<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2007-3364</journal-id>
<journal-title><![CDATA[Therya]]></journal-title>
<abbrev-journal-title><![CDATA[Therya]]></abbrev-journal-title>
<issn>2007-3364</issn>
<publisher>
<publisher-name><![CDATA[Asociación Mexicana de Mastozoología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2007-33642025000100125</article-id>
<article-id pub-id-type="doi">10.12933/therya-25-6154</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Wildlife disease surveillance from village to peak: Trypanosome infections of mammals on Sulawesi revealed higher prevalence in intact montane forests]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Adams]]></surname>
<given-names><![CDATA[Amy L.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Achmadi]]></surname>
<given-names><![CDATA[Anang S.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mursyid]]></surname>
<given-names><![CDATA[Ahmad]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Handika]]></surname>
<given-names><![CDATA[Heru]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Nurdin]]></surname>
<given-names><![CDATA[M. Rizaldi T.J.P.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Esselstyn]]></surname>
<given-names><![CDATA[Jacob A.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Perkins]]></surname>
<given-names><![CDATA[Susan L.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rowe]]></surname>
<given-names><![CDATA[Karen M.C.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rowe]]></surname>
<given-names><![CDATA[Kevin C.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Museums Victoria Research Institute Sciences Department ]]></institution>
<addr-line><![CDATA[Melbourne Victoria]]></addr-line>
<country>Australia</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Research Center for Biosystematics and Evolution, Baden Riset dan Innovasi Nasional Museum Zoologicum Bogoriense ]]></institution>
<addr-line><![CDATA[ Cibinong]]></addr-line>
<country>Indonesia</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,The Indonesian Society for Bioinformatics and Biodiversity  ]]></institution>
<addr-line><![CDATA[Malang ]]></addr-line>
<country>Indonesia</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Louisiana State University Museum of Natural Science ]]></institution>
<addr-line><![CDATA[Baton Rouge Louisiana]]></addr-line>
<country>USA</country>
</aff>
<aff id="Af5">
<institution><![CDATA[,Louisiana State University Department of Biological Sciences ]]></institution>
<addr-line><![CDATA[Baton Rouge Louisiana]]></addr-line>
<country>USA</country>
</aff>
<aff id="Af6">
<institution><![CDATA[,Universitas Sulawesi Barat Department of Biological Education ]]></institution>
<addr-line><![CDATA[Majene West Sulawesi]]></addr-line>
<country>Indonesia</country>
</aff>
<aff id="Af7">
<institution><![CDATA[,The City College of New York Department of Biology ]]></institution>
<addr-line><![CDATA[New York ]]></addr-line>
<country>USA</country>
</aff>
<aff id="Af8">
<institution><![CDATA[,The University of Melbourne School of Biosciences ]]></institution>
<addr-line><![CDATA[Parkville Victoria]]></addr-line>
<country>Australia</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2025</year>
</pub-date>
<volume>16</volume>
<numero>1</numero>
<fpage>125</fpage>
<lpage>141</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S2007-33642025000100125&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S2007-33642025000100125&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S2007-33642025000100125&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Zoonotic diseases, including those carried by mammalian hosts, pose a significant threat to human health worldwide and substantial investment in wildlife disease surveillance is aimed at identifying the risk of spillover from wildlife to human populations where they interact. However, host species diversity is highest in the most intact habitats away from human habitation and most of the potential host species within these habitats are unsampled for infections. This is particularly true in biodiverse tropical ecosystems where the prevalence and identity of infections are the least known. We screened for presence of trypanosomes in 2,335 specimens from 66 species of rodents and shrews sampled from 11 mountain areas on the tropical island of Sulawesi, Indonesia. Our sampling spanned from the edge of human occupation into the most intact forests available on the island with sampling elevations ranging from 220 to 2,700 m. The two most common Trypanosoma species we detected were a native species from the Theileri clade (19.0 % of samples) and an introduced species from the Lewisi clade (5.1 % of murid rodent samples). Both species were detected at all elevations, extending from village edges to mountain peaks, but both reached their highest prevalence above 2,000 m elevation in the most intact forest away from human habitation. If these patterns with trypanosome infections are typical of other zoonotic diseases, wildlife disease surveillance would need to shift resources to study host-pathogen dynamics in more remote ecosystems. Sampling focused on the breadth of biodiversity, such as collected by and housed in natural history collections, is needed to further our understanding of zoonotic diseases and their prevalence.]]></p></abstract>
<abstract abstract-type="short" xml:lang="es"><p><![CDATA[Las enfermedades zoonóticas, incluidas las transmitidas por mamíferos hospedadores, plantean una amenaza importante para la salud humana en todo el mundo y se ha realizado una inversión sustancial en la vigilancia de enfermedades de la fauna silvestre para identificar el riesgo de contagio de la fauna silvestre a las poblaciones humanas con las que interactúan. Sin embargo, la diversidad de especies hospedadoras es mayor en los hábitats más intactos alejados de la habitación humana y la mayoría de las especies hospedadoras potenciales dentro de estos hábitats no han sido muestreadas para detectar infecciones. Esto es particularmente cierto en los ecosistemas tropicales biodiversos donde la prevalencia e identidad de las infecciones son las menos conocidas. Analizamos la presencia de tripanosomas en 2.335 especímenes de 66 especies de roedores y musarañas muestreadas en 11 áreas montañosas de la isla tropical de Sulawesi, Indonesia. Nuestro muestreo abarcó desde el límite de la ocupación humana hasta los bosques más intactos disponibles en la isla, con elevaciones de muestreo que oscilaron entre 220 y 2.700 m. Resultados: Las dos especies de Trypanosoma más comunes que detectamos fueron una especie nativa del clado Theileri (19.0 % de las muestras) y una especie introducida del clado Lewisi (5,1 % de las muestras de roedores múridos). Ambas especies se detectaron en todas las elevaciones, desde los límites de las aldeas hasta los picos de las montañas, pero ambas alcanzaron su prevalencia más alta por encima de los 2000 m de altitud en el bosque más intacto alejado de la habitación humana. Si estos patrones con infecciones por tripanosoma son típicos de otras enfermedades zoonóticas, la vigilancia de enfermedades de la vida silvestre necesitaría reorientar los recursos para estudiar la dinámica huésped-patógeno en ecosistemas más remotos. Se necesita un muestreo centrado en la amplitud de la biodiversidad, como la recolectada y almacenada en colecciones de historia natural, para mejorar nuestra comprensión de las enfermedades zoonóticas y su prevalencia.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Muridae]]></kwd>
<kwd lng="en"><![CDATA[kinetoplastid]]></kwd>
<kwd lng="en"><![CDATA[18S ribosomal DNA (rDNA)]]></kwd>
<kwd lng="en"><![CDATA[parasite]]></kwd>
<kwd lng="en"><![CDATA[prevalence]]></kwd>
<kwd lng="en"><![CDATA[rodent]]></kwd>
<kwd lng="en"><![CDATA[Trypanosoma]]></kwd>
<kwd lng="en"><![CDATA[shrews]]></kwd>
<kwd lng="en"><![CDATA[One Health]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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