Safety of UV radiation for autofluorescence diagnosis of skin cancer
J.A. Delgadoa, I. Quesadaa, L.M. Montañob y L. Anasagastic
a Department of Physics, Centre for Technological Applications and Nuclear Development, CEADEN-CITMA, P.O. Box 6122. Havana, Cuba. Currently at INAOE, Tonantzintla, Puebla, México.
b Department of Physics, CINVESTAV-IPN, Apartado Postal 14-740, 07000 México, D.F. México.
c National Institute of Oncology and Radiobiology, INOR-MINSAP, P.O. Box 6024, Havana, Cuba.
]]>Recibido el 10 de agosto de 2005;
Aceptado el 8 de diciembre de 2005.
Abstract
It has been demonstrated that ex-vivo human skin autofluorescence is different for healthy and diseased tissue. In order to use these results for in vivo clinical applications, it is necessary to guarantee safe levels of UV radiation during skin scanning of patients and protect the eyes from scattered UV radiation coming from the skin surface. One of the goals of this work is to extend maximum limits of exposure to ultraviolet radiation in the spectral region between 315 and 400 nm. We also analyze irradiation levels of typical commercial ultraviolet LEDs and semiconductor lasers for application on skin cancer demarcation. Experimental measurements were not carried out in this paper.
Keywords: Ultraviolet; skin cancer; exposure; laser.
Resumen
Se ha demostrado que la autofluorescencia en la piel humana ex-vivo es diferente para tejidos sanos y enfermos. Para usar estos resultados en aplicaciones clínicas in vivo, es necesario garantizar niveles seguros de radiación UV durante la exploración de la piel de pacientes y proteger los ojos de la dispersión de la radiación UV que proviene de la superficie de la piel. Uno de los objetivos de este trabajo es proveer de una guía de los límites máximos de exposición a la radiación ultravioleta en la región espectral entre 315 y 400 nm. También han sido analizados los niveles de irradiación de los LEDs ultravioleta comerciales típicos y de láseres semiconductores para la aplicación en la demarcación del cáncer de piel. No se realizaron mediciones experimentales en este trabajo.
]]> Descriptores: Ultravioleta; cáncer de piel; exposición; laser.
PACS: 87.50.Gi; 28.80.Fj
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