<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0300-9041</journal-id>
<journal-title><![CDATA[Ginecología y obstetricia de México]]></journal-title>
<abbrev-journal-title><![CDATA[Ginecol. obstet. Méx.]]></abbrev-journal-title>
<issn>0300-9041</issn>
<publisher>
<publisher-name><![CDATA[Federación Mexicana de Colegios de Obstetricia y Ginecología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0300-90412022000700006</article-id>
<article-id pub-id-type="doi">10.24245/gom.v90i7.7662</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Hemorragias durante el primer trimestre del embarazo: revisión narrativa]]></article-title>
<article-title xml:lang="en"><![CDATA[Bleeding in the first trimester of pregnancy, narrative review]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Torres-Pineda]]></surname>
<given-names><![CDATA[Mariana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Urrego-Pachón]]></surname>
<given-names><![CDATA[Mauricio Arturo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Antioquia Facultad de Medicina ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de Antioquia Departamento de Ginecología y Obstetricia ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Colombia</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2022</year>
</pub-date>
<volume>90</volume>
<numero>7</numero>
<fpage>590</fpage>
<lpage>598</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0300-90412022000700006&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0300-90412022000700006&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0300-90412022000700006&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  ANTECEDENTES:  Las hemorragias durante el primer trimestre del embarazo son un problema que se atiende en la práctica clínica obstétrica diaria. Las conductas de atención suelen estar protocolizadas en casi todas las instituciones; sin embargo, la evidencia científica actual sugiere que algunas de esas conductas no tienen una evidencia sólida que las apoye.  OBJETIVO:  Revisar la bibliografía reciente y resumir las principales recomendaciones para la atención de casos de hemorragia en el primer trimestre del embarazo.  METODOLOGÍA:  Estudio retrospectivo basado en la búsqueda bibliográfica de artículos en inglés que contuvieran los términos MeSH: &#8220;First Trimester&#8221;, &#8220;Hemorrhage&#8221;, &#8220;Bleeding&#8221;, &#8220;Ectopic Pregnancy&#8221; &#8220;Abortion&#8221;, &#8220;Incomplete Abortion&#8221;, &#8220;Miscarriage&#8221;, &#8220;Early Pregnancy Loss&#8221;, &#8220;Threatened Abortion&#8221; y &#8220;Gestational Trophoblastic Disease&#8221;. Se incluyeron ensayos clínicos controlados, estudios de casos y controles, estudios de cohorte prospectivos y retrospectivos, guías de práctica clínica, protocolos, revisiones sistemáticas y metanálisis incluidos en la base de datos PubMed de 2014 a 2021.  RESULTADOS:  Se encontraron 54 artículos completos, de los que se descartaron 38 por duplicidad en la información, falta de pertinencia o no actualizados. Al final, solo se incluyeron 16 artículos para la revisión narrativa.  CONCLUSIONES:  Las hemorragias durante el primer trimestre, si bien son frecuentes no dejan de ser un reto diagnóstico por su amplio espectro de manifestaciones clínicas y causas. Siempre es necesario correlacionar la evaluación clínica completa con los hallazgos ecográficos y las concentraciones de &#946;-hCG y descartar las causas no obstétricas del sangrado, independientemente de la sospecha diagnóstica inicial.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  BACKGROUND:  Hemorrhage in the first trimester of pregnancy is a problem seen in daily obstetric clinical practice. Care behaviors are usually protocolized in almost all institutions; however, current scientific evidence suggests that some of these behaviors do not have strong evidence to support them.  OBJECTIVE:  To review the recent literature and summarize the main recommendations for the care of cases of hemorrhage in the first trimester of pregnancy.  METHODOLOGY:  Retrospective study based on a literature search of English language articles containing the MeSH terms: &#8220;First Trimester&#8221;, &#8220;Hemorrhage&#8221;, &#8220;Bleeding&#8221;, &#8220;Ectopic Pregnancy&#8221;, &#8220;Abortion&#8221;, &#8220;Incomplete Abortion&#8221;, &#8220;Miscarriage&#8221;, &#8220;Early Pregnancy Loss&#8221;, &#8220;Threatened Abortion&#8221; and &#8220;Gestational Trophoblastic Disease&#8221;. Controlled clinical trials, case-control studies, prospective and retrospective cohort studies, clinical practice guidelines, protocols, systematic reviews and meta-analyses included in the PubMed database from 2014 to 2021 were included.  RESULTS:  We found 54 complete articles, of which 38 were discarded due to duplicity in information, lack of relevance or not updated. In the end, only 16 articles were included for narrative review.  CONCLUSIONS:  First trimester hemorrhage, although frequent, is still a diagnostic challenge due to its wide spectrum of clinical manifestations and causes. It is always necessary to correlate the complete clinical evaluation with ultrasound findings and &#946;-hCG concentrations and to rule out nonobstetric causes of bleeding, regardless of the initial diagnostic suspicion.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Hemorragia]]></kwd>
<kwd lng="es"><![CDATA[primer trimestre]]></kwd>
<kwd lng="es"><![CDATA[embarazo]]></kwd>
<kwd lng="es"><![CDATA[Obstetricia]]></kwd>
<kwd lng="es"><![CDATA[estudio retrospectivo]]></kwd>
<kwd lng="es"><![CDATA[aborto espontáneo]]></kwd>
<kwd lng="en"><![CDATA[Hemorrhage]]></kwd>
<kwd lng="en"><![CDATA[First trimester]]></kwd>
<kwd lng="en"><![CDATA[Pregnancy]]></kwd>
<kwd lng="en"><![CDATA[Obstetric]]></kwd>
<kwd lng="en"><![CDATA[Retrospective Studies]]></kwd>
<kwd lng="en"><![CDATA[Abortion]]></kwd>
<kwd lng="en"><![CDATA[Spontaneous]]></kwd>
</kwd-group>
</article-meta>
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