<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1870-7203</journal-id>
<journal-title><![CDATA[Acta médica Grupo Ángeles]]></journal-title>
<abbrev-journal-title><![CDATA[Acta méd. Grupo Ángeles]]></abbrev-journal-title>
<issn>1870-7203</issn>
<publisher>
<publisher-name><![CDATA[Grupo Ángeles, Servicios de Salud]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1870-72032018000400357</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Síndrome de McKittrick-Wheelock]]></article-title>
<article-title xml:lang="en"><![CDATA[McKittrick-Wheelock syndrome]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Boyer Duck]]></surname>
<given-names><![CDATA[Estefanía]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Alfeiran Ruiz]]></surname>
<given-names><![CDATA[Antonio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Montes De Oca Orellana]]></surname>
<given-names><![CDATA[Claudio René]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Flores Palomar]]></surname>
<given-names><![CDATA[Francisco José]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ortiz Monasterio]]></surname>
<given-names><![CDATA[Todd Iván]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Estradas Trujillo]]></surname>
<given-names><![CDATA[José Alberto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez Gómez]]></surname>
<given-names><![CDATA[Adriana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Muñoz Aizpuru]]></surname>
<given-names><![CDATA[Edna]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Ángeles Pedregal  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Ángeles Pedregal  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital &#8220;Dr. Manuel GEA González&#8221;  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Hospital Ángeles Pedregal  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af5">
<institution><![CDATA[,Hospital Ángeles Pedregal  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af6">
<institution><![CDATA[,Hospital Central Sur de Alta Especialidad Pemex Picacho  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2018</year>
</pub-date>
<volume>16</volume>
<numero>4</numero>
<fpage>357</fpage>
<lpage>360</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S1870-72032018000400357&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S1870-72032018000400357&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S1870-72032018000400357&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen:  Introducción:  El síndrome de Mckittrick-Wheelock es un cuadro caracterizado por depleción hidroelectrolítica, secundario a diarrea hipersecretora debido a un adenoma velloso de recto de gran tamaño. Se postula su causa por hipersecreción de prostaglandina E2. El adenoma se presenta con mayor frecuencia en recto.  Caso clínico:  Masculino de 60 años con cuadro diarreico de un año de evolución multitratada, es sometido a hemicolectomía izquierda, por hallazgo de adenoma aserrado de recto.  Conclusiones:  La manifestación clínica es con diarrea y deshidratación, se ha probado tratamiento con indometacina para disminuir la secreción de prostaglandina E2, siendo el tratamiento definitivo el quirúrgico.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract:  Introduction:  The Mckittrick-Wheelock syndrome is characterized by hydroelectrolytic depletion, secondary to hypersecretory diarrhea due to a large villous adenoma of the rectum. Its cause is postulated by hypersecretion of prostaglandin E2. The adenoma occurs most frequently in the rectum.  Case report:  A 60-year-old male with chronic diarrheal, one year of evolution, with multiple tratments, underwent a left hemicolectomy due to the finding of a serrated adenoma of the rectum.  Conclusions:  The condition is characterized by diarrhea and severe dehydration; treatment with indomenthacin has been tried to decrease the secretion of prostaglandin E2, being the definitive treatment, surgery.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Síndrome de McKittrick-Wheelock]]></kwd>
<kwd lng="es"><![CDATA[adenoma serrado]]></kwd>
<kwd lng="es"><![CDATA[diarrea hipersecretora]]></kwd>
<kwd lng="es"><![CDATA[adenoma velloso]]></kwd>
<kwd lng="en"><![CDATA[McKittrick-Wheelock syndrome]]></kwd>
<kwd lng="en"><![CDATA[serrated adenoma]]></kwd>
<kwd lng="en"><![CDATA[hypersecretory diarrhea]]></kwd>
<kwd lng="en"><![CDATA[villous adenoma]]></kwd>
</kwd-group>
</article-meta>
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