<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1870-7203</journal-id>
<journal-title><![CDATA[Acta médica Grupo Ángeles]]></journal-title>
<abbrev-journal-title><![CDATA[Acta méd. Grupo Ángeles]]></abbrev-journal-title>
<issn>1870-7203</issn>
<publisher>
<publisher-name><![CDATA[Grupo Ángeles, Servicios de Salud]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1870-72032023000300241</article-id>
<article-id pub-id-type="doi">10.35366/111346</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Hallazgos tomográficos en casos sospechosos de COVID-19 y su asociación con escala CO-RADS en pacientes con prueba RT-PCR negativa]]></article-title>
<article-title xml:lang="en"><![CDATA[Tomographic findings in suspected cases of COVID-19 and their association with the CO-RADS scale in patients with a negative RT-PCR test]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez Ortiz]]></surname>
<given-names><![CDATA[Catherine Vianey]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[González Vergara]]></surname>
<given-names><![CDATA[Carolina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Figueroa García]]></surname>
<given-names><![CDATA[Juan]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad La Salle Departamento de Radiología e Imagen Facultad Mexicana de Medicina]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Angeles Mocel Departamento de Radiología e Imagen ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad La Salle Facultad Mexicana de Medicina ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2023</year>
</pub-date>
<volume>21</volume>
<numero>3</numero>
<fpage>241</fpage>
<lpage>246</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S1870-72032023000300241&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S1870-72032023000300241&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S1870-72032023000300241&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen:  Introducción:  a partir de la pandemia por COVID-19 en 2020, el diagnóstico temprano fue crucial para el tratamiento. La RT-PCR es el estándar para el diagnóstico de la infección y se puede ver limitada en cierto grupo de pacientes, por lo que la tomografía de tórax tiene un papel importante en la detección oportuna.  Objetivo:  determinar la prevalencia de los hallazgos tomográficos de tórax en pacientes que tienen sospecha clínica de COVID-19 y resultado RT-PCR negativo, así como su relación con la escala CO-RADS de acuerdo con la Sociedad Radiológica Holandesa.  Material y métodos:  se realizó un estudio transversal, observacional y retrospectivo en pacientes con sospecha clínica de COVID-19 y prueba RT-PCR negativa mediante hisopado nasofaríngeo, que posteriormente se sometieron a tomografía computarizada de tórax para su diagnóstico. La clasificación tomográfica se evaluó mediante la escala CO-RADS de acuerdo con la Sociedad Radiológica Holandesa.  Resultados:  se analizó un total de 113 pacientes, predominó el sexo masculino con 60% y la edad promedio fue de 58.4 años. Los principales hallazgos tomográficos encontrados fueron opacidades en vidrio despulido con 77%, seguido de patrón adoquinado y consolidación en menor proporción. En cuanto a la relación con la escala CO-RADS, las pruebas tuvieron significancia estadística con un valor de p &lt; 0.05, al encontrar que la mayoría de los pacientes se determinaron en una clasificación de alta sospecha de la enfermedad, CO-RADS 5.  Conclusión:  los hallazgos tomográficos principales en pacientes con sospecha clínica de enfermedad COVID-19 y prueba RT-PCR negativa son similares a los reportados en la literatura, lo cual se asocia con los hallazgos basados en la escala CO-RADS donde se observa una alta sospecha de la enfermedad, pese a la prueba confirmatoria RT-PCR negativa.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract:  Introduction:  since COVID-19 pandemic in 2020, early diagnosis was crucial for the treatment. RT-PCR is the standard for the diagnosis of infection and may be limited in a certain group of patients, so chest tomography plays an important role in early detection.  Objective:  determine the prevalence of chest tomographic findings in patients with clinical suspicion of COVID-19 and negative RT-PCR result and their association with the CO-RADS scale.  Material and methods:  a cross-sectional, observational, retrospective study was carried out in patients with clinical suspicion of COVID-19 and negative RT-PCR test by nasopharyngeal swab, subsequently undergoing diagnostic chest computed tomography. According to the Dutch Radiological Society, the tomographic classification was evaluated using the CO-RADS scale.  Results:  a total of 113 patients were analyzed, predominantly male, with 60%, and the average age was 58.4 years. The main tomographic findings were ground glass opacities with 77%, followed by a &#8220;crazy paving&#8221; pattern and consolidation to a lesser extent. Regarding the relationship with the CO-RADS scale, the tests had statistical significance with a p &lt; 0.05, finding that most of the patients were classified as having high suspicion of the disease, CO-RADS 5.  Conclusion:  the main tomographic findings in patients with clinical suspicion of COVID-19 illness and a negative RT-PCR test are like reported in the literature, which is associated with the fundamentals in the CO-RADS scale, where a high suspicion of the disease is observed, despite a negative confirmatory RT-PCR test.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[coronavirus]]></kwd>
<kwd lng="es"><![CDATA[RT-PCR negativa]]></kwd>
<kwd lng="es"><![CDATA[tomografía tórax]]></kwd>
<kwd lng="es"><![CDATA[CO-RADS]]></kwd>
<kwd lng="es"><![CDATA[vidrio despulido]]></kwd>
<kwd lng="en"><![CDATA[coronavirus]]></kwd>
<kwd lng="en"><![CDATA[RT-PCR negative]]></kwd>
<kwd lng="en"><![CDATA[chest tomography]]></kwd>
<kwd lng="en"><![CDATA[CO-RADS]]></kwd>
<kwd lng="en"><![CDATA[ground glass opacities]]></kwd>
</kwd-group>
</article-meta>
</front><back>
<ref-list>
<ref id="B1">
<label>1</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Carotti]]></surname>
<given-names><![CDATA[M]]></given-names>
</name>
<name>
<surname><![CDATA[Salaffi]]></surname>
<given-names><![CDATA[F]]></given-names>
</name>
<name>
<surname><![CDATA[Sarzi-Puttini]]></surname>
<given-names><![CDATA[P]]></given-names>
</name>
<name>
<surname><![CDATA[Agostini]]></surname>
<given-names><![CDATA[A]]></given-names>
</name>
<name>
<surname><![CDATA[Borgheresi]]></surname>
<given-names><![CDATA[A]]></given-names>
</name>
<name>
<surname><![CDATA[Minorati]]></surname>
<given-names><![CDATA[D]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Chest CT features of coronavirus disease 2019 (COVID-19) pneumonia: key points for radiologists]]></article-title>
<source><![CDATA[Radiol Med]]></source>
<year>2020</year>
<volume>125</volume>
<numero>7</numero>
<issue>7</issue>
<page-range>636-46</page-range></nlm-citation>
</ref>
<ref id="B2">
<label>2</label><nlm-citation citation-type="book">
<source><![CDATA[25o Informe epidemiológico de la situación de COVID-19. Dirección de Información Epidemiológica, 21 de junio de 2021 [Internet]]]></source>
<year>2021</year>
<publisher-loc><![CDATA[México ]]></publisher-loc>
<publisher-name><![CDATA[Secretaría de Salud]]></publisher-name>
</nlm-citation>
</ref>
<ref id="B3">
<label>3</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Xiao]]></surname>
<given-names><![CDATA[AT]]></given-names>
</name>
<name>
<surname><![CDATA[Tong]]></surname>
<given-names><![CDATA[YX]]></given-names>
</name>
<name>
<surname><![CDATA[Zhang]]></surname>
<given-names><![CDATA[S]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[False negative of RT-PCR and prolonged nucleic acid conversion in COVID-19: Rather than recurrence]]></article-title>
<source><![CDATA[J Med Virol]]></source>
<year>2020</year>
<volume>92</volume>
<numero>10</numero>
<issue>10</issue>
<page-range>1755-6</page-range></nlm-citation>
</ref>
<ref id="B4">
<label>4</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Ai]]></surname>
<given-names><![CDATA[T]]></given-names>
</name>
<name>
<surname><![CDATA[Yang]]></surname>
<given-names><![CDATA[Z]]></given-names>
</name>
<name>
<surname><![CDATA[Hou]]></surname>
<given-names><![CDATA[H]]></given-names>
</name>
<name>
<surname><![CDATA[Zhan]]></surname>
<given-names><![CDATA[C]]></given-names>
</name>
<name>
<surname><![CDATA[Chen]]></surname>
<given-names><![CDATA[C]]></given-names>
</name>
<name>
<surname><![CDATA[Lv]]></surname>
<given-names><![CDATA[W]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Correlation of chest CT and RT-PCR testing for coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases]]></article-title>
<source><![CDATA[Radiology]]></source>
<year>2020</year>
<volume>296</volume>
<numero>2</numero>
<issue>2</issue>
<page-range>E32-40</page-range></nlm-citation>
</ref>
<ref id="B5">
<label>5</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Juárez-Hernández]]></surname>
<given-names><![CDATA[F]]></given-names>
</name>
<name>
<surname><![CDATA[García-Benítez]]></surname>
<given-names><![CDATA[MP]]></given-names>
</name>
<name>
<surname><![CDATA[Hurtado-Duarte]]></surname>
<given-names><![CDATA[AM]]></given-names>
</name>
<name>
<surname><![CDATA[Rojas-Varela]]></surname>
<given-names><![CDATA[R]]></given-names>
</name>
<name>
<surname><![CDATA[Farías-Contreras]]></surname>
<given-names><![CDATA[JP]]></given-names>
</name>
<name>
<surname><![CDATA[Pensado]]></surname>
<given-names><![CDATA[PLE]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Hallazgos tomográficos en afectación pulmonar por COVID-19, experiencia inicial en el Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Ciudad de México]]></article-title>
<source><![CDATA[Neumol Cir Tórax]]></source>
<year>2020</year>
<volume>79</volume>
<numero>2</numero>
<issue>2</issue>
<page-range>71-7</page-range></nlm-citation>
</ref>
<ref id="B6">
<label>6</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[González]]></surname>
<given-names><![CDATA[VC]]></given-names>
</name>
<name>
<surname><![CDATA[Arias]]></surname>
<given-names><![CDATA[MRE]]></given-names>
</name>
<name>
<surname><![CDATA[Villalón]]></surname>
<given-names><![CDATA[DRJ]]></given-names>
</name>
<name>
<surname><![CDATA[Delgado]]></surname>
<given-names><![CDATA[NM]]></given-names>
</name>
<name>
<surname><![CDATA[Saucedo]]></surname>
<given-names><![CDATA[MEM]]></given-names>
</name>
<name>
<surname><![CDATA[Rodríguez]]></surname>
<given-names><![CDATA[OCV]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Correlación de carga viral con prueba RT-PCR en infección por SARS-CoV-2 y hallazgos en tomografía computarizada de tórax]]></article-title>
<source><![CDATA[Acta Med GA]]></source>
<year>2020</year>
<volume>18</volume>
<numero>4</numero>
<issue>4</issue>
<page-range>382-9</page-range></nlm-citation>
</ref>
<ref id="B7">
<label>7</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Prokop]]></surname>
<given-names><![CDATA[M]]></given-names>
</name>
<name>
<surname><![CDATA[van Everdingen]]></surname>
<given-names><![CDATA[W]]></given-names>
</name>
<name>
<surname><![CDATA[van Rees Vellinga]]></surname>
<given-names><![CDATA[T]]></given-names>
</name>
<name>
<surname><![CDATA[Quarles van Ufford]]></surname>
<given-names><![CDATA[H]]></given-names>
</name>
<name>
<surname><![CDATA[Stoger]]></surname>
<given-names><![CDATA[L]]></given-names>
</name>
<name>
<surname><![CDATA[Beenen]]></surname>
<given-names><![CDATA[L]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[CO-RADS: a categorical CT assessment scheme for patients suspected of having COVID-19-definition and evaluation]]></article-title>
<source><![CDATA[Radiology]]></source>
<year>2020</year>
<volume>296</volume>
<numero>2</numero>
<issue>2</issue>
<page-range>E97-E104</page-range></nlm-citation>
</ref>
<ref id="B8">
<label>8</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Koo]]></surname>
<given-names><![CDATA[HJ]]></given-names>
</name>
<name>
<surname><![CDATA[Choi]]></surname>
<given-names><![CDATA[SH]]></given-names>
</name>
<name>
<surname><![CDATA[Sung]]></surname>
<given-names><![CDATA[H]]></given-names>
</name>
<name>
<surname><![CDATA[Choe]]></surname>
<given-names><![CDATA[J]]></given-names>
</name>
<name>
<surname><![CDATA[Do]]></surname>
<given-names><![CDATA[KH]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[RadioGraphics update: radiographic and CT features of viral pneumonia]]></article-title>
<source><![CDATA[Radiographics]]></source>
<year>2020</year>
<volume>40</volume>
<numero>4</numero>
<issue>4</issue>
<page-range>E8-E15</page-range></nlm-citation>
</ref>
<ref id="B9">
<label>9</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Xie]]></surname>
<given-names><![CDATA[S]]></given-names>
</name>
<name>
<surname><![CDATA[Lei]]></surname>
<given-names><![CDATA[Z]]></given-names>
</name>
<name>
<surname><![CDATA[Chen]]></surname>
<given-names><![CDATA[X]]></given-names>
</name>
<name>
<surname><![CDATA[Liu]]></surname>
<given-names><![CDATA[W]]></given-names>
</name>
<name>
<surname><![CDATA[Wang]]></surname>
<given-names><![CDATA[X]]></given-names>
</name>
<name>
<surname><![CDATA[Dong]]></surname>
<given-names><![CDATA[Y]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Chest CT-based differential diagnosis of 28 patients with suspected corona virus disease 2019 (COVID-19)]]></article-title>
<source><![CDATA[Br J Radiol]]></source>
<year>2020</year>
<volume>93</volume>
<numero>1112</numero>
<issue>1112</issue>
<page-range>20200243</page-range></nlm-citation>
</ref>
<ref id="B10">
<label>10</label><nlm-citation citation-type="book">
<source><![CDATA[Informe técnico diario COVID-19 México]]></source>
<year>2020</year>
<publisher-loc><![CDATA[México ]]></publisher-loc>
<publisher-name><![CDATA[Secretaría de Salud]]></publisher-name>
</nlm-citation>
</ref>
<ref id="B11">
<label>11</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Pontone]]></surname>
<given-names><![CDATA[G]]></given-names>
</name>
<name>
<surname><![CDATA[Scafuri]]></surname>
<given-names><![CDATA[S]]></given-names>
</name>
<name>
<surname><![CDATA[Mancini]]></surname>
<given-names><![CDATA[ME]]></given-names>
</name>
<name>
<surname><![CDATA[Agalbato]]></surname>
<given-names><![CDATA[C]]></given-names>
</name>
<name>
<surname><![CDATA[Guglielmo]]></surname>
<given-names><![CDATA[M]]></given-names>
</name>
<name>
<surname><![CDATA[Baggiano]]></surname>
<given-names><![CDATA[A]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Role of computed tomography in COVID-19]]></article-title>
<source><![CDATA[J Cardiovasc Comput Tomogr]]></source>
<year>2021</year>
<volume>15</volume>
<numero>1</numero>
<issue>1</issue>
<page-range>27-36</page-range></nlm-citation>
</ref>
<ref id="B12">
<label>12</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Long]]></surname>
<given-names><![CDATA[C]]></given-names>
</name>
<name>
<surname><![CDATA[Xu]]></surname>
<given-names><![CDATA[H]]></given-names>
</name>
<name>
<surname><![CDATA[Shen]]></surname>
<given-names><![CDATA[Q]]></given-names>
</name>
<name>
<surname><![CDATA[Zhang]]></surname>
<given-names><![CDATA[X]]></given-names>
</name>
<name>
<surname><![CDATA[Fan]]></surname>
<given-names><![CDATA[B]]></given-names>
</name>
<name>
<surname><![CDATA[Wang]]></surname>
<given-names><![CDATA[C]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Diagnosis of the coronavirus disease (COVID-19): rRT-PCR or CT?]]></article-title>
<source><![CDATA[Eur J Radiol]]></source>
<year>2020</year>
<volume>126</volume>
<page-range>108961</page-range></nlm-citation>
</ref>
<ref id="B13">
<label>13</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Vila Muntadas]]></surname>
<given-names><![CDATA[M]]></given-names>
</name>
<name>
<surname><![CDATA[Agustí Sunyer]]></surname>
<given-names><![CDATA[I]]></given-names>
</name>
<name>
<surname><![CDATA[Agustí Garcia-Navarro]]></surname>
<given-names><![CDATA[A]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[COVID-19 diagnostic tests: importance of the clinical context]]></article-title>
<source><![CDATA[Med Clin (Barc)]]></source>
<year>2021</year>
<volume>157</volume>
<numero>4</numero>
<issue>4</issue>
<page-range>185-90</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
