<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1870-7203</journal-id>
<journal-title><![CDATA[Acta médica Grupo Ángeles]]></journal-title>
<abbrev-journal-title><![CDATA[Acta méd. Grupo Ángeles]]></abbrev-journal-title>
<issn>1870-7203</issn>
<publisher>
<publisher-name><![CDATA[Grupo Ángeles, Servicios de Salud]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1870-72032024000100065</article-id>
<article-id pub-id-type="doi">10.35366/114598</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Enfermedad por anticuerpos contra glicoproteínas de oligodendrocitos de mielina]]></article-title>
<article-title xml:lang="en"><![CDATA[Anti-myelin oligodendrocyte glycoprotein antibody disease]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sánchez García]]></surname>
<given-names><![CDATA[Angela Andrea]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Avila Perfino]]></surname>
<given-names><![CDATA[María Denise]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Bravo Valle]]></surname>
<given-names><![CDATA[Jaime]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gómez Pérez]]></surname>
<given-names><![CDATA[María de Guadalupe]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad La Salle Hospital Angeles Pedregal ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Angeles Pedregal  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital Angeles Pedregal  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2024</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2024</year>
</pub-date>
<volume>22</volume>
<numero>1</numero>
<fpage>65</fpage>
<lpage>68</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S1870-72032024000100065&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S1870-72032024000100065&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S1870-72032024000100065&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: La enfermedad asociada a anticuerpos contra glicoproteínas de oligodendrocitos de mielina (MOG) (MOGAD, por sus siglas en inglés) es un trastorno infrecuente y descrito recientemente. Cubre un amplio espectro de manifestaciones y se define por la presencia de seropositividad para MOG que se presenta principalmente en niños y adultos jóvenes; constituye una entidad dentro del espectro de enfermedades inflamatorias. En una proporción de pacientes puede haber una superposición en algunas de las manifestaciones clínicas y radiológicas entre MOGAD, esclerosis múltiple (EM) y otras enfermedades desmielinizantes. Afecta todo el sistema nervioso con predilección por el nervio óptico y médula espinal, con manifestaciones como neuritis óptica, la mielitis transversa y la encefalomielitis diseminada aguda, entre otros. La presencia de características clínicas y paraclínicas específicas de esta entidad es de gran ayuda en el diagnóstico temprano, confirmado con la detección de anticuerpos anti-MOG en un ensayo basado en células, permite instaurar un tratamiento adecuado lo antes posible con implicación pronóstica de la enfermedad. Presentamos un caso de un masculino joven con síntomas representativos de la misma, los hallazgos radiológicos más relevantes, una discusión y revisión de la literatura actual.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ Abstract: Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a rare, recently described disorder that covers a broad spectrum of manifestations and is defined by the presence of myelin oligodendrocyte glycoprotein (MOG) seropositivity that occurs mainly in children and young adults, which constitutes an entity within the spectrum of inflammatory diseases. In a proportion of patients, there may be an overlap in some of the clinical and radiological manifestations between MOGAD, multiple sclerosis (MS) and other demyelinating diseases. It affects the entire nervous system with a predilection for the optic nerve and spinal cord, with manifestations such as optic neuritis, transverse myelitis and acute disseminated encephalomyelitis, among others. The presence of specific clinical and paraclinical characteristics of this entity are of great help in early diagnosis, confirmed with the detection of anti-MOG antibodies in a cell-based assay, and allow to establish an adequate treatment as soon as possible with prognostic implication of the disease. We present a case of a young male with representative symptoms, the most relevant radiological findings, a discussion and review of the current literature.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[glicoproteínas de oligodendrocitos de mielina]]></kwd>
<kwd lng="es"><![CDATA[encefalomielitis diseminada aguda]]></kwd>
<kwd lng="es"><![CDATA[neuromielitis óptica]]></kwd>
<kwd lng="en"><![CDATA[myelin oligodendrocyte glycoprotein]]></kwd>
<kwd lng="en"><![CDATA[acute disseminated encephalomyelitis]]></kwd>
<kwd lng="en"><![CDATA[neuromyelitis optica]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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</back>
</article>
