1665-1456 1665-1456 S1665-14562020000300125 10.18633/biotecnia.v22i3.1197 Mexico Mexico Mexico 00 00 2020 00 00 2020 22 3 125 130

2004 215 100-10 1990 11 50-6 2009 20 1697-708 2012 80 5 5 1163-1169-1112 2019 6 2 2 105-22 2004 14 648-56 2010 5 1008 2013 62 241-7 2012 60 3820 2016 16 77-90 2005 123 5 5 861-73 1998 28 449-61 2001 9 472-4 2002 61 212-7 1993 139 585-90 1975 31 1614 2011 63 470-6 2007 31 819-25 2014 36 530-3 2014 3 801-12 2011 63 470-6 2007 139 74-80 World Health Organization 2019