2007-5057 2007-5057 S2007-50572018000400112 10.22201/facmed.20075057e.2018.28.18116 Colombia Paraguay Ecuador 00 12 2018 00 12 2018 7 28 112 113 1 2010 34 7 7 1406-15 2 OMS 1993 3 2017 23 1 1 52-9