<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1405-5546</journal-id>
<journal-title><![CDATA[Computación y Sistemas]]></journal-title>
<abbrev-journal-title><![CDATA[Comp. y Sist.]]></abbrev-journal-title>
<issn>1405-5546</issn>
<publisher>
<publisher-name><![CDATA[Instituto Politécnico Nacional, Centro de Investigación en Computación]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1405-55462025000201015</article-id>
<article-id pub-id-type="doi">10.13053/cys-29-2-5699</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[DNA Characterization Through Nanotechnology-Assisted Bioimpedance and Feature Extraction for Artificial Intelligence]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Alcantar-Jacobo]]></surname>
<given-names><![CDATA[Mara Y.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ruiz Romero]]></surname>
<given-names><![CDATA[Jorge A.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[López-Madrigal]]></surname>
<given-names><![CDATA[Jaime E.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Arias-González]]></surname>
<given-names><![CDATA[Leticia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sánchez-Monroy]]></surname>
<given-names><![CDATA[Virginia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[González-Díaz]]></surname>
<given-names><![CDATA[César A.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Tecnológico Superior de Ciudad Hidalgo  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Instituto Politécnico Nacional Escuela Superior de Medicina ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2025</year>
</pub-date>
<volume>29</volume>
<numero>2</numero>
<fpage>1015</fpage>
<lpage>1020</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S1405-55462025000201015&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S1405-55462025000201015&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S1405-55462025000201015&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: Detecting Deoxyribonucleic Acids (DNA) through their electrical properties is a technique that has not been fully explored. Developing biosensors for detecting label-free DNA without functionalizing transducer surfaces continues to be a relevant technological challenge. Our research group has reported multi-frequency bioimpedance measurements as a potential technique for estimating concentrations of total DNA free of labeling and functionalization. Post-processing techniques, feature extraction, and Artificial Intelligence (AI) algorithms are required for automatic classification and bioimpedance parameters identification that might be used to detect DNA and its concentration. This article explores multi-frequency bioimpedance measurements assisted with magnetic nanoparticles and post-processing AI feature extraction to correlate characteristical bioimpedance parameters with DNA concentrations and purity. Post-processing estimation of the area under the Cole plot seems a relevant feature to correlate with DNA concentration and purity. The results indicate relevant evidence proposing DNA characterization through nanotechnology-assisted bioimpedance and AI.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Bioimpedance]]></kwd>
<kwd lng="en"><![CDATA[DNA]]></kwd>
<kwd lng="en"><![CDATA[magnetic nanoparticles]]></kwd>
</kwd-group>
</article-meta>
</front><back>
<ref-list>
<ref id="B1">
<nlm-citation citation-type="book">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Buscaglia]]></surname>
<given-names><![CDATA[L.A.]]></given-names>
</name>
</person-group>
<source><![CDATA[Development of a Portable Impedance Spectrometer]]></source>
<year>2022</year>
<publisher-name><![CDATA[Instituto de Física de São Carlos, Universidade de São Paulo]]></publisher-name>
</nlm-citation>
</ref>
<ref id="B2">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Navarro]]></surname>
<given-names><![CDATA[K.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Nanomateriales: Optimización en la extracción de ADN]]></article-title>
<source><![CDATA[México Ciencia y Tecnología]]></source>
<year>2018</year>
</nlm-citation>
</ref>
<ref id="B3">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Chengzhou]]></surname>
<given-names><![CDATA[Z.]]></given-names>
</name>
<name>
<surname><![CDATA[Guohai]]></surname>
<given-names><![CDATA[Y.]]></given-names>
</name>
<name>
<surname><![CDATA[Él]]></surname>
<given-names><![CDATA[L.]]></given-names>
</name>
<name>
<surname><![CDATA[Dan]]></surname>
<given-names><![CDATA[D.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Electrochemical Sensors and Biosensors Based on Nanomaterials and Nanostructures]]></article-title>
<source><![CDATA[ACS Publications]]></source>
<year>2014</year>
<volume>71</volume>
<numero>1</numero>
<issue>1</issue>
</nlm-citation>
</ref>
<ref id="B4">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Sui]]></surname>
<given-names><![CDATA[J.]]></given-names>
</name>
<name>
<surname><![CDATA[Gandotra]]></surname>
<given-names><![CDATA[N.]]></given-names>
</name>
<name>
<surname><![CDATA[Xie]]></surname>
<given-names><![CDATA[P.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Multi-frequency impedance sensing for detection and sizing of DNA fragments]]></article-title>
<source><![CDATA[Sci Rep]]></source>
<year>2021</year>
<volume>11</volume>
<numero>6490</numero>
<issue>6490</issue>
</nlm-citation>
</ref>
<ref id="B5">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Buscaglia]]></surname>
<given-names><![CDATA[L.A.]]></given-names>
</name>
<name>
<surname><![CDATA[Oliveira]]></surname>
<given-names><![CDATA[O.N.]]></given-names>
</name>
<name>
<surname><![CDATA[Carmo]]></surname>
<given-names><![CDATA[J.P.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Roadmap for Electrical Impedance Spectroscopy for Sensing: A Tutorial]]></article-title>
<source><![CDATA[IEEE Sensors Journal]]></source>
<year>2021</year>
<page-range>22246-57</page-range></nlm-citation>
</ref>
<ref id="B6">
<nlm-citation citation-type="book">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Bhatt]]></surname>
<given-names><![CDATA[G.]]></given-names>
</name>
<name>
<surname><![CDATA[Bhatt]]></surname>
<given-names><![CDATA[M.]]></given-names>
</name>
<name>
<surname><![CDATA[Bhattacharya]]></surname>
<given-names><![CDATA[S.]]></given-names>
</name>
</person-group>
<source><![CDATA[Impedance Spectroscopy and its Application in Biological Detection]]></source>
<year>2023</year>
<publisher-name><![CDATA[CRC Press]]></publisher-name>
</nlm-citation>
</ref>
<ref id="B7">
<nlm-citation citation-type="">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Chemicell Media]]></surname>
<given-names><![CDATA[K.]]></given-names>
</name>
</person-group>
<source><![CDATA[Ferrofluids: Ferromagnetic Particles in Carrier Fluid: Fluidmag]]></source>
<year>2007</year>
</nlm-citation>
</ref>
</ref-list>
</back>
</article>
