<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1665-5044</journal-id>
<journal-title><![CDATA[Revista mexicana de neurociencia]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. mex. neurocienc.]]></abbrev-journal-title>
<issn>1665-5044</issn>
<publisher>
<publisher-name><![CDATA[Academia Mexicana de Neurología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1665-50442019000200062</article-id>
<article-id pub-id-type="doi">10.24875/rmn.m22000088</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Guía clínica. Evaluación prequirúrgica en epilepsia refractaria]]></article-title>
<article-title xml:lang="en"><![CDATA[Clinical guideline. Pre-operative evaluation of epilepsy surgery]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ruiz-García]]></surname>
<given-names><![CDATA[Matilde]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Alonso-Vanegas]]></surname>
<given-names><![CDATA[Mario A.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Pérez-Reyes]]></surname>
<given-names><![CDATA[Sara P.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Quiñones-Canales]]></surname>
<given-names><![CDATA[Gerardo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez-Leyva]]></surname>
<given-names><![CDATA[Ildefonso]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Martínez-Rodríguez]]></surname>
<given-names><![CDATA[Héctor R.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Barragán-Pérez]]></surname>
<given-names><![CDATA[Eduardo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Nacional de Pediatría  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital HGM  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital Regional de Alta Especialidad del Bajío  ]]></institution>
<addr-line><![CDATA[León Guanajuato]]></addr-line>
<country>México</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Instituto de Seguridad y Servicios Sociales para los Trabajadores del Estado Hospital General ]]></institution>
<addr-line><![CDATA[Durango ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af5">
<institution><![CDATA[,Universidad Autónoma de San Luis Potosí Facultad de Medicina ]]></institution>
<addr-line><![CDATA[San Luis Potosí ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af6">
<institution><![CDATA[,Instituto Tecnológico y de Estudios Superiores de Monterrey  ]]></institution>
<addr-line><![CDATA[Monterrey Nuevo León]]></addr-line>
<country>México</country>
</aff>
<aff id="Af7">
<institution><![CDATA[,Hospital Infantil de México Federico Gómez  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>04</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>04</month>
<year>2019</year>
</pub-date>
<volume>20</volume>
<numero>2</numero>
<fpage>62</fpage>
<lpage>68</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S1665-50442019000200062&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S1665-50442019000200062&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S1665-50442019000200062&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen La cirugía de epilepsia es un tratamiento aprobado para el manejo de la epilepsia refractaria a tratamiento farmacológico (ERF). Aproximadamente un tercio de pacientes con epilepsia cursan con ERF, un grave problema de salud pública con consecuencias biopsicosociales importantes que incluyen accidentes, limitaciones profesionales y riesgo de muerte súbita incrementado. La cirugía permite alcanzar libertad de crisis en aproximadamente el 65% de los pacientes operados en seguimiento a 5 años. Los pacientes con epilepsia refractaria deben ser referidos a un centro especializado para evaluación prequirúrgica. La evaluación prequirúgica (como mínimo) incluye: el análisis clínico detallado, electroencefalografía, vídeo-electroencefalografía, resonancia magnética (RM) cerebral, evaluación neuropsicológica y/o del desarrollo y evaluación psiquiátrica. Los procedimientos quirúrgicos más frecuentes son las resecciones del lóbulo temporal, seguidas por resecciones extratemporales y/o multilobares, lesionectomía, hemisferectomía, callosotomías y transecciones piales.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Epilepsy surgery is an approved treatment for the management of drug-resistant epilepsy. Approximately one third of patients with epilepsy present refractory epilepsy (RE). RE is considered a grave public health threat, carrying important bio-psycho-social consequences including accidents, professional limitations and increased risk of sudden death. Surgery is associated with seizure freedom in approximately 65% of patients after five years of follow-up. Patients with drug-resistant epilepsy should be referred to a specialized center for presurgical evaluation. Presurgical evaluation requires minimally detailed clinical analysis, electroencephalogram, video-electroencephalogram, magnetic resonance imaging, neuropsychological and developmental evaluation, and psychiatric evaluation. The most frequent surgical procedures are temporal lobe resections, followed by extratemporal and multilobar resections, lesionectomy, hemispherectomies, callosotomies and multiple subpial transections.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Cirugía]]></kwd>
<kwd lng="es"><![CDATA[Epilepsia]]></kwd>
<kwd lng="es"><![CDATA[Evaluación prequirúrgica]]></kwd>
<kwd lng="en"><![CDATA[Surgery]]></kwd>
<kwd lng="en"><![CDATA[Epilepsy]]></kwd>
<kwd lng="en"><![CDATA[Pre-surgical evaluation]]></kwd>
</kwd-group>
</article-meta>
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<given-names><![CDATA[P]]></given-names>
</name>
<name>
<surname><![CDATA[Kahane]]></surname>
<given-names><![CDATA[P]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Does epilepsy surgery lower the mortality of drug-resistant epilepsy?]]></article-title>
<source><![CDATA[Epilepsy Res]]></source>
<year>2003</year>
<volume>56</volume>
<page-range>105-20</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
