<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0300-9041</journal-id>
<journal-title><![CDATA[Ginecología y obstetricia de México]]></journal-title>
<abbrev-journal-title><![CDATA[Ginecol. obstet. Méx.]]></abbrev-journal-title>
<issn>0300-9041</issn>
<publisher>
<publisher-name><![CDATA[Federación Mexicana de Colegios de Obstetricia y Ginecología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0300-90412020000600394</article-id>
<article-id pub-id-type="doi">10.24245/gom.v88i6.3579</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Mielinolisis extrapontina en una paciente embarazada, con hiperémesis e hiponatremia. Reporte de un caso]]></article-title>
<article-title xml:lang="en"><![CDATA[Extrapontine myelinolysis in a pregnant with hyperemesis and hyponatremia. A case report]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez-Pinto]]></surname>
<given-names><![CDATA[Fredlis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[García-Pardo]]></surname>
<given-names><![CDATA[Andrea]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ardila-Sierra]]></surname>
<given-names><![CDATA[Adriana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Castro]]></surname>
<given-names><![CDATA[Carlos Alberto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Fundación Universitaria de Ciencias de la Salud  ]]></institution>
<addr-line><![CDATA[Bogotá ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Fundación Universitaria de Ciencias de la Salud  ]]></institution>
<addr-line><![CDATA[Bogotá ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Fundación Universitaria de Ciencias de la Salud  ]]></institution>
<addr-line><![CDATA[Bogotá ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Fundación Universitaria de Ciencias de la Salud  ]]></institution>
<addr-line><![CDATA[Bogotá ]]></addr-line>
<country>Colombia</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2020</year>
</pub-date>
<volume>88</volume>
<numero>6</numero>
<fpage>394</fpage>
<lpage>401</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0300-90412020000600394&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0300-90412020000600394&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0300-90412020000600394&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen:  ANTECEDENTES: La mielinolisis extrapontina forma parte del síndrome de desmielinización osmótica que lesiona los oligodendrocitos y ocasiona la pérdida de mielina en regiones del sistema nervioso central diferentes al puente del tronco encefálico. Se origina por la corrección rápida de sodio en pacientes con hiponatremia y en mujeres embarazadas se asocia con hiperémesis gravídica.  CASO CLÍNICO: Paciente indígena, de 32 años, enviada a un hospital universitario de alta complejidad en Bogotá, desde un territorio de la Amazonia colombiana, en el marco de un nuevo modelo de salud, con embarazo de 15 semanas, quien tuvo un episodio convulsivo, afasia y automatismo bucal, con antecedente de hiperémesis gravídica y otro episodio de hiperémesis con hiponatremia un mes antes. Inicialmente se sospechó eclampsia y neuroinfección; se implementó tratamiento para la corrección rápida del sodio y prescripción de anticonvulsivos. La resonancia magnética cerebral fue compatible con mielinolisis extrapontina. Luego de un mes regresó a su territorio de origen para rehabilitación. Tuvo parto domiciliario a las 38.3 semanas y acudió al hospital para el alumbramiento.  CONCLUSIONES: La mielinolisis extrapontina debe considerarse en el diagnóstico diferencial entre embarazo con cuadro neurológico agudo y antecedente de hiperémesis e hiponatremia. Es importante integrar, sistemáticamente, hospitales universitarios o de alta complejidad en los territorios rurales para optimizar el diagnóstico y tratamiento de estas pacientes.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract:  BACKGROUND: Extrapontine myelinolysis is part of the osmotic demyelination syndrome, being an acute non-inflammatory demyelinating disease caused by hyperosmotic stress that injures oligodendrocytes and causes myelin loss in regions of the central nervous system other than the pons of the brain stem. Primarily caused by a rapid sodium correction in patients with hyponatremia, in pregnant women its most frequent association is with hyperemesis gravidarum.  CLINICAL CASE: A 32-year-old indigenous woman was referred to a university hospital of high complexity, in Bogotá, from a territory of the Colombian Amazon, within the framework of a new health care model, with a 15-week pregnancy, who had a convulsive episode, aphasia and oral automatism, and a recent history of hyperemesis gravidarum. Another history of hyperemesis and hyponatremia a month ago. Initially, eclampsia and neuroinfection were suspected, a rapid correction of sodium, anticonvulsant, remission and management in the intensive care unit was performed. MRI was compatible with extrapontin myelinolysis. After a month she returned to the territory of origin for rehabilitation. She had a home delivery at 38.3 weeks and went to the hospital for placental delivery.  CONCLUSION:  Extrapontin myelinolysis should be considered in the differential diagnosis between pregnancy with acute neurological symptoms conditions and a history of hyperemesis or hyponatremia. In case of a repeated history of acute hyponatremia in pregnant women with hyperemesis, chronicity should be considered. It is recommended to integrate university hospitals to rural territories to optimize the diagnosis and management of this type of cases.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Mielinolisis extrapontina]]></kwd>
<kwd lng="es"><![CDATA[tronco encefálico]]></kwd>
<kwd lng="es"><![CDATA[sodio]]></kwd>
<kwd lng="es"><![CDATA[embarazadas]]></kwd>
<kwd lng="es"><![CDATA[anciana indígena]]></kwd>
<kwd lng="es"><![CDATA[colombianas]]></kwd>
<kwd lng="es"><![CDATA[afasia]]></kwd>
<kwd lng="es"><![CDATA[hiperémesis gravídica]]></kwd>
<kwd lng="es"><![CDATA[hiponatremia]]></kwd>
<kwd lng="es"><![CDATA[eclampsia]]></kwd>
<kwd lng="en"><![CDATA[Extrapontine Myelinolysis]]></kwd>
<kwd lng="en"><![CDATA[Brain Stem]]></kwd>
<kwd lng="en"><![CDATA[Sodium]]></kwd>
<kwd lng="en"><![CDATA[Pregnant women]]></kwd>
<kwd lng="en"><![CDATA[Old Indegenous Woman]]></kwd>
<kwd lng="en"><![CDATA[Colombian]]></kwd>
<kwd lng="en"><![CDATA[Aphasia]]></kwd>
<kwd lng="en"><![CDATA[Hyperemesis gravidarum]]></kwd>
<kwd lng="en"><![CDATA[Hyponatremia]]></kwd>
<kwd lng="en"><![CDATA[Eclampsia]]></kwd>
</kwd-group>
</article-meta>
</front><back>
<ref-list>
<ref id="B1">
<label>1</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Corona]]></surname>
<given-names><![CDATA[G]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[A case of osmotic demyelination syndrome occurred after the correction of severe hyponatraemia in hyperemesis gravidarum]]></article-title>
<source><![CDATA[BMC Endocr Disord]]></source>
<year>2014</year>
<volume>14</volume>
<page-range>34</page-range></nlm-citation>
</ref>
<ref id="B2">
<label>2</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Martin]]></surname>
<given-names><![CDATA[RJ.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Central pontine and extrapontine myelinolysis: the osmotic demyelination syndromes]]></article-title>
<source><![CDATA[J Neurol Neurosurg Psychiatry]]></source>
<year>2004</year>
<volume>75</volume>
<numero>^s3</numero>
<issue>^s3</issue>
<supplement>3</supplement>
<page-range>iii22-8</page-range></nlm-citation>
</ref>
<ref id="B3">
<label>3</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Norenberg]]></surname>
<given-names><![CDATA[MD.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Central pontine myelinolysis: Historical and mechanistic considerations]]></article-title>
<source><![CDATA[Metab Brain Dis]]></source>
<year>2010</year>
<volume>25</volume>
<numero>1</numero>
<issue>1</issue>
<page-range>97-106</page-range></nlm-citation>
</ref>
<ref id="B4">
<label>4</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Lambeck]]></surname>
<given-names><![CDATA[J]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Central pontine myelinosis and osmotic demyelination syndrome]]></article-title>
<source><![CDATA[Dtsch Arztebl Int]]></source>
<year>2019</year>
<volume>116</volume>
<numero>35-36</numero>
<issue>35-36</issue>
<page-range>600-6</page-range></nlm-citation>
</ref>
<ref id="B5">
<label>5</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Ismail]]></surname>
<given-names><![CDATA[SK]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Review on hyperemesis gravidarum]]></article-title>
<source><![CDATA[Best Pract Res Clin Gastroenterol]]></source>
<year>2007</year>
<volume>21</volume>
<numero>5</numero>
<issue>5</issue>
<page-range>755-69</page-range></nlm-citation>
</ref>
<ref id="B6">
<label>6</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Anand]]></surname>
<given-names><![CDATA[K]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Rare complication of hyperemesis gravidarum-central pontine myelinolysis, A case report]]></article-title>
<source><![CDATA[J Gynecol]]></source>
<year>2017</year>
<volume>2</volume>
<numero>2</numero>
<issue>2</issue>
<page-range>000138</page-range></nlm-citation>
</ref>
<ref id="B7">
<label>7</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Mayner-Tresol]]></surname>
<given-names><![CDATA[G]]></given-names>
</name>
<name>
<surname><![CDATA[Reyna-Villasmil]]></surname>
<given-names><![CDATA[E.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Mielinólisis central pontina como complicación de hiperemesis gravídica]]></article-title>
<source><![CDATA[Rev. Peru. Ginecol. Obstet]]></source>
<year>2018</year>
<volume>64</volume>
<numero>3</numero>
<issue>3</issue>
<page-range>469-72</page-range></nlm-citation>
</ref>
<ref id="B8">
<label>8</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Sánchez-Ferrer]]></surname>
<given-names><![CDATA[ML]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Central pontine myelinolysis during pregnancy: Pathogenesis, diagnosis and management]]></article-title>
<source><![CDATA[J Obstet Gynaecol. (Lahore)]]></source>
<year>2017</year>
<volume>37</volume>
<numero>3</numero>
<issue>3</issue>
<page-range>273-9</page-range></nlm-citation>
</ref>
<ref id="B9">
<label>9</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Janga]]></surname>
<given-names><![CDATA[KC]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[A rare case of central pontine myelinolysis in overcorrection of hyponatremia with total parenteral nutrition in pregnancy]]></article-title>
<source><![CDATA[Case Rep Nephrol]]></source>
<year>2015</year>
<page-range>940807</page-range></nlm-citation>
</ref>
<ref id="B10">
<label>10</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Haro]]></surname>
<given-names><![CDATA[K]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Hiperemesis gravídica: manejo y consecuencias nutricionales; reporte de caso y revisión de literatura]]></article-title>
<source><![CDATA[Nutr. Hosp]]></source>
<year>2015</year>
<volume>31</volume>
<numero>2</numero>
<issue>2</issue>
</nlm-citation>
</ref>
<ref id="B11">
<label>11</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Fernández-Cué]]></surname>
<given-names><![CDATA[L.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Desmielinización osmótica pontina y extrapontina durante un puerperio complicado]]></article-title>
<source><![CDATA[Rev Cubana Med]]></source>
<year>2018</year>
<volume>57</volume>
<page-range>32-7</page-range></nlm-citation>
</ref>
<ref id="B12">
<label>12</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Perikal]]></surname>
<given-names><![CDATA[PJ]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Extrapontine myelinolysis and reversible parkinsonism after hyponatremia correction in a case of pituitary adenoma: hypopituitarism as a predisposition for osmotic demyelination]]></article-title>
<source><![CDATA[World Neurosurg]]></source>
<year>2018</year>
<volume>118</volume>
<page-range>304-10</page-range></nlm-citation>
</ref>
<ref id="B13">
<label>13</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Serrano-Castro]]></surname>
<given-names><![CDATA[PJ]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Possible case of peripheral osmotic demyelination syndrome]]></article-title>
<source><![CDATA[J Neurol Neurosurg Psychiatry]]></source>
<year>2008</year>
<volume>79</volume>
<numero>3</numero>
<issue>3</issue>
<page-range>331-2</page-range></nlm-citation>
</ref>
<ref id="B14">
<label>14</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Patil]]></surname>
<given-names><![CDATA[V]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Central pontine/extrapontine myelinolysis presenting with manic and catatonic symptoms]]></article-title>
<source><![CDATA[Indian J Psychol Med]]></source>
<year>2019</year>
<volume>41</volume>
<numero>5</numero>
<issue>5</issue>
<page-range>491-3</page-range></nlm-citation>
</ref>
<ref id="B15">
<label>15</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Goggin]]></surname>
<given-names><![CDATA[R]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Central pontine myelinolysis-induced mania: A case study]]></article-title>
<source><![CDATA[Asian J Psychiatr]]></source>
<year>2015</year>
<volume>14</volume>
<page-range>73-4</page-range></nlm-citation>
</ref>
<ref id="B16">
<label>16</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Jarrín]]></surname>
<given-names><![CDATA[S]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Mielinólisis extrapontina secundaria a hiponatremia por crisis adrenal]]></article-title>
<source><![CDATA[Rev Ecuat Neurol]]></source>
<year>2015</year>
<volume>24</volume>
<numero>1-3</numero>
<issue>1-3</issue>
<page-range>45-7</page-range></nlm-citation>
</ref>
<ref id="B17">
<label>17</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Delgado-Martínez]]></surname>
<given-names><![CDATA[F.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Primum non nocere: síndrome de desmielinización osmótica]]></article-title>
<source><![CDATA[An Radiol Méx]]></source>
<year>2019</year>
<volume>18</volume>
<page-range>126-34</page-range></nlm-citation>
</ref>
<ref id="B18">
<label>18</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Mangala]]></surname>
<given-names><![CDATA[G]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Acute psychosis as main manifestation of central pontine myelinolysis]]></article-title>
<source><![CDATA[Case Rep Neurol Med]]></source>
<year>2017</year>
<volume>2017</volume>
<page-range>1471096</page-range></nlm-citation>
</ref>
<ref id="B19">
<label>19</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Madhav]]></surname>
<given-names><![CDATA[Kamath]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Idiopathic central pontine and extrapontine myelinolysis in a child]]></article-title>
<source><![CDATA[J Pediatr Neurosci]]></source>
<year>2019</year>
<volume>14</volume>
<numero>2</numero>
<issue>2</issue>
<page-range>97-9</page-range></nlm-citation>
</ref>
<ref id="B20">
<label>20</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Madinaveitia-Turcott]]></surname>
<given-names><![CDATA[J]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Mielinólisis central y periférica de la protuberancia: presentación de un caso y revisión de la literatura]]></article-title>
<source><![CDATA[Rev Fac Med (Méx)]]></source>
<year>2014</year>
<volume>57</volume>
<page-range>25-30</page-range></nlm-citation>
</ref>
<ref id="B21">
<label>21</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Babanrao]]></surname>
<given-names><![CDATA[SA]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Osmotic myelinolysis: Does extrapontine myelinolysis precede central pontine myelinolysis? Report of two cases and review of literature]]></article-title>
<source><![CDATA[Indian J Radiol Imaging]]></source>
<year>2015</year>
<volume>25</volume>
<numero>2</numero>
<issue>2</issue>
<page-range>177-83</page-range></nlm-citation>
</ref>
<ref id="B22">
<label>22</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Sekhar]]></surname>
<given-names><![CDATA[KS]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[A rare case of Wernicke&#8217;s encephalopathy and central pontine myelinolysis induced by hyperemesis gravidarum]]></article-title>
<source><![CDATA[Eurorad]]></source>
<year>2014</year>
</nlm-citation>
</ref>
<ref id="B23">
<label>23</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Spasovski]]></surname>
<given-names><![CDATA[G]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Clinical practice guideline on diagnosis and treatment of hyponatraemia]]></article-title>
<source><![CDATA[Nephrol Dialysis Transplant]]></source>
<year>2014</year>
<volume>29</volume>
<numero>^s2</numero>
<issue>^s2</issue>
<supplement>2</supplement>
<page-range>i1-i39</page-range></nlm-citation>
</ref>
<ref id="B24">
<label>24</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Sterns]]></surname>
<given-names><![CDATA[RH.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Treatment of severe hyponatremia]]></article-title>
<source><![CDATA[Clin J Am Soc Nephrol]]></source>
<year>2018</year>
<volume>13</volume>
<numero>4</numero>
<issue>4</issue>
<page-range>641-9</page-range></nlm-citation>
</ref>
<ref id="B25">
<label>25</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Verbalis]]></surname>
<given-names><![CDATA[JG]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Diagnosis, evaluation, and treatment of hyponatremia: expert panel recommendations]]></article-title>
<source><![CDATA[Am J Med]]></source>
<year>2013</year>
<volume>126</volume>
<numero>^s1</numero>
<issue>^s1</issue>
<supplement>1</supplement>
<page-range>S1-42</page-range></nlm-citation>
</ref>
<ref id="B26">
<label>26</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Micieli]]></surname>
<given-names><![CDATA[A]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Central pontine (and extrapontine) myelinolysis despite appropriate sodium correction]]></article-title>
<source><![CDATA[Pract Neurol]]></source>
<year>2020</year>
<volume>20</volume>
<numero>1</numero>
<issue>1</issue>
<page-range>64-5</page-range></nlm-citation>
</ref>
<ref id="B27">
<label>27</label><nlm-citation citation-type="">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Jarraya]]></surname>
<given-names><![CDATA[A]]></given-names>
</name>
<name>
<surname><![CDATA[case]]></surname>
<given-names><![CDATA[Hyperemesis]]></given-names>
</name>
</person-group>
<source><![CDATA[Pan Afr Med J]]></source>
<year>2015</year>
<volume>20</volume>
<page-range>264-6</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
