<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1665-5044</journal-id>
<journal-title><![CDATA[Revista mexicana de neurociencia]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. mex. neurocienc.]]></abbrev-journal-title>
<issn>1665-5044</issn>
<publisher>
<publisher-name><![CDATA[Academia Mexicana de Neurología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1665-50442019000200056</article-id>
<article-id pub-id-type="doi">10.24875/rmn.m19000049</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Guía clínica. Estado epiléptico en niños y adultos]]></article-title>
<article-title xml:lang="en"><![CDATA[Clinical guide. Status epilepticus in children and adults]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Olmos-López]]></surname>
<given-names><![CDATA[Alejandro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ibarra-Aguilar]]></surname>
<given-names><![CDATA[Jorge]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Cornelio-Nieto]]></surname>
<given-names><![CDATA[José O.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ocaña-Hernández]]></surname>
<given-names><![CDATA[Luis A.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Márquez-Amaya]]></surname>
<given-names><![CDATA[Mario A.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Luna-López]]></surname>
<given-names><![CDATA[Norberto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Reséndiz-Aparicio]]></surname>
<given-names><![CDATA[Juan C.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez-Leyva]]></surname>
<given-names><![CDATA[Ildefonso]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital General de Cuernavaca Dr. José G. Parres  ]]></institution>
<addr-line><![CDATA[Morelos ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital del Niño del DIF  ]]></institution>
<addr-line><![CDATA[Pachuca Hidalgo]]></addr-line>
<country>México</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital de Alta Especialidad del Niño Dr. Rodolfo Nieto Padrón  ]]></institution>
<addr-line><![CDATA[Villahermosa Tabasco]]></addr-line>
<country>México</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Instituto Mexicano del Seguro Social Unidad Médica de Alta Especialidad H.E. N.º 71 ]]></institution>
<addr-line><![CDATA[Torreón ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af5">
<institution><![CDATA[,Hospital Regional  ]]></institution>
<addr-line><![CDATA[Delicias Chihuahua]]></addr-line>
<country>México</country>
</aff>
<aff id="Af6">
<institution><![CDATA[,Facultad de Medicina de Minatitlan  ]]></institution>
<addr-line><![CDATA[Veracruz ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af7">
<institution><![CDATA[,Instituto Nacional de Neurología y Neurocirugía Dr. Manuel Velasco Suárez  ]]></institution>
<addr-line><![CDATA[Ciudad de México Edo. de México]]></addr-line>
<country>México</country>
</aff>
<aff id="Af8">
<institution><![CDATA[,Hospital Central Dr. Ignacio Morones Prieto  ]]></institution>
<addr-line><![CDATA[San Luis Potosí Edo. de México]]></addr-line>
<country>México</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>04</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>04</month>
<year>2019</year>
</pub-date>
<volume>20</volume>
<numero>2</numero>
<fpage>56</fpage>
<lpage>61</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S1665-50442019000200056&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S1665-50442019000200056&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S1665-50442019000200056&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen Una crisis epiléptica generalizada que dura cinco o más minutos, o la presencia de dos o más crisis sin recuperación de la consciencia en un periodo de 30 minutos, o una crisis focal que persiste durante más de 10 minutos o con alteración de la consciencia durante 60 minutos o más de duración, se denomina estado epiléptico. Puede dividirse en generalizado y focal, en motor y no motor. Su etiología puede o no reconocerse. El patrón electroencefalográfico muestra actividad epiléptica persistente focal o generalizada. Es una situación grave, que requiere un manejo algorítmico desde que se detecta en Urgencias y, si lo requiere, en la Unidad de Terapia Intensiva (UTI). El manejo intrahospitalario incluye el ABCDE inicial, solución glucosada hipertónica y tiamina si se detectó hipoglucemia; lorazepam (midazolam o diazepam) para yugular las crisis, seguido de fenitoína, valproato o levetiracetam en impregnación y sostén. Si el estado epiléptico persiste durante más de una hora pasará a una UTI con intubación y administración continua de midazolam, propofol o tiopental con intubación y monitorización continua. Si no cede con dos fármacos se denomina estado epiléptico refractario y si continúa durante 24 horas o más se reconoce como superrefractario. Hasta un tercio de los pacientes muere.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract A generalized epileptic seizure lasting five or more minutes, or the presence of two or more seizures without recovery of consciousness in thirty minutes, or a focal seizure that persists for more than 10 min or with altered consciousness for 60 min or more duration is called status epilepticus. It can be classified into generalized and focal, motor and non-motor. Its etiology may or may not be recognized. The electroencephalographic pattern shows focal or generalized persistent epileptic activity. It is a dangerous situation, which requires algorithmic management since it is detected, in the emergency Room and if required in the intensive therapy unit. In-hospital management would include the initial ABCDE , hypertonic glucose solution and thiamin if hypoglycemia is detected. Lorazepam (midazolam or diazepam) to juggle seizures, followed by phenytoin, valproate or levetiracetam in impregnation and sustain. If the status epilepticus persists for more than an hour, the patient will be referred to an ICU with intubation and continuous administration of midazolam, propofol or thiopental with intubation and continuous monitoring. If it does not yield with two drugs, it is called refractory epileptic status, and if it continues for 24 h or more, it is recognized as super-refractory. A third of these patients die.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Estado epiléptico]]></kwd>
<kwd lng="es"><![CDATA[Crisis epilépticas]]></kwd>
<kwd lng="es"><![CDATA[Focal]]></kwd>
<kwd lng="es"><![CDATA[Generalizado]]></kwd>
<kwd lng="es"><![CDATA[Motor]]></kwd>
<kwd lng="es"><![CDATA[Tratamiento agudo]]></kwd>
<kwd lng="en"><![CDATA[Status epilepticus]]></kwd>
<kwd lng="en"><![CDATA[Seizures]]></kwd>
<kwd lng="en"><![CDATA[Focal]]></kwd>
<kwd lng="en"><![CDATA[Generalized]]></kwd>
<kwd lng="en"><![CDATA[Motor]]></kwd>
<kwd lng="en"><![CDATA[Acute treatment]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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