<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1405-5546</journal-id>
<journal-title><![CDATA[Computación y Sistemas]]></journal-title>
<abbrev-journal-title><![CDATA[Comp. y Sist.]]></abbrev-journal-title>
<issn>1405-5546</issn>
<publisher>
<publisher-name><![CDATA[Instituto Politécnico Nacional, Centro de Investigación en Computación]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1405-55462004000200004</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[On Modelling an Immune System]]></article-title>
<article-title xml:lang="es"><![CDATA[Sobre un Modelo Computacional del Sistema Inmune]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Monroy]]></surname>
<given-names><![CDATA[Raúl]]></given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Saab]]></surname>
<given-names><![CDATA[Rosa]]></given-names>
</name>
<xref ref-type="aff" rid="A02"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Godínez]]></surname>
<given-names><![CDATA[Fernando]]></given-names>
</name>
<xref ref-type="aff" rid="A03"/>
</contrib>
</contrib-group>
<aff id="A01">
<institution><![CDATA[,Tecnológico de Monterrey Departamento de Ciencias Computacionales ]]></institution>
<addr-line><![CDATA[México ]]></addr-line>
<country>México</country>
</aff>
<aff id="A02">
<institution><![CDATA[,Instituto Tecnológico y de Estudios Superiores  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<aff id="A03">
<institution><![CDATA[,Tecnológico de Monterrey Centro de Sistemas Inteligentes ]]></institution>
<addr-line><![CDATA[Monterrey Nuevo León]]></addr-line>
<country>México</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2004</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2004</year>
</pub-date>
<volume>7</volume>
<numero>4</numero>
<fpage>249</fpage>
<lpage>259</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S1405-55462004000200004&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S1405-55462004000200004&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S1405-55462004000200004&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Immune systems of live forms have been an abundant source of inspiration to contemporary computer scientists. Problem solving strategies, stemming from known immune system phenomena, have been successfully applied to challenging problems of modern computing. However, research in artificial immune systems has overlooked establishing a coherent model of known immune system behaviour. This paper aims reports on an preliminary computer model of an immune system, where each immune system component is specified in terms of its observable behaviour using a suitable process algebra. Our model is not only suitable to simulation but also and more importantly to formal analyzes of immune system behaviour.]]></p></abstract>
<abstract abstract-type="short" xml:lang="es"><p><![CDATA[El sistema inmune de los seres vivientes ha sido una fuente rica de inspiración para científicos en computación contemporáneos. Estrategias de solución de problemas, cuyos orígenes se encuentran en fenómenos inmunológicos, han sido exitosamente aplicadas en problemas desafiantes de la computación moderna. Sin embargo, el trabajo de investigación en sistemas inmunológicos artificiales ha ignorado el establecer un modelo coherente que incorpore comportamientos conocidos y aceptados del sistema inmune. Este artículo reporta un modelo computacional preliminar del sistema inmune, en el cual cada componente del mismo es especificado en términos de su comportamiento observable, usando una álgebra de procesos adecuada. Nuestro modelo no sólo es adecuado para la simulación sino también y aún más importante para el análisis formal del comportamiento de un sistema inmune.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Multiagent systems and Distributed AI]]></kwd>
<kwd lng="en"><![CDATA[Immunology]]></kwd>
<kwd lng="en"><![CDATA[Immune Based Computer Systems]]></kwd>
<kwd lng="es"><![CDATA[Sistemas Multiagentes y AI Distribuida]]></kwd>
<kwd lng="es"><![CDATA[Inmunología]]></kwd>
<kwd lng="es"><![CDATA[Sistemas de Cómputo basado en Inmunidad]]></kwd>
</kwd-group>
</article-meta>
</front><body><![CDATA[ <p align="justify"><font face="verdana" size="4">Art&iacute;culo</font></p>     <p align="center"><font face="verdana" size="2">&nbsp;</font></p>     <p align="center"><font face="verdana" size="4"><b>On Modelling an Immune System</b></font></p>     <p align="center"><font face="verdana" size="2">&nbsp;</font></p>     <p align="center"><font face="verdana" size="3"><b><i>Sobre un Modelo Computacional del Sistema Inmune</i></b></font></p>     <p align="center"><font face="verdana" size="2">&nbsp;</font></p>     <p align="center"><font face="verdana" size="2"><b>Ra&uacute;l Monroy<sup>1</sup>, Rosa Saab<sup>2</sup> and Fernando God&iacute;nez<sup>3</sup></b></font></p>     <p align="justify"><font face="verdana" size="2">&nbsp;</font></p>     <p align="justify"><font face="verdana" size="2"><i><sup>1</sup> Departamento de Ciencias Computacionales, Campus Estado de M&eacute;xico del Tecnol&oacute;gico de Monterrey Carretera al lago de Guadalupe Km 3.5, Col. Margarita Maza de Ju&aacute;rez, Atizap&aacute;n de Zaragoza, 52926, M&eacute;xico, M&eacute;xico. E&#150;mail: <a href="mailto:raulm@items.mx">raulm@items.mx</a></i></font></p>     <p align="justify"><font face="verdana" size="2"><i><sup>2 </sup>Instituto Tecnol&oacute;gico y de Estudios Superiores de Coacalco, 16 de Septiembre 54, Col. Cabecera Municipal, Coacalco de Berrioz&aacute;bal,  Estado de M&eacute;xico, 55717, M&eacute;xico. E&#150;mail: <a href="mailto:rosa.saab@itesm.mx">rosa.saab@itesm.mx</a></i></font></p>     ]]></body>
<body><![CDATA[<p align="justify"><font face="verdana" size="2"><i><sup>3</sup> Centro de Sistemas Inteligentes, Campus Monterrey del Tecnol&oacute;gico de Monterrey, CETEC Torre Sur 5o Piso, Eugenio Garza Sada  2501, Monterrey, Nuevo Le&oacute;n, 64849, M&eacute;xico. E&#150;mail: <a href="mailto:fgodinez@itesm.mx">fgodinez@itesm.mx</a></i></font></p>     <p align="justify"><font face="verdana" size="2">&nbsp;</font></p>     <p align="justify"><font face="verdana" size="2">Article received on March 27, 2003    <br> Accepted on June 08, 2004</font></p>     <p align="justify"><font face="verdana" size="2">&nbsp;</font></p>     <p align="justify"><font face="verdana" size="2"><b>Abstract</b></font></p>     <p align="justify"><font face="verdana" size="2">Immune systems of live forms have been an abundant source of inspiration to contemporary computer scientists. Problem solving strategies, stemming from known immune system phenomena, have been successfully applied to challenging problems of modern computing. However, research in artificial immune systems has overlooked establishing a coherent model of known immune system behaviour. This paper aims reports on an preliminary computer model of an immune system, where each immune system component is specified in terms of its observable behaviour using a suitable process algebra. Our model is not only suitable to simulation but also and more importantly to formal analyzes of immune system behaviour. </font></p>     <p align="justify"><font face="verdana" size="2"><b>Keywords: </b>Multiagent systems and Distributed AI, Immunology, Immune Based Computer Systems.</font></p>     <p align="justify"><font face="verdana" size="2">&nbsp;</font></p>     <p align="justify"><font face="verdana" size="2"><b>Resumen</b></font></p>     ]]></body>
<body><![CDATA[<p align="justify"><font face="verdana" size="2">El sistema inmune de los seres vivientes ha sido una fuente rica de inspiraci&oacute;n para cient&iacute;ficos en computaci&oacute;n contempor&aacute;neos. Estrategias de soluci&oacute;n de problemas, cuyos or&iacute;genes se encuentran en fen&oacute;menos inmunol&oacute;gicos, han sido exitosamente aplicadas en problemas desafiantes de la computaci&oacute;n moderna. Sin embargo, el trabajo de investigaci&oacute;n en sistemas inmunol&oacute;gicos artificiales ha ignorado el establecer un modelo coherente que incorpore comportamientos conocidos y aceptados del sistema inmune. Este art&iacute;culo reporta un modelo computacional preliminar del sistema inmune, en el cual cada componente del mismo es especificado en t&eacute;rminos de su comportamiento observable, usando una &aacute;lgebra de procesos adecuada. Nuestro modelo no s&oacute;lo es adecuado para la simulaci&oacute;n sino tambi&eacute;n y a&uacute;n m&aacute;s importante para el an&aacute;lisis formal del comportamiento de un sistema inmune.</font></p>     <p align="justify"><font face="verdana" size="2"><b>Palabras Clave: </b>Sistemas Multiagentes y AI Distribuida, Inmunolog&iacute;a, Sistemas de C&oacute;mputo basado en Inmunidad.</font></p>     <p align="justify"><font face="verdana" size="2">&nbsp;</font></p>     <p align="justify"><font face="verdana" size="2"><a href="/pdf/cys/v7n4/v7n4a4.pdf" target="_blank">DESCARGAR ART&Iacute;CULO EN FORMATO PDF</a></font></p>     <p align="justify"><font face="verdana" size="2">&nbsp;</font></p>     <p align="justify"><font face="verdana" size="2"><b>Acknowledgements</b></font></p>     <p align="justify"><font face="verdana" size="2">This research was partially supported by CONACYT grants CONACYT&#150;BMBF J200.1442/2002 and 33337&#150;A.</font></p>     <p align="justify"><font face="verdana" size="2">&nbsp;</font></p>     <p align="justify"><font face="verdana" size="2"><b>References</b></font></p>     <!-- ref --><p align="justify"><font face="verdana" size="2">1. <b>R. 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<ref id="B27">
<label>27</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Tofts]]></surname>
<given-names><![CDATA[C]]></given-names>
</name>
</person-group>
<article-title xml:lang="en"><![CDATA[Processes with probabilities, priority and time]]></article-title>
<source><![CDATA[Formal Aspect s of Computing]]></source>
<year>1994</year>
<volume>6</volume>
<numero>5</numero>
<issue>5</issue>
<page-range>536-564</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
