<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0187-5337</journal-id>
<journal-title><![CDATA[Perinatología y reproducción humana]]></journal-title>
<abbrev-journal-title><![CDATA[Perinatol. Reprod. Hum.]]></abbrev-journal-title>
<issn>0187-5337</issn>
<publisher>
<publisher-name><![CDATA[Instituto Nacional de Perinatología]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0187-53372023000200084</article-id>
<article-id pub-id-type="doi">10.24875/per.23000010</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Evaluación prenatal del síndrome de heterotaxia por ecografía fetal]]></article-title>
<article-title xml:lang="en"><![CDATA[Prenatal assessment of heterotaxy syndrome by fetal ultrasound]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Santiago-Sanabria]]></surname>
<given-names><![CDATA[Leopoldo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Morales-Martínez]]></surname>
<given-names><![CDATA[Óscar G.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Alonso-León]]></surname>
<given-names><![CDATA[Marco C.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sanabria-Villegas]]></surname>
<given-names><![CDATA[L. del Carmen]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ignacio-García]]></surname>
<given-names><![CDATA[Melissa G.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Flores-Gutiérrez]]></surname>
<given-names><![CDATA[Everardo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
<xref ref-type="aff" rid="A0"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sánchez-Alquicira]]></surname>
<given-names><![CDATA[Bernardo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Unidad Médica de Alta Especialidad 4 Luis Castelazo Ayala Departamento de Ginecología Oncológica y Patología Mamaria ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Univiersidad Nacional Autónoma de México Facultad de Medicina Servicio de Oncología Ginecológica]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital General de Huejotzingo Departamento de Ginecología y Obstetricia ]]></institution>
<addr-line><![CDATA[Puebla ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Secretaría de Salud del Estado de Puebla Unidad Tocoquirúrgica ]]></institution>
<addr-line><![CDATA[Huejotzingo ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af5">
<institution><![CDATA[,Hospital Ángeles Villahermosa Departamento de Ginecología y Obstetricia ]]></institution>
<addr-line><![CDATA[Villahermosa ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af6">
<institution><![CDATA[,Instituto Nacional de Perinatología Isidro Espinosa de los Reyes Servicio de Obstetricia ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af7">
<institution><![CDATA[,Hospital de la Mujer Departamento de Ginecología y Obstetricia ]]></institution>
<addr-line><![CDATA[Puebla ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af8">
<institution><![CDATA[,Secretaría de Salud del Estado de Puebla Servicio de Tococirugía ]]></institution>
<addr-line><![CDATA[Puebla ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af9">
<institution><![CDATA[,Centro Médico Nacional Siglo XXI Hospital de Pediatría Departamento de Pediatría]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<aff id="A10">
<institution><![CDATA[,Univiersidad Nacional Autónoma de México Servicio de Cardiología Pediátrica ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<aff id="A11">
<institution><![CDATA[,Universidad Panamericana Departamento de Ginecología y Obstetricia Facultad de Ciencias de la Salud]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2023</year>
</pub-date>
<volume>37</volume>
<numero>2</numero>
<fpage>84</fpage>
<lpage>89</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0187-53372023000200084&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0187-53372023000200084&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0187-53372023000200084&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen El síndrome de heterotaxia es una entidad de baja prevalencia, que tiene su origen durante el desarrollo embrionario, que afecta a diversos órganos y sistemas. Es por ello que su diagnóstico representa un reto durante la gestación. El pronóstico dependerá principalmente de las malformaciones cardiacas asociadas. Se presenta el caso de un paciente con diagnóstico de síndrome de heterotaxia durante el primer trimestre. Se detallan los patrones ecográficos obtenidos durante el tamizaje del primer trimestre que auxiliaron a integrar el diagnóstico de esta entidad, así como las anomalías cardiacas asociadas. El manejo debe contemplar a un equipo multidisciplinario, el cual brinde un manejo oportuno, que será principalmente quirúrgico, enfocado en las malformaciones cardiacas.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Heterotaxy syndrome is a low prevalence entity, which originates during embryonic development, affecting diverse organs and systems. That is why its diagnosis represents a challenge during pregnancy. The prognosis depends mainly on the associated cardiac malformations. The case of a patient with a diagnosis of heterotaxy syndrome during the first trimester is presented. The ultrasound patterns obtained during the first trimester screening that helped to integrate the diagnosis of this entity are detailed, as well as the associated cardiac anomalies. Management must contemplate a multidisciplinary team, which provides timely management, which will be mainly surgical, focused on cardiac malformations.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Síndrome de heterotaxia]]></kwd>
<kwd lng="es"><![CDATA[Ecocardiografía fetal]]></kwd>
<kwd lng="es"><![CDATA[Defecto cardiaco congénito]]></kwd>
<kwd lng="en"><![CDATA[Heterotaxy syndrome]]></kwd>
<kwd lng="en"><![CDATA[Fetal echocardiography]]></kwd>
<kwd lng="en"><![CDATA[Congenital heart defect]]></kwd>
</kwd-group>
</article-meta>
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