<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0484-7903</journal-id>
<journal-title><![CDATA[Revista mexicana de anestesiología]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. mex. anestesiol.]]></abbrev-journal-title>
<issn>0484-7903</issn>
<publisher>
<publisher-name><![CDATA[Colegio Mexicano de Anestesiología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0484-79032025000200090</article-id>
<article-id pub-id-type="doi">10.35366/119201</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Recurrencia a 5 años de tumor maligno de ovario en cirugía citorreductora y anestesia multimodal vs anestesia general balanceada]]></article-title>
<article-title xml:lang="en"><![CDATA[5-year-old recurrence of a malignant ovarian tumor in cytoreductive surgery and multimodal anesthesia vs balanced general anesthesia]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Terán-Silva]]></surname>
<given-names><![CDATA[Tracy Patricia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Jiménez-Ríos]]></surname>
<given-names><![CDATA[Patricia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Olvera-Sumano]]></surname>
<given-names><![CDATA[Verónica]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Regional de Alta Especialidad de Oaxaca  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Regional de Alta Especialidad de Oaxaca  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad Regional del Sureste Hospital Regional de Alta Especialidad de Oaxaca Facultad de Medicina y Cirugía]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2025</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2025</year>
</pub-date>
<volume>48</volume>
<numero>2</numero>
<fpage>90</fpage>
<lpage>93</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0484-79032025000200090&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0484-79032025000200090&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0484-79032025000200090&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen:  Introducción:  la cirugía es una de las opciones de tratamiento de primera línea para numerosos tipos de cáncer; en las que el uso de opioides para el manejo del dolor trans y postoperatorio resulta necesario. Sin embargo, numerosos estudios asocian un efecto negativo de estos sobre la inmunorregulación y la recurrencia del cáncer.  Material y métodos:  estudio de cohorte, longitudinal, observacional, analítico, en pacientes con tumor maligno de ovario y cirugía citorreductora entre 2016 a 2018, en quienes fue evaluada la recurrencia tumoral a cinco años en dos grupos: aquellas pacientes sometidas a anestesia multimodal y un segundo grupo de pacientes sometidas a anestesia general balanceada.  Resultados:  se incluyeron 202 expedientes, observándose recurrencia tumoral en 80 pacientes (39.6%), de las cuales 14 (11.2%) fueron manejadas con anestesia general balanceada (AGB) y 66 (52.8%) con anestesia multimodal (AM). El grupo de AGB reportó un OR de 3.48 (IC95% 1.33-9.06); mientras que en el grupo de AM el OR fue de 0.29 (IC95% 0.11-0.74) veces mayor riesgo de recurrencia a cinco años.  Conclusiones:  la inclusión de la anestesia multimodal bloquea o disminuye la respuesta al estrés quirúrgico, así como de la respuesta inflamatoria, lo cual disminuye el uso intraoperatorio de anestésicos volátiles y minimiza el requerimiento de opioides; esto conduce a una mejor respuesta inmune y se traduce en menor riesgo de recurrencia a cinco años.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract:  Introduction:  surgery is one of the first-line treatment options for numerous types of cancer; in which the use of opioids for the management of trans and post-operative pain is necessary; However, numerous studies associate a negative effect of these on immunoregulation and cancer recurrence.  Material and methods:  cohort study, longitudinal, observational, analytical, in patients with malignant ovarian tumor and cytoreductive surgery between 2016 to 2018, in whom tumor recurrence was evaluated at five years in two groups: those patients undergoing multimodal anesthesia and a second group of patients undergoing balanced general anesthesia.  Results:  202 files were included, with tumor recurrence observed in 80 (39.6%), of which: 14 (11.2%) were managed with balanced general anesthesia (AGB) and 66 (52.8%) with multimodal anesthesia (MA). The AGB group reported OR = 3.48 (95% CI 1.33-9.06); while in the MA group the OR = 0.29 (95% CI 0.11-0.74) times greater risk of recurrence at five years.  Conclusions:  the inclusion of multimodal anesthesia blocks or decreases the response to surgical stress, as well as the inflammatory response, reducing the intraoperative use of volatile anesthetics and minimizing the requirement for opioids; which leads to a better immune response and translates into a lower risk of recurrence at five years.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[anestesia multimodal]]></kwd>
<kwd lng="es"><![CDATA[recurrencia]]></kwd>
<kwd lng="es"><![CDATA[cáncer de ovario]]></kwd>
<kwd lng="en"><![CDATA[multimodal anesthesia]]></kwd>
<kwd lng="en"><![CDATA[recurrence]]></kwd>
<kwd lng="en"><![CDATA[ovarian cancer]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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