0484-7903 0484-7903 S0484-79032021000100051 10.35366/97777 Cuba Cuba Cuba 00 03 2021 00 03 2021 44 1 51 54

1 2013 17 347-56 2 2010 17 286-98 3 2009 37 356-72 4 2013 17 347-56 5 2014 25 602-9 6 Declaration of Montreal 7 2010 150 384-5 8 2011 24 1031-40 9 2016 157 8 8 1599-606 10 2016 6 121-50 11 2017 13 387-404 12 2012 12 403-13 13 2002 48 100-10 14 2014 18 94-100 15 2012 1 71-7 16 2010 18 17 2013 115 579-89 18 2009 16 445-67 19 2009 194 3-30 20 2009 27 1153-9 21 2010 56 139-42 22 2011 38 89-95 23 2011 30 15-20 24 2017 40 136-54 25 American Diabetes Association 2017 40 588-98 26 2011 27 629-38 27 28 2017 29 2017 6 CD007938 30 2014 7 CD010958 31 2018 35 3 3 160-7 32 FDA 33