<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0188-4999</journal-id>
<journal-title><![CDATA[Revista internacional de contaminación ambiental]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Int. Contam. Ambient]]></abbrev-journal-title>
<issn>0188-4999</issn>
<publisher>
<publisher-name><![CDATA[Universidad Nacional Autónoma de México, Instituto de Ciencias de la Atmósfera y Cambio Climático]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0188-49992023000100110</article-id>
<article-id pub-id-type="doi">10.20937/rica.54549</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[A simple tool to assess the effect of water-soluble soil pollutants on enzyme activity in human whole blood samples using WST-1 assay]]></article-title>
<article-title xml:lang="es"><![CDATA[Una herramienta sencilla para evaluar el efecto de los contaminantes del suelo solubles en agua sobre la actividad enzimática en muestras de sangre humana entera utilizando el ensayo WST-1]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Koleva]]></surname>
<given-names><![CDATA[Vanya]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Koynova]]></surname>
<given-names><![CDATA[Teodora]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Kuleva]]></surname>
<given-names><![CDATA[Ivaila]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Dragoeva]]></surname>
<given-names><![CDATA[Asya]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Konstantin Preslavsky University of Shumen Department of Biology ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Bulgaria</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,&#1052;edical University Prof. Dr. Paraskev Stoyanov Department of Biology ]]></institution>
<addr-line><![CDATA[Varna ]]></addr-line>
<country>Bulgaria</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2023</year>
</pub-date>
<volume>39</volume>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0188-49992023000100110&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0188-49992023000100110&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0188-49992023000100110&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT Hazardous compounds accumulated in soil affect soil quality. Here we show that WST-1 can be used for evaluation of the effect of water soil extracts on enzyme activity in human whole-blood samples. Soil samples from the Shumen Plateau Nature Park (NP) and the City Park in Shumen (SCP) were studied. We observed significant differences between control and treated whole-blood samples. These results indicated that soil water extracts affected normal metabolic activity. In conclusion, the WST-1 assay can be used for biomonitoring soil quality. The presence of harmful water-soluble compounds in tested soils may pose a risk to ecosystems and human health.]]></p></abstract>
<abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN Los compuestos peligrosos acumulados en el suelo afectan la calidad del suelo. Aquí mostramos que WST-1 se puede utilizar para evaluar el efecto de los extractos de agua y suelo sobre la actividad enzimática en muestras de sangre entera humana. Se estudiaron muestras de suelo de Shumen Plateau Nature Park (NP) y City Park en Shumen (SCP). Observamos diferencias significativas entre las muestras de sangre entera tratadas y de control. Estos resultados indicaron que los extractos de agua del suelo afectaron la actividad metabólica normal. En conclusión, el ensayo WST-1 se puede utilizar para el biomonitoreo de la calidad del suelo. La presencia de compuestos solubles en agua nocivos en los suelos analizados puede representar un riesgo para los ecosistemas y la salud humana.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[hazardous compounds]]></kwd>
<kwd lng="en"><![CDATA[water soil extracts]]></kwd>
<kwd lng="en"><![CDATA[tetrazolium salts]]></kwd>
<kwd lng="en"><![CDATA[environmental biomonitoring]]></kwd>
<kwd lng="es"><![CDATA[compuestos peligrosos]]></kwd>
<kwd lng="es"><![CDATA[extractos de agua y suelo]]></kwd>
<kwd lng="es"><![CDATA[sales de tetrazolio]]></kwd>
<kwd lng="es"><![CDATA[biomonitoreo ambiental]]></kwd>
</kwd-group>
</article-meta>
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<given-names><![CDATA[M.J.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Clinical effects of chemical exposures on mitochondrial function]]></article-title>
<source><![CDATA[Toxicology]]></source>
<year>2017</year>
<volume>391</volume>
<page-range>90-9</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
