<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2007-3380</journal-id>
<journal-title><![CDATA[Revista bio ciencias]]></journal-title>
<abbrev-journal-title><![CDATA[Revista bio ciencias]]></abbrev-journal-title>
<issn>2007-3380</issn>
<publisher>
<publisher-name><![CDATA[Universidad Autónoma de Nayarit]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2007-33802019000200205</article-id>
<article-id pub-id-type="doi">10.15741/revbio.06.nesp.e670</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[In Vitro Antimicrobial Activity of Methanolic and Hexanic Extracts of Turnera diffusa Against Common Urinary Pathogens]]></article-title>
<article-title xml:lang="es"><![CDATA[Actividad Antimicrobiana in vitro de extractos metánolicos y hexánicos de Turnera diffusa contra patógenos comunes de vías urinarias]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Báez-Parra]]></surname>
<given-names><![CDATA[K. M.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Soto-Beltrán]]></surname>
<given-names><![CDATA[M.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[López-Cuevas]]></surname>
<given-names><![CDATA[O.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Basilio Heredia]]></surname>
<given-names><![CDATA[J.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Alcaraz-Meléndez]]></surname>
<given-names><![CDATA[L.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Angulo-Escalante]]></surname>
<given-names><![CDATA[M. A.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Centro de Investigación en Alimentación y Desarrollo, A.C.  ]]></institution>
<addr-line><![CDATA[Culiacán Sinaloa]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Autónoma de Sinaloa  ]]></institution>
<addr-line><![CDATA[Culiacán Sinaloa]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Centro de Investigaciones Biológicas del Noroeste  ]]></institution>
<addr-line><![CDATA[La Paz Baja California Sur]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2019</year>
</pub-date>
<volume>6</volume>
<numero>spe</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S2007-33802019000200205&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S2007-33802019000200205&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S2007-33802019000200205&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Turnera diffusa Willd. ex Schult. is well known in traditional medicine as aphrodisiac, diuretic, hypoglycemic, tranquilizer and urinary tract antiseptic, here the main focus was the antiseptic effect. The goal of this study was to evaluate the antimicrobial activity of methanolic and hexanic extracts of two varieties of Turnera diffusa Willd. ex Schult against main tract urinary pathogens. Also, the chromatographic profile of the extracts was generated. For the methanolic extract the mobile phase was composed of ethyl acetate, acetic and formic acids and water (100:11:11:27). On the other hand, hexane and acetic acid (7.2:2.9) were used for the hexanic extract. The antimicrobial activity and minimum inhibition concentration were evaluated by the disc diffusion method and microdilution method, respectively, against Klebsiella pneumoniae, Enterococcus faeccalis, Staphylococcus aureus, Escherichia coli and Candida albicans. The methanolic extract revealed the presence of bands from yellow to orange while the hexanic extract showed bands from blue to violet. The results showed antibacterial and antifungal activities of both methanolic and hexanic extracts of Turnera diffusa var. diffusa and Turnera diffusa var. aphrodisiaca against urinary tract pathogenic species, confirming one of their potential medicinal uses.]]></p></abstract>
<abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen Turnera diffusa Willd. ex Schult, es conocida en la medicina tradicional como afrodisíaco, diurético, hipoglucémico, tranquilizante y antiséptico del tracto urinario, en este trabajo nos centramos en el efecto antiséptico; por lo que el objetivo de este estudio fue evaluar la actividad antimicrobiana de los extractos metanólicos y hexánicos de dos variedades de Turnera diffusa Willd. ex Schult contra los principales patógenos urinarios. Además se generaron perfiles cromatográficos de los extractos, donde, se utilizó para el extracto metanólico, la fase móvil compuesta de acetato de etilo, ácido acético, ácido fórmico y agua (100:11:11:27). Por otro lado, se utilizaron hexano y ácido acético (7.2:2.9) para el extracto hexánico. La actividad antimicrobiana y la concentración mínima inhibitoria se evaluaron mediante el método de difusión en disco y microdilución, respectivamente, contra Klebsiella pneumoniae, Enterococcus faeccalis, Staphylococcus aureus, Escherichia coli y Candida albicans. El extracto metanólico reveló la presencia de bandas de amarillo a naranja, mientras que el extracto hexánico mostró bandas de azul a violeta. Los resultados mostraron actividades antibacterianas y antifúngicas de los extractos metanólicos y hexánicos de las variedades Turnera diffusa var. diffusa y Turnera diffusa var. aphrodisiaca contra especies patógenas del tracto urinario, confirmando uno de sus usos medicinales.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Antimicrobial activity]]></kwd>
<kwd lng="en"><![CDATA[HPTLC (High performance thin layer chromatography)]]></kwd>
<kwd lng="en"><![CDATA[minimum inhibitory concentration (MIC)]]></kwd>
<kwd lng="en"><![CDATA[Turnera diffusa]]></kwd>
<kwd lng="en"><![CDATA[urinary tract infections]]></kwd>
<kwd lng="es"><![CDATA[Actividad antimicrobiana]]></kwd>
<kwd lng="es"><![CDATA[HPTLC (cromatografía en capa fina de alta resolución)]]></kwd>
<kwd lng="es"><![CDATA[concentración inhibitoria mínima (MIC)]]></kwd>
<kwd lng="es"><![CDATA[Turnera diffusa]]></kwd>
<kwd lng="es"><![CDATA[infecciones del tracto urinario]]></kwd>
</kwd-group>
</article-meta>
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