<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0186-4866</journal-id>
<journal-title><![CDATA[Medicina interna de México]]></journal-title>
<abbrev-journal-title><![CDATA[Med. interna Méx.]]></abbrev-journal-title>
<issn>0186-4866</issn>
<publisher>
<publisher-name><![CDATA[Edición y Farmacia S.A. de C.V.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0186-48662017000500696</article-id>
<article-id pub-id-type="doi">10.24245/mim.v33i5.1204</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Inmunosenescencia]]></article-title>
<article-title xml:lang="en"><![CDATA[Immunosenescence]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Barrera-Salas]]></surname>
<given-names><![CDATA[M.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Morales-Hernández]]></surname>
<given-names><![CDATA[AE.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Hernández-Osorio]]></surname>
<given-names><![CDATA[JJ.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Hernández-Salcedo]]></surname>
<given-names><![CDATA[DR.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Valencia-López]]></surname>
<given-names><![CDATA[R.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ramírez-Crescencio]]></surname>
<given-names><![CDATA[MA.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Ángeles Clínica Londres  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Ángeles Clínica Londres  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital Ángeles Clínica Londres  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
</aff>
<aff id="Af4">
<institution><![CDATA[,Hospital Ángeles Clínica Londres  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
</aff>
<aff id="Af5">
<institution><![CDATA[,Hospital Ángeles Clínica Londres  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
</aff>
<aff id="Af6">
<institution><![CDATA[,Hospital Ángeles Clínica Londres  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>10</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>10</month>
<year>2017</year>
</pub-date>
<volume>33</volume>
<numero>5</numero>
<fpage>696</fpage>
<lpage>704</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0186-48662017000500696&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0186-48662017000500696&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0186-48662017000500696&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen La inmunosenescencia se refiere a los cambios que se producen en el sistema inmunitario a causa del envejecimiento y que afectan la inmunidad innata y adaptativa. Estos cambios predisponen a padecer enfermedades infecciosas, cáncer, autoinmunidad y a respuestas escasas tras la administración de vacunas.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Immunosenescence refers to age-related changes in the immune system affecting both innate and adaptive immune response. These changes increase the susceptibility to infectious diseases, cancer and decreased vaccine efficacy.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[inmunosenescencia]]></kwd>
<kwd lng="es"><![CDATA[envejecimiento]]></kwd>
<kwd lng="es"><![CDATA[células T]]></kwd>
<kwd lng="en"><![CDATA[immunosenescence]]></kwd>
<kwd lng="en"><![CDATA[ageing]]></kwd>
<kwd lng="en"><![CDATA[T cells]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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