerado, 70 pacientes cumplieron con los criterios de selección planteados, de los cuales 32 (45.7%) fallecieron y 38 (54.3%) sobrevivieron. Del total de pacientes, 35 (50%) fueron mujeres. El abdomen fue el foco de infección más frecuente con 44.3%, seguido por el pulmonar en 25.7%. El servicio de procedencia más común fue Urgencias con 38.6% del total de pacientes ingresados.  Conclusión:  El &#916;Cl - medido después de 24 horas con punto de corte &#8805; 4 mEq/L es un factor de riesgo para la mortalidad en los pacientes con choque séptico, la probabilidad de supervivencia acumulada al día 30 es de 38%.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract:  Introduction:  Resuscitation with intravenous crystalloids to restore circulatory volume in patients with septic shock is fundamental for the treatment. Worldwide, saline solution 0.9% (SS0.9%) is the most widely used crystalloid. Hyperchloremia in most patients is iatrogenic and could be avoided.  Material and methods:  A cohort, ambispective, observational, analytical and longitudinal study was carried. We included patients older than 18 years admitted to the Intensive Care Unit (ICU) with the diagnosis of septic shock according to the Guidelines of the Campaign Surviving the Sepsis of 2016, in the period from June 15, 2015 to October 30, 2017. The analysis was performed with descriptive statistics, &#967;2 and t-Student for variables of normal distribution and Fisher&#8217;s exact test and U-Mann Whitney for nonparametric variables. All statistical analyzes were performed with the PSSW SPSSTM 22.0 program.  Results:  In the period considered, 70 patients fulfilled the selection criteria proposed, of which 32 (45.7%) died and 38 (54.3%) survived. Of the total patients, thirty-five (50%) were women. The abdomen was the most frequent source of infection with 44.3%, followed by the lung in 25.7%. The most common service was Urgencies with 38.6% of the total number of patients admitted.  Conclusion:  The &#916;Cl  - measured at 24 hours with cut point  &#8805; 4 mEq/L is a risk factor for mortality in patients with septic shock, the probability of cumulative survival at day 30 is 38%.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo:  Introdução:  A ressuscitação com cristaloides intravenosos para restaurar o volume circulatório em pacientes com choque séptico é fundamental para o tratamento. A nível mundial a solução salina a 0.9% (SS 0.9%) é o cristalóide mais utilizado. A hipercloremia na maioria dos pacientes é iatrogênica e pode ser evitada.  Material e métodos:  Estudo de coorte, ambispectivo, observacional, analítico e longitudinal. Foram incluídos pacientes com idade superior a 18 anos que foram admitidos na Unidade de Terapia Intensiva (UTI) com diagnóstico de choque séptico de acordo com as diretrizes da campanha que sobrevivendo à sepse de 2016, entre 15 de junho de 2015 e 30 de outubro de 2017. A análise foi realizada com estatística descritiva, &#967;2 e T-Student para variáveis de distribuição normal e teste exato de Fisher e U-Mann Whitney para variáveis não paramétricas. Todas as análises estatísticas foram realizadas com o programa PSSW SPSSTM 22.0.  Resultados:  No período considerado, 70 pacientes preencheram os critérios de seleção propostos, dos quais 32 (45.7%) foram a óbito e 38 (54.3%) sobreviveram. Do total de pacientes, trinta e cinco (50%) eram mulheres. O abdome foi a fonte mais frequente de infecção com 44.3%, seguido do pulmão em 25.7%. O serviço mais comum foi Urgências com 38.6% do total de pacientes internados.  Conclusão:  O &#916;Cl - medido em 24 h com ponto de corte &#8805; 4 mE/L é um fator de risco para mortalidade em pacientes com choque séptico e a probabilidade de sobrevida acumulada ao dia 30 é de 38%.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Choque séptico]]></kwd>
<kwd lng="es"><![CDATA[solución salina 0.9%]]></kwd>
<kwd lng="es"><![CDATA[delta de cloro]]></kwd>
<kwd lng="es"><![CDATA[mortalidad]]></kwd>
<kwd lng="en"><![CDATA[Septic shock]]></kwd>
<kwd lng="en"><![CDATA[saline solution 0.9%]]></kwd>
<kwd lng="en"><![CDATA[chloride delta]]></kwd>
<kwd lng="en"><![CDATA[mortality]]></kwd>
<kwd lng="pt"><![CDATA[Choque séptico]]></kwd>
<kwd lng="pt"><![CDATA[solução salina a 0.9%]]></kwd>
<kwd lng="pt"><![CDATA[delta de cloro]]></kwd>
<kwd lng="pt"><![CDATA[mortalidade]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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