<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1870-7203</journal-id>
<journal-title><![CDATA[Acta médica Grupo Ángeles]]></journal-title>
<abbrev-journal-title><![CDATA[Acta méd. Grupo Ángeles]]></abbrev-journal-title>
<issn>1870-7203</issn>
<publisher>
<publisher-name><![CDATA[Grupo Ángeles, Servicios de Salud]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1870-72032023000400381</article-id>
<article-id pub-id-type="doi">10.35366/112651</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Vasculitis primaria del sistema nervioso central]]></article-title>
<article-title xml:lang="en"><![CDATA[Primary vasculitis of the central nervous system]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Alcocer Maldonado]]></surname>
<given-names><![CDATA[José Luis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Domínguez Carrillo]]></surname>
<given-names><![CDATA[Luis Gerardo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Angeles León División de Cirugía. ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de Guanajuato Facultad de Medicina de León ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2023</year>
</pub-date>
<volume>21</volume>
<numero>4</numero>
<fpage>381</fpage>
<lpage>383</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S1870-72032023000400381&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S1870-72032023000400381&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S1870-72032023000400381&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen:  Introducción:  la vasculitis primaria del sistema nervioso central (VPSNC) no es frecuente, con presentación clínica heterogénea.  Caso clínico:  femenino de 35 años de edad con cefalea de siete días de evolución, sin mejoría con analgésicos, aunado a vómito y estupor, hemiparesia derecha y afasia en las últimas 24 horas; la tomografía axial computarizada (TAC) mostró hemorragias en núcleo caudado derecho y lóbulo frontal izquierdo; los exámenes de laboratorio incluyendo anticuerpos y reactantes de fase aguda fueron normales; la panangiografía mostró patrón de vasculitis de ramos troncales en arterias cerebrales y oclusión del seno longitudinal inferior, con diagnóstico de posible VPSNC se le practicó drenaje de hemorragia frontal y toma de biopsia, la cual confirmó el diagnóstico, así se inició tratamiento con bolos de metilprednisolona y ciclofosfamida, con lo que se obtuvo mejoría clínica.  Conclusiones:  la VPSNC presenta manifestaciones clínicas heterogéneas de déficit neurológico adquirido, por lo que es un reto y su diagnóstico implica existencia de: a) déficit neurológico adquirido inexplicable por otra causa; b) evidencias angiográficas o histopatológicas de VPSNC; y c) ausencia de vasculitis sistémica u otra condición que lo explique.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract:  Introduction:  primary vasculitis of the central nervous system (PVCNS) is rare, with heterogeneous clinical presentation.  Case report:  35-years-old female with seven days with headache, without improvement with analgesics, adding vomiting and stupor, right hemiparesis, and aphasia; CT showed hemorrhages in the right caudate nucleus and left frontal lobe, laboratory tests including antibodies and acute phase reactants normal; pan-angiography showed: a pattern of vasculitis of trunk branches in cerebral arteries and occlusion of the inferior longitudinal sinus; with a diagnosis of possible PVCNS. Drainage of frontal hemorrhage and biopsy was performed, which confirmed the diagnosis; beginning treatment with methylprednisolone bolus and cyclophosphamide, obtaining clinical improvement.  Conclusions:  PVCNS presents heterogeneous clinical manifestations of acquired neurological deficits; it is a challenge. Its diagnosis implies the existence of the following: a) the acquired neurological deficit, unexplained by another cause, b) angiographic or histopathological evidence of PVCNS, c) absence of systemic vasculitis or other condition that explains it.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[vasculitis primaria]]></kwd>
<kwd lng="es"><![CDATA[sistema nervioso central]]></kwd>
<kwd lng="es"><![CDATA[hemorragia cerebral]]></kwd>
<kwd lng="en"><![CDATA[primary vasculitis]]></kwd>
<kwd lng="en"><![CDATA[central nervous system]]></kwd>
<kwd lng="en"><![CDATA[cerebral hemorrhage]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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</article>
