0186-4866 0186-4866 S0186-48662019000100061 10.24245/mim.v35i1.2212 Mexico Mexico 00 02 2019 00 02 2019 35 1 61 79

1 2013 15 1 1 1-26 2 2005 366 1773-83 3 2014 129 e28-e292 4 2008 3 2 2 105-16 5 2008 24 2 2 98-103 6 2011 12 5 5 224-34 7 2010 41 5 5 878-84 8 2011 12 5 5 235-41 9 1993 24 1 1 35-41 10 2014 3 4 4 11 2008 14 6 6 28-45 12 1982 32 871-6 13 2013 44 3 3 870-947 14 1999 33 4 4 373-8 15 2000 31 71-6 16 1994 25 11 11 2220-6 17 2018 49 3 3 e46-e110 18 2005 76 1528-33 19 2004 292 1823-30 20 2014 72 309-16 21 2000 31 3067-78 22 National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group 1995 333 24 24 1581-7 23 2004 35 10 10 2418-24 24 2007 369 9558 9558 275-82 25 2008 359 13 13 1317-29 26 2009 40 7 7 2433-7 27 2010 9 9 9 866-74 28 2010 375 9727 9727 1695-703 29 2011 364 22 22 2138-46 30 1999 282 21 21 2003-11 31 2007 38 10 10 2633-9 32 2010 41 5 5 932-7 33 2015 372 1 1 11-20 34 2015 313 14 14 1451-62 35 2016 67 22 22 2631-44 36 2016 43 455-46 37 2016 353 i1754 38 2012 380 9849 9849 1231-40 39 2000 31 1240-9 40 ESPRIT Study Group 2006 367 1665-73 41 2002 33 1934-42 42 2007 369 1347-55 43 2012 141 2 2 e601S-36S 44 2011 10 357-71 45 2010 28 863-86 46 2012 18 2 2 132-8 47 2003 34 2208-14 48 2001 32 1330-5 49 2001 57 200-6 50 2002 33 136-40 51 2004 35 539-43 52 2007 13 2 2 175-9 53 2012 1 14-20 54 2004 351 2170-8 55 2012 32 1 1 56 2012 10 Art 57 2017 48 00 58 2008 52 S27-39 59 2011 42 1 1 227-76 60 2012 366 1914-22 61 Heart Protection Study Collaborative Group 2004 363 757-67 62 The SPARCL Investigators 2006 355 549-59 63 CREST investigators 2010 363 11-23 64 2004 351 1493-501 65 2010 9 10 10 959-68 66 2002 324 699-702 67 2004 35 116-21