<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0300-9041</journal-id>
<journal-title><![CDATA[Ginecología y obstetricia de México]]></journal-title>
<abbrev-journal-title><![CDATA[Ginecol. obstet. Méx.]]></abbrev-journal-title>
<issn>0300-9041</issn>
<publisher>
<publisher-name><![CDATA[Federación Mexicana de Colegios de Obstetricia y Ginecología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0300-90412019001200009</article-id>
<article-id pub-id-type="doi">10.24245/gom.v87i12.3265</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Queratosis seborreica en el fondo de saco de Douglas: reporte de un caso]]></article-title>
<article-title xml:lang="en"><![CDATA[Seborrheic keratoses in the recto-uterine pouch: Case report]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gómez-Londoño]]></surname>
<given-names><![CDATA[Mauricio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Echavarría-Restrepo]]></surname>
<given-names><![CDATA[Luís Guillermo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gutiérrez-Sanmartín]]></surname>
<given-names><![CDATA[Joan Manuel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Merino-Correa]]></surname>
<given-names><![CDATA[Sara Catalina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Henao]]></surname>
<given-names><![CDATA[Claudia Patricia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sanín-Ramírez]]></surname>
<given-names><![CDATA[Daniel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Clínica Universitaria Bolivariana  ]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Clínica Universitaria Bolivariana  ]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad de Valencia  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Spain</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Ginecología y Obstetricia  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="Af5">
<institution><![CDATA[,Clínica Universitaria Bolivariana servio de Uroginecología y piso pélvico femenino ]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2019</year>
</pub-date>
<volume>87</volume>
<numero>12</numero>
<fpage>842</fpage>
<lpage>845</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0300-90412019001200009&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0300-90412019001200009&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0300-90412019001200009&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  ANTECEDENTES:  Existen pocos reportes de neoplasias epiteliales con apariencia escamosa originadas en el cuello uterino o la vagina. Estas lesiones se clasifican, por su similitud morfológica, en lesiones similares a queratosis seborreica. Cuando ésta aparece en la mucosa de la vulva o vagina debe establecerse la diferenciación con lesiones intraepiteliales escamosas de bajo y alto grado.  OBJETIVO:  Describir un caso de queratosis seborreica en el saco de Douglas.  CASO CLÍNICO:  Paciente de 70 años, con pérdida involuntaria de orina con los esfuerzos; se le colocó una cinta suburetral para resolver este problema. Durante el procedimiento se detectó una lesión en la mucosa vaginal, a las seis del reloj, en el fondo del saco de Douglas, de 1.2 x 1 cm, color pardo y consistencia blanda. Durante el procedimiento se tomó una muestra para estudio histopatológico que se reportó como: epidermis con marcada hiperqueratosis, acantosis regular, ensanchamiento y anastomosis de las crestas con formación de perlas córneas, dermis con infiltrado inflamatorio crónico perivascular, negativo para malignidad. Se estableció el diagnóstico de queratosis seborreica hipertrófica, positiva para tinción de P16 que orientó a infección de virus del papiloma. El tratamiento fue: escisión con evolución satisfactoria y seguimiento.  CONCLUSIONES:  La queratosis seborreica en el fondo de saco de Douglas se reporta de manera excepcional, su comportamiento es benigno y casi siempre se asocia con tipos de virus del papiloma humano de bajo riesgo.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  BACKGROUND:  Thera are few repots of intraepithelial neoplasms with origins in the cervix or vagina with squamous appearance. This kind of lesions have been classified because of their morphologic similarities, in the category of &#8220;seborrheic keratoses like&#8221;. When seborrheic keratoses appears in the vaginal or vulvar mucosa, it has to be differentiated from low and high grade intraepithelial squamous lesions.  OBJECTIVE:  To describe a case of seborrheic keratoses in the recto-uterine pouch.  CLINICAL CASE:  70 years old patient, who underwent surgery for stress urinary incontinence with a sub-urethral sling. During the procedure, a lesion in the vaginal mucosa was detected, specifically in the recto-uterine pouch, of 1.2 x 1 cm length, with a light brown color and soft consistency. A specimen was taken from the lesion during the procedure for histopathological study, which reported: hyperkeratosis in the epidermis, regular acanthosis, thickening and anastomosis of the crests with formation of corneal pearls, dermis with inflammatory, chronic, perivascular infiltration, with no signs of malignancy. The diagnosis was hypertrophic seborrheic keratoses, positive for P16 stain which orients to HPV infection. The lesion was removed and the patient continued follow up with her primary care provider.  CONCLUSIONS:  Seborrheic keratoses in this location is uncommon, with few reports in literature. These lesions are usually benign and are associated to HPV of low risk.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Neoplasias intraepiteliales]]></kwd>
<kwd lng="es"><![CDATA[cuello uterino]]></kwd>
<kwd lng="es"><![CDATA[vagina escamosa]]></kwd>
<kwd lng="es"><![CDATA[queratosis seborreica]]></kwd>
<kwd lng="es"><![CDATA[mucosa vulvar]]></kwd>
<kwd lng="es"><![CDATA[mucosa vaginal]]></kwd>
<kwd lng="es"><![CDATA[infección virus del papiloma]]></kwd>
<kwd lng="es"><![CDATA[lesiones escamosas intraepiteliales del cuello uterino]]></kwd>
<kwd lng="es"><![CDATA[incontinencia urinaria de esfuerzo]]></kwd>
<kwd lng="en"><![CDATA[Intraephitelial neoplasms]]></kwd>
<kwd lng="en"><![CDATA[Cervix]]></kwd>
<kwd lng="en"><![CDATA[Vagina]]></kwd>
<kwd lng="en"><![CDATA[Squamous]]></kwd>
<kwd lng="en"><![CDATA[Keratosis]]></kwd>
<kwd lng="en"><![CDATA[Seborrheic]]></kwd>
<kwd lng="en"><![CDATA[Vulvar mucosa]]></kwd>
<kwd lng="en"><![CDATA[Vaginal mucosa]]></kwd>
<kwd lng="en"><![CDATA[Papillomavirus infection: Squamous Intraephitelial Lesions of the Cervix]]></kwd>
<kwd lng="en"><![CDATA[Urinary Incontinence Stress]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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