<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0186-4866</journal-id>
<journal-title><![CDATA[Medicina interna de México]]></journal-title>
<abbrev-journal-title><![CDATA[Med. interna Méx.]]></abbrev-journal-title>
<issn>0186-4866</issn>
<publisher>
<publisher-name><![CDATA[Edición y Farmacia S.A. de C.V.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0186-48662018000500012</article-id>
<article-id pub-id-type="doi">10.24245/mim.v34i5.1971</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Prescripción racional de antibióticos: una conducta urgente]]></article-title>
<article-title xml:lang="en"><![CDATA[Rational prescription of antibiotics: an urgent conduct.]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Isaías-Camacho]]></surname>
<given-names><![CDATA[Jorge O]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Salinas-Lezama]]></surname>
<given-names><![CDATA[Erika]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez-Weber]]></surname>
<given-names><![CDATA[Federico Leopoldo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Díaz-Greene]]></surname>
<given-names><![CDATA[Enrique]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Ángeles Pedregal  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad La Salle Facultad Mexicana de Medicina ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad La Salle  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>10</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>10</month>
<year>2018</year>
</pub-date>
<volume>34</volume>
<numero>5</numero>
<fpage>762</fpage>
<lpage>770</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0186-48662018000500012&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0186-48662018000500012&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0186-48662018000500012&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: Los antibióticos han revolucionado la forma de ver y practicar la medicina. Gracias a su existencia millones de vidas se han salvado a lo largo de la historia. Sin embargo, en el siglo XXI surge un tema que es de vital importancia atender: la resistencia antimicrobiana. La resistencia antimicrobiana amenaza el futuro de lo que alguna vez fue cura de muchas enfermedades mortales y representa un reto actual para todo el profesional de la salud. La resistencia antimicrobiana no es un tema que haya surgido recientemente, pero la cantidad de resistencia a organismos, las ubicaciones geográficas afectadas por la resistencia a los medicamentos y la amplitud de la resistencia en organismos individuales están aumentando de forma acelerada. Existen más de 15 clases de antibióticos cuyos mecanismos de acción están implicados en funciones fisiológicas o metabólicas esenciales del microorganismo. De los anteriores, ninguno ha escapado de algún mecanismo de resistencia.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: Antibiotic therapy has been a revolutionary way of seeing and practicing medicine. Regarding to its existence, millions of lives have been saved throughout history. Nevertheless, nowadays a vital topic is emerging: antibiotic resistance. Antibiotic resistance threatens the future of what once was the cure for a lot of many deadly diseases and now represents a challenge for all healthcare professionals. Antibiotic resistance is not a new concept, but the amount of resistant bacteria to certain antibiotics, geographical changes and locations affected with antibiotic resistance and broad-spectrum resistance is currently quickly increasing. There are more than fifteen antibiotic families whose mechanisms of action are involved in basic physiological and metabolic features of different bacteria. Of none of the latter has escaped any antibiotic.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Antibióticos]]></kwd>
<kwd lng="es"><![CDATA[resistencia antibiótica]]></kwd>
<kwd lng="en"><![CDATA[Antibiotic]]></kwd>
<kwd lng="en"><![CDATA[Antibiotic resistance]]></kwd>
</kwd-group>
</article-meta>
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