<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2448-8909</journal-id>
<journal-title><![CDATA[Medicina crítica (Colegio Mexicano de Medicina Crítica)]]></journal-title>
<abbrev-journal-title><![CDATA[Med. crít. (Col. Mex. Med. Crít.)]]></abbrev-journal-title>
<issn>2448-8909</issn>
<publisher>
<publisher-name><![CDATA[Colegio Mexicano de Medicina Crítica A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2448-89092016000200087</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Utilidad del volumen plaquetario medio para descartar sepsis]]></article-title>
<article-title xml:lang="en"><![CDATA[Mean platelet volume to rule out sepsis]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sánchez Calzada]]></surname>
<given-names><![CDATA[Armando]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Navarro Adame]]></surname>
<given-names><![CDATA[José Luis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Delgado Ayala]]></surname>
<given-names><![CDATA[Lucía Yunuem]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Torres Aguilar]]></surname>
<given-names><![CDATA[Óscar]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Franco Granillo]]></surname>
<given-names><![CDATA[Juvenal]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Aguirre Sánchez]]></surname>
<given-names><![CDATA[Janet]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Camarena Alejo]]></surname>
<given-names><![CDATA[Gilberto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Monares Zepeda]]></surname>
<given-names><![CDATA[Enrique]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Torres Gómez]]></surname>
<given-names><![CDATA[Armando]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Centro Médico ABC  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2016</year>
</pub-date>
<volume>30</volume>
<numero>2</numero>
<fpage>87</fpage>
<lpage>94</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S2448-89092016000200087&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S2448-89092016000200087&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S2448-89092016000200087&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: La sepsis es uno de los principales diagnósticos de ingreso en las unidades de terapia intensiva; se ha demostrado que el inicio del tratamiento oportuno reduce significativamente la mortalidad. El volumen plaquetario medio (VPM) se ve afectado en cuadros clínicos inflamatorios; el grado de inflamación y los cambios en el VPM parecen estar correlacionados.  Objetivo: Utilizar la determinación de VPM como marcador de infección bacteriana.  Material y métodos: Estudio prospectivo, longitudinal, descriptivo, observacional; se valoraron todos los pacientes ingresados a la unidad de cuidados intensivos del Centro Médico ABC; Grupo 1: individuos con diagnóstico de sepsis; Grupo 2: sujetos sin sepsis.  Resultados: Se encontró una elevación del VPM por arriba de 7.4 fL en el grupo de sepsis (p &lt; 0.001), con mejor determinación a las 72 horas (p &lt; 0.001). En el grupo de personas sin sepsis, el VPM permaneció bajo (p &lt; 0.012).  Conclusiones: El VPM puede ser utilizado como marcador de infección bacteriana en centros donde no se cuente con marcadores como la procalcitonina. En centros médicos donde se cuente con la determinación de procalcitonina, se puede incrementar la sensibilidad, así como la especificidad del diagnóstico de sepsis bacteriana, con el uso del VPM. El VPM es un marcador de infección bacteriana de fácil acceso y bajo costo.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: Sepsis is one of the main causes of admission to the intensive care unit, and a prompt treatment reduces mortality significantly. Inflammatory diseases, including sepsis, affect the mean platelet volume (MPV); the level appears to be correlated with the degree of inflammation.  Objective:  To determine the utility of MPV as a marker of bacterial infection.  Material and methods: A prospective, longitudinal, descriptive, observational study. All patients admitted to the ABC Medical Center intensive care unit were included. Group 1: individuals diagnosed with sepsis; Group 2: those without sepsis.  Results: MPV elevation was found above 7.4 fL in the sepsis group (p &lt; 0.001), with better determination at 72 hours (p &lt; 0.001). The VPM remained low in the group of patients without sepsis (p &lt; 0.012).  Conclusions:  The VPM can be used as a marker of bacterial infection in centers where there are no such markers as procalcitonin. Medical centers that have the tools to measure procalcitonin can increase their sensitivity and specificity of diagnosis of bacterial sepsis with the use of VPM. The VPM is an inexpensive and easily accessible marker of bacterial infection.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Volumen plaquetario medio]]></kwd>
<kwd lng="es"><![CDATA[sepsis]]></kwd>
<kwd lng="es"><![CDATA[marcador de infección bacteriana]]></kwd>
<kwd lng="en"><![CDATA[Mean platelet volume]]></kwd>
<kwd lng="en"><![CDATA[sepsis]]></kwd>
<kwd lng="en"><![CDATA[bacterial infection marker]]></kwd>
</kwd-group>
</article-meta>
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