<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2448-8909</journal-id>
<journal-title><![CDATA[Medicina crítica (Colegio Mexicano de Medicina Crítica)]]></journal-title>
<abbrev-journal-title><![CDATA[Med. crít. (Col. Mex. Med. Crít.)]]></abbrev-journal-title>
<issn>2448-8909</issn>
<publisher>
<publisher-name><![CDATA[Colegio Mexicano de Medicina Crítica A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2448-89092016000500283</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Clasificación clínica de la perfusión tisular en pacientes con choque séptico basada en la saturación venosa central de oxígeno (SvcO 2 ) y la diferencia venoarterial de dióxido de carbono entre el contenido arteriovenoso de oxígeno (&#916;P(v-a)CO 2 /C(a-v)O 2 )]]></article-title>
<article-title xml:lang="en"><![CDATA[Clinical classification of tissue perfusion in patients with septic shock based on central venous oxygen saturation (SvcO 2 ) and central venous-to-arterial carbon dioxide difference/arterial-central venous oxygen (&#916;P(v-a)CO 2 /C(a-v)O 2 )]]></article-title>
<article-title xml:lang="pt"><![CDATA[Classificação clínica da perfusão tecidual em pacientes com choque séptico baseada na saturação venosa central de oxigênio (SvcO 2 ) e a diferença venoarterial de dióxido de carbono entre o conteúdo artério-venoso de oxigênio (&#916;P(v-a)CO 2 /C(a-v)O 2 )]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rivera Solís]]></surname>
<given-names><![CDATA[Gerardo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sánchez Díaz]]></surname>
<given-names><![CDATA[Jesús Salvador]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Martínez Rodríguez]]></surname>
<given-names><![CDATA[Enrique Antonio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[García Méndez]]></surname>
<given-names><![CDATA[Rosalba Carolina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Huanca Pacaje]]></surname>
<given-names><![CDATA[Juan Marcelo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Calyeca Sánchez]]></surname>
<given-names><![CDATA[María Verónica]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Mexicano del Seguro Social (IMSS) Hospital de Especialidades Núm. 14 ]]></institution>
<addr-line><![CDATA[Veracruz Veracruz]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Veracruzana Facultad de Medicina Campus Veracruz]]></institution>
<addr-line><![CDATA[Veracruz ]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2016</year>
</pub-date>
<volume>30</volume>
<numero>5</numero>
<fpage>283</fpage>
<lpage>289</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S2448-89092016000500283&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S2448-89092016000500283&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S2448-89092016000500283&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen:  Introducción:  El choque séptico es la principal causa de choque en la unidad de cuidados intensivos (62% de todos los casos), su mortalidad es alrededor de 40 a 50%; el reconocimiento temprano de la hipoperfusión tisular es vital para su manejo.  Material y métodos:  Estudio de cohorte prospectivo, longitudinal, descriptivo y analítico. Se incluyeron pacientes con diagnóstico de choque séptico según las guías de la Campaña Sobreviviendo a la Sepsis del año 2012 ingresados en la unidad de cuidados intensivos en el periodo que comprende de junio de 2015 a junio de 2016.  Resultados:  El análisis multivariado de supervivencia a las 24 horas mostró que la SvcO2 &gt; 70% tuvo un OR 0.23 (IC95% 0.047-1.15) p = 0.075 y la (&#916;P (v-a)CO2/C(a-v)O2) &gt;1.4 tuvo un OR 5.49 (IC95% 1.07-28.09) p = 0.04. El grupo 4 (SvcO2 &lt; 70% y (&#916;P (v-a)CO2/C(a-v)O2)&gt;1.4), que incluyó a siete pacientes, fue el de peor pronóstico, con 43% de mortalidad (n = 6).  Discusión:  Diferentes estudios han demostrado que es pobre la correlación entre la macro- y la microcirculación, que las alteraciones microcirculatorias están presentes antes del descenso de la presión arterial, del gasto cardiaco, y que la densidad de vasos perfundidos es independiente de estos parámetros.  Conclusión:  Los pacientes con choque séptico que tienen SvcO2 &lt;70% y &#916;P(v-a)CO2/C(a-v)O2 &gt;1.4 medidos a las 24 horas de ingreso presentan mayor mortalidad a 30 días.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract:  Introduction:  Septic shock is the leading cause of shock in the intensive care unit (62% of all cases), mortality is about 40 to 50%; early recognition of tissue hypoperfusion is vital for management.  Material and methods:  A prospective, longitudinal, descriptive and analytical cohort study, which included patients diagnosed with septic shock according to the guidelines of the Surviving Sepsis Campaign in 2012 admitted to the intensive care unit during the period comprising from June 2015 to June 2016.  Results:  Multivariate analysis of survival at 24 hours showed that SvcO2 &gt;70%, OR 0.23 (CI95% 0.047-1.15) p=0.07 and (&#916;P(v-a)CO2/C(a-v)O2) &gt;1.4, OR 5.49 (CI95% 1.07-28.09) p = 0.04. The Group 4 (ScvO2 &lt;70% and (&#916;P(v-a)CO2/C(a-v)O2)&gt;1.4), which included seven patients, was associated with poor prognosis and 43% mortality (n = 6).  Discussion:  Different studies have shown poor correlation between macro- and microcirculation, that microcirculatory alterations are present before the drop in blood pressure, cardiac output, and that perfused vessel density is independent of these parameters.  Conclusion:  Patients with septic shock with SvcO2&lt;70% and (&#916;P(v-a)CO2/C(a-v)O2) &gt;1.4 measured at 24 hours of admission have increased 30-day mortality.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[Resumo:  Introdução:  O choque séptico é a principal causa de choque na unidade de terapia intensiva (62% de todos os casos), a mortalidade é de cerca de 40 a 50% e o reconhecimento precoce de hipoperfusão tecidual é vital para o tratamento.  Material e métodos:  Estudo prospectivo, longitudinal, descritivo e de coorte analítico. Os pacientes com diagnóstico de choque séptico, de acordo com as guias da campanha Sobrevivendo a Sepsis do ano 2012, internados na unidade de terapia intensiva, no período compreendido entre junho de 2015 a junho de 2016.  Resultados:  A análise de sobrevivência multivariada de 24 horas mostrou que a SvcO2 &gt; 70% obteve um OR 0.23 (IC95% 0.047-1.15) p = 0.075 e a (&#916;P(v-a)CO2/C(a-v)O2) &gt; 1.4 obteve um OR 5.49 (IC95% 1.07-28.09) p = 0.04. O Grupo 4 (SvcO2 &lt; 70% y (&#916;P(v-a)CO2/C(a-v)O2) &gt; 1.4) que incluiu 7 pacientes, foi o pior prognóstico com 43% de mortalidade (n = 6).  Discussão:  Vários estudos demonstraram uma correlação deficiente entre a macro e microcirculação, que as alterações microcirculatórias estão presentes antes da queda da pressão arterial, do déficit cardíaco e que a densidade dos vasos perfundidos é independente destes parâmetros.  Conclusão:  Os pacientes com choque séptico que apresentaram SvcO2 &lt;70% e &#916;P(v-a)CO2/C(a-v)O2 &gt;1.4 medido as 24 horas da admissão, apresentaram um aumento da mortalidade em 30 dias.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Unidad de cuidados intensivos]]></kwd>
<kwd lng="es"><![CDATA[choque séptico]]></kwd>
<kwd lng="es"><![CDATA[hipoperfusión]]></kwd>
<kwd lng="es"><![CDATA[mortalidad]]></kwd>
<kwd lng="en"><![CDATA[Intensive care unit]]></kwd>
<kwd lng="en"><![CDATA[septic shock]]></kwd>
<kwd lng="en"><![CDATA[hypoperfusion]]></kwd>
<kwd lng="en"><![CDATA[mortality]]></kwd>
<kwd lng="pt"><![CDATA[Unidade de terapia intensiva]]></kwd>
<kwd lng="pt"><![CDATA[choque séptico]]></kwd>
<kwd lng="pt"><![CDATA[hipoperfusão]]></kwd>
<kwd lng="pt"><![CDATA[mortalidade]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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