<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1665-5044</journal-id>
<journal-title><![CDATA[Revista mexicana de neurociencia]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. mex. neurocienc.]]></abbrev-journal-title>
<issn>1665-5044</issn>
<publisher>
<publisher-name><![CDATA[Academia Mexicana de Neurología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1665-50442022000300080</article-id>
<article-id pub-id-type="doi">10.24875/rmn.19000078</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Frequency of hypertension, age and gender in cerebrovascular disease in Paraguay]]></article-title>
<article-title xml:lang="es"><![CDATA[Frecuencia de la hipertensión arterial, la edad y el género en la enfermedad cerebrovascular en Paraguay]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Díaz-Escobar]]></surname>
<given-names><![CDATA[Luis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Flores]]></surname>
<given-names><![CDATA[Alan]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Seró-Ballesteros]]></surname>
<given-names><![CDATA[Laia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Otto]]></surname>
<given-names><![CDATA[Christian]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mernes]]></surname>
<given-names><![CDATA[Ricardo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Pedrozo]]></surname>
<given-names><![CDATA[Fátima]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Riquelme]]></surname>
<given-names><![CDATA[Fabiola]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gonzalez]]></surname>
<given-names><![CDATA[Romina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Nacional de Asunción Facultad de Ciencias Médicas ]]></institution>
<addr-line><![CDATA[San Lorenzo ]]></addr-line>
<country>Paraguay</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2022</year>
</pub-date>
<volume>23</volume>
<numero>3</numero>
<fpage>80</fpage>
<lpage>85</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S1665-50442022000300080&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S1665-50442022000300080&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S1665-50442022000300080&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Background: Hypertension, age, and gender are relevant factors associated to cerebrovascular disease. In Paraguay, cerebrovascular disease is the fourth cause of mortality; however, information about demographics and baseline characteristics is not widely knowledge. Our aim was determinate the prevalence of hypertension, age, and gender in the setting of acute-phase stroke in our population.  Methods: This is a descriptive, single-center study. Data were collected from a prospective registry of stroke patients admitted in the stroke unit of our center, from April 2015 to December 2016.  Results: From 996 stroke patients, 252 (25.3%) presented intracerebral hemorrhage (ICH). Three hundred ninety (39.1%) were female. The hypertension rate was 74% and 78% in ischemic stroke and ICH, respectively, being hypertensive hemorrhagic etiology 79.5% of the ICH and lacunar infarct 11.6% of ischemic strokes. In ICH patients, mean age differences between genders were remarkable (mean years 55.41 [SD ± 14.8] vs. 62.48 [SD ± 15.2] p &#8804; 0.001). In the multivariant analysis, lower age than 60 years old (OR: 4.893; CI 95%: 1.772-13.509 p = 0.029) and higher systolic blood pressure at admission (OR: 1.098; CI 95% 1.044-1.155, p = 0.009) were independent factors associated to ICH.  Conclusion: In our population, ICH rates are similar to regional findings, occurring at an early age than other series, being remarkable in males. Hypertension rates in ischemic stroke and ICH are higher than other series, and the variability of presumed hypertensive microangiopathy phenotype could be in relation to age (hypertensive hemorrhage vs. lacunar). These findings would be related to ethnics, social, environment, and geographies factors.]]></p></abstract>
<abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Background: La hipertensión, la edad y el género son factores relevantes asociados a enfermedad cerebrovascular (ECV). En Paraguay, la ECV es la cuarta causa de mortalidad, sin embargo, la información sobre sus características no es de amplio conocimiento. Nuestro objetivo fue determinar la frecuencia de la hipertensión, la edad y el género en la ECV en fase aguda en nuestra población.  Métodos: Se trata de un estudio observacional descriptivo monocéntrico. Se recogieron datos de un registro prospectivo de pacientes con ictus ingresados en la Unidad de Ictus de nuestro centro, desde abril de 2015 a marzo de 2019.  Resultados: De 996 pacientes con ictus, 252 (25,3%) presentaron hemorragia intracerebral (HIC). Trescientos noventa (39.1%) fueron mujeres. La tasa de hipertensión arterial fue elevada tanto en isquémicos (74%) como en hemorrágicos (78%), siendo la hemorragia hipertensiva el 79.5% de las HIC y los lacunares, el 11.6% de ictus isquémicos. En pacientes con HIC, la diferencia de edad entre géneros fue significativa (media/años 55.41 (SD ± 14.8) vs. 62.48 (SD ± 15.2) p &#8804; 0.001). En el análisis multivariante, fueron factores independientes asociados a HIC: la edad menor a 60 años (OR: 4.893; IC 95%: 1.772-13.509 p = 0.029) y una elevada presión arterial sistólica al ingreso (OR: 1.098; IC 95% 1.044-1.155, p = 0.009).  Conclusión: En nuestra población, la frecuencia de HIC es similar a lo descrito en la región, observándose una edad más temprana que en otras series y siendo remarcable en el género masculino. La tasa de hipertensión en HIC e ictus isquémico es mayor que en otras series y la variación de distintos fenotipos por presunta microangiopatía hipertensiva estaría relacionado en parte a la edad (hemorragia hipertensiva vs. lacunares). Estos resultados podrían explicarse por razones étnicas, socioambientales y geográficas.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Stroke epidemiology]]></kwd>
<kwd lng="en"><![CDATA[Hypertensive hemorrhage]]></kwd>
<kwd lng="en"><![CDATA[Female stroke]]></kwd>
<kwd lng="en"><![CDATA[Vascular risk factors]]></kwd>
<kwd lng="en"><![CDATA[Intracerebral hemorrhage]]></kwd>
<kwd lng="es"><![CDATA[Ictus epidemiologia]]></kwd>
<kwd lng="es"><![CDATA[Hemorragia cerebral hipertensiva]]></kwd>
<kwd lng="es"><![CDATA[Ictus en la mujer]]></kwd>
<kwd lng="es"><![CDATA[Factores de riesgo]]></kwd>
<kwd lng="es"><![CDATA[Hemorragia intracerebral]]></kwd>
</kwd-group>
</article-meta>
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