<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1870-7203</journal-id>
<journal-title><![CDATA[Acta médica Grupo Ángeles]]></journal-title>
<abbrev-journal-title><![CDATA[Acta méd. Grupo Ángeles]]></abbrev-journal-title>
<issn>1870-7203</issn>
<publisher>
<publisher-name><![CDATA[Grupo Ángeles, Servicios de Salud]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1870-72032024000500366</article-id>
<article-id pub-id-type="doi">10.35366/118812</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Correlación clínica de la reacción en cadena de la polimerasa multipatógena en comparación con hemocultivo en pacientes con sepsis]]></article-title>
<article-title xml:lang="en"><![CDATA[Clinical correlation of multipathogenic polymerase chain reaction compared to blood culture in patients with sepsis]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Núñez Hernández]]></surname>
<given-names><![CDATA[Juan Carlos]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
<xref ref-type="aff" rid="A a"/>
<xref ref-type="aff" rid="A1"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Nieves Pérez]]></surname>
<given-names><![CDATA[César Adolfo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ceballos Vázquez Tagle]]></surname>
<given-names><![CDATA[Benito Gerardo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Figueroa Camacho]]></surname>
<given-names><![CDATA[Miguel Ángel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gerónimo Guevara]]></surname>
<given-names><![CDATA[Nancy]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Díaz Greene]]></surname>
<given-names><![CDATA[Enrique Juan]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez Weber]]></surname>
<given-names><![CDATA[Federico Leopoldo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Angeles Pedregal  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad La Salle México Facultad Mexicana de Medicina ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad Nacional Autónoma de México Facultad de Medicina ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Hospital Angeles Pedregal Laboratorio Clínico ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af5">
<institution><![CDATA[,Universidad La Salle Facultad Mexicana de Medicina ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2024</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2024</year>
</pub-date>
<volume>22</volume>
<numero>5</numero>
<fpage>366</fpage>
<lpage>370</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S1870-72032024000500366&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S1870-72032024000500366&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S1870-72032024000500366&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen:  Introducción:  la sepsis es una condición médica grave con alta mortalidad y desafíos diagnósticos, particularmente con las limitaciones de los hemocultivos, retrasando tratamientos vitales y aumentando riesgos de resistencias a antibióticos. El panel de sepsis, basado en reacción en cadena de la polimerasa (PCR), promete una identificación rápida y precisa de patógenos, siendo eficaz en infecciones fúngicas y en resistencia a antibióticos.  Objetivo:  comparar la eficacia de la PCR multipatógena frente a los hemocultivos en pacientes con sepsis en el &#8220;Hospital Angeles Pedregal&#8221;.  Material y métodos:  la investigación, realizada entre 2021 y 2022, se centró en pacientes con sepsis, proponiendo hipótesis sobre la correlación entre ambas técnicas diagnósticas. El diseño observacional e histórico no incluyó un grupo de control, optando por un muestreo no aleatorio y el análisis estadístico de datos clínicos detallados, bajo estrictas medidas de confidencialidad y supervisión ética.  Resultados:  se incluyeron 56 participantes, predominando hombres, con edad media de 62 años y diversas comorbilidades. La correlación entre PCR y hemocultivos fue significativa (p = 0.035), pese a que otros análisis estadísticos mostraron resultados mixtos.  Conclusión:  el estudio subraya el potencial de la PCR multipatógena en diagnóstico de sepsis, abogando por su integración con prácticas establecidas para mejorar la atención personalizada y los resultados en pacientes.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract:  Introduction:  sepsis is a severe medical condition with high mortality and diagnostic challenges, particularly with the limitations of blood cultures, delaying vital treatments, and increasing risks of antibiotic resistance. The PCR-based sepsis panel promises rapid and accurate identification of pathogens and is effective in fungal infections and antibiotic resistance.  Objective:  to compare the efficacy of multipathogen PCR versus blood cultures in patients with sepsis at &#8220;Hospital Angeles Pedregal&#8221;.  Material and methods:  the research, carried out between 2021 and 2022, focused on patients with sepsis, proposing hypotheses on the correlation between both diagnostic techniques. The observational and historical design did not include a control group, opting for non-random sampling and statistical analysis of detailed clinical data under strict confidentiality measures and ethical supervision.  Results:  56 participants were included, predominantly men, with a mean age of 62 and various comorbidities. The correlation between PCR and blood cultures was significant (p = 0.035), although other statistical analyses showed mixed results.  Conclusion:  the study highlights the potential of multipathogen PCR in sepsis diagnosis, advocating its integration with established practices to improve personalized care and patient outcomes.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[sepsis]]></kwd>
<kwd lng="es"><![CDATA[reacción en cadena de polimerasa]]></kwd>
<kwd lng="es"><![CDATA[hemocultivo]]></kwd>
<kwd lng="es"><![CDATA[diagnóstico molecular]]></kwd>
<kwd lng="es"><![CDATA[técnicas y procedimientos diagnósticos]]></kwd>
<kwd lng="en"><![CDATA[sepsis]]></kwd>
<kwd lng="en"><![CDATA[polymerase chain reaction]]></kwd>
<kwd lng="en"><![CDATA[blood culture]]></kwd>
<kwd lng="en"><![CDATA[molecular diagnostics]]></kwd>
<kwd lng="en"><![CDATA[diagnostic techniques and procedures]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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