<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0300-9041</journal-id>
<journal-title><![CDATA[Ginecología y obstetricia de México]]></journal-title>
<abbrev-journal-title><![CDATA[Ginecol. obstet. Méx.]]></abbrev-journal-title>
<issn>0300-9041</issn>
<publisher>
<publisher-name><![CDATA[Federación Mexicana de Colegios de Obstetricia y Ginecología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0300-90412018001100744</article-id>
<article-id pub-id-type="doi">10.24245/gom.v86i11.2185</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Hipertrigliceridemia familiar severa en el embarazo: tratamiento con plasmaféresis. Reporte de un caso y revisión de la bibliografía]]></article-title>
<article-title xml:lang="en"><![CDATA[Severe familial hypertriglyceridemia: management with plasmapheresis. Case report and literature review]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Burgos-Luna]]></surname>
<given-names><![CDATA[Juan Manuel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Cortés-Castillo]]></surname>
<given-names><![CDATA[Valeria]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Fernández-Pérez]]></surname>
<given-names><![CDATA[Paula Andrea]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Escobar-Vidarte]]></surname>
<given-names><![CDATA[María Fernanda]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Fundación Valle del Lili Unidad de Alta Complejidad Obstétrica ]]></institution>
<addr-line><![CDATA[Cali ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Fundación Valle del Lili Unidad de Alta Complejidad Obstétrica ]]></institution>
<addr-line><![CDATA[Cali ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Fundación Valle del Lili Unidad de Alta Complejidad Obstétrica ]]></institution>
<addr-line><![CDATA[Cali ]]></addr-line>
<country>Colombia</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2018</year>
</pub-date>
<volume>86</volume>
<numero>11</numero>
<fpage>744</fpage>
<lpage>748</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0300-90412018001100744&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0300-90412018001100744&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0300-90412018001100744&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  ANTECEDENTES: Durante el embarazo suceden cambios adaptativos, secundarios a las variaciones hormonales, como las alteraciones en la concentración de lípidos plasmáticos necesarias para garantizar la adecuada nutrición al feto. Algunas veces la concentración de triglicéridos sobrepasa los límites de tolerancia y ello pone en riesgo la salud de la madre.  CASO CLÍNICO: Paciente con antecedente de un embarazo, hipertrigliceridemia familiar que se exacerbó por los procesos fisiológicos del embarazo. Se hospitalizó para tratarla y los especialistas en Nutrición y Endocrinología le indicaron fármacos y plasmaféresis.  CONCLUSIONES: La plasmaféresis es un método efectivo después de seis sesiones de tratamiento con el que se logran reducir 70% las concentraciones séricas triglicéridos, aunque no fue una medida definitiva y se requirió finalizar el embarazo.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  BACKGROUND: Adaptive changes occur in pregnancy, secondary to hormonal variations, one of which is alterations in the level of plasma lipids that aims to ensure adequate nutrition to the fetus. However, sometimes triglycerides reach such high levels that they could compromise maternal health.  CLINICAL CASE: The case of a female patient with a history of familial hypertriglyceridemia, exacerbated by the physiological processes of pregnancy, is presented. It was managed intrahospitalary, followed by nutrition and endocrinology, in addition to the use of pharmacological treatment and plasmapheresis.  CONCLUSIONS: The use of plasmapheresis was evaluated as a therapeutic measure, where it was found to be an equally effective method after 6 sessions of treatment, achieving a 70% reduction in serum levels of triglycerides, however it was not a definitive measure and it was necessary to end the pregnancy.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Embarazo]]></kwd>
<kwd lng="es"><![CDATA[plasmaféresis]]></kwd>
<kwd lng="es"><![CDATA[hipertrigliceridemia familiar]]></kwd>
<kwd lng="es"><![CDATA[feto]]></kwd>
<kwd lng="es"><![CDATA[estado nutricional]]></kwd>
<kwd lng="en"><![CDATA[Pregnancy]]></kwd>
<kwd lng="en"><![CDATA[Plasmapheresis]]></kwd>
<kwd lng="en"><![CDATA[Familial hypertriglyceridemia]]></kwd>
<kwd lng="en"><![CDATA[Fetus]]></kwd>
<kwd lng="en"><![CDATA[Nutritional status]]></kwd>
</kwd-group>
</article-meta>
</front><back>
<ref-list>
<ref id="B1">
<label>1</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Basaran]]></surname>
<given-names><![CDATA[A]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Pregnancy-induced hyperlipoproteinemia Review of the literature]]></article-title>
<source><![CDATA[Reprod Sci]]></source>
<year>2009</year>
<volume>16</volume>
<page-range>431-7</page-range></nlm-citation>
</ref>
<ref id="B2">
<label>2</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Torres]]></surname>
<given-names><![CDATA[CJ]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Pancreatitis hipertrigliceridémica durante el embarazo Comunicación de un caso]]></article-title>
<source><![CDATA[Ginecol Obstet Mex]]></source>
<year>2006</year>
<volume>74</volume>
<page-range>170-6</page-range></nlm-citation>
</ref>
<ref id="B3">
<label>3</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Alvarez]]></surname>
<given-names><![CDATA[JJ]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Longitudinal study on lipoprotein profile, high density lipoprotein subclass, and postheparin lipases during gestation in women]]></article-title>
<source><![CDATA[J Lipid Res]]></source>
<year>1996</year>
<volume>37</volume>
<page-range>299-308</page-range></nlm-citation>
</ref>
<ref id="B4">
<label>4</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Herrera]]></surname>
<given-names><![CDATA[H]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Maternal lipid metabolism during normal pregnancy and its implications to fetal development]]></article-title>
<source><![CDATA[Clinical Lipidology]]></source>
<year>2017</year>
<volume>5</volume>
<page-range>899-911</page-range></nlm-citation>
</ref>
<ref id="B5">
<label>5</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Goldberg]]></surname>
<given-names><![CDATA[AS]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Severe hypertriglyceridemia in pregnancy]]></article-title>
<source><![CDATA[J Clin Endocrinol Metab]]></source>
<year>2012</year>
<volume>97</volume>
<page-range>2589-96</page-range></nlm-citation>
</ref>
<ref id="B6">
<label>6</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Hegele]]></surname>
<given-names><![CDATA[RA]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[The polygenic nature of hypertriglyceridemia: implicactions for definition.diagnosis.and management]]></article-title>
<source><![CDATA[Lancet Diabetes Endocrinol]]></source>
<year>2014</year>
<volume>2</volume>
<numero>8</numero>
<issue>8</issue>
<page-range>655-66</page-range></nlm-citation>
</ref>
<ref id="B7">
<label>7</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Muntajib]]></surname>
<given-names><![CDATA[SA]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Role of therapeutic plasma Exchange in the treatment of severe hypertriglyceridemia an experience]]></article-title>
<source><![CDATA[Ther Adv Endocrinol Metab]]></source>
<year>2017</year>
<volume>8</volume>
<numero>12</numero>
<issue>12</issue>
<page-range>169-72</page-range></nlm-citation>
</ref>
<ref id="B8">
<label>8</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Basar]]></surname>
<given-names><![CDATA[R]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Therapeutic apheresis for severe hypertriglyceridemia in pregnancy]]></article-title>
<source><![CDATA[Arch Gynecol Obstet]]></source>
<year>2013</year>
<volume>287</volume>
<numero>5</numero>
<issue>5</issue>
<page-range>839-43</page-range></nlm-citation>
</ref>
<ref id="B9">
<label>9</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Rosales]]></surname>
<given-names><![CDATA[E]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Hipertrigliceridemia familiar y embarazo Reporte de dos casos]]></article-title>
<source><![CDATA[Ginecol Obstet Mex]]></source>
<year>2016</year>
<volume>84</volume>
<numero>10</numero>
<issue>10</issue>
<page-range>668-73</page-range></nlm-citation>
</ref>
<ref id="B10">
<label>10</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Gök]]></surname>
<given-names><![CDATA[F]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Acute Pancreatitis Due Hypertriglyceridemia in Pregnancy]]></article-title>
<source><![CDATA[Turk J Anaesthesiol Reanim]]></source>
<year>2015</year>
<volume>43</volume>
<numero>2</numero>
<issue>2</issue>
<page-range>116-8</page-range></nlm-citation>
</ref>
<ref id="B11">
<label>11</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Geng]]></surname>
<given-names><![CDATA[Y]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Severe acute pancreatitis during pregnancy: eleven years experience from surgical intensive care unit]]></article-title>
<source><![CDATA[Dig Dis Sci]]></source>
<year>2011</year>
<volume>56</volume>
<numero>12</numero>
<issue>12</issue>
<page-range>3672-7</page-range></nlm-citation>
</ref>
<ref id="B12">
<label>12</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Wong]]></surname>
<given-names><![CDATA[B]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Severe gestational hypertriglyceridemia A practical approach for clinicians]]></article-title>
<source><![CDATA[Obstet Med]]></source>
<year>2015</year>
<volume>8</volume>
<numero>4</numero>
<issue>4</issue>
<page-range>158-67</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
