<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0028-3746</journal-id>
<journal-title><![CDATA[Neumología y cirugía de tórax]]></journal-title>
<abbrev-journal-title><![CDATA[Neumol. cir. torax]]></abbrev-journal-title>
<issn>0028-3746</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Mexicana de Neumología y Cirugía de Tórax; Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas; Sociedad Cubana de Neumología; Sociedad Paraguaya de Neumología; Sociedad Boliviana de Neumología.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0028-37462022000200086</article-id>
<article-id pub-id-type="doi">10.35366/108494</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Perfil clínico que facilita la sospecha de cáncer de pulmón para un diagnóstico oportuno]]></article-title>
<article-title xml:lang="en"><![CDATA[Clinical profile that facilitates the suspicion of lung cancer for a timely diagnosis]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Báez-Saldaña]]></surname>
<given-names><![CDATA[Renata]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Vargas-Rojas]]></surname>
<given-names><![CDATA[Alberto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Chavarría-Castro]]></surname>
<given-names><![CDATA[D. Yair]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rumbo-Nava]]></surname>
<given-names><![CDATA[Uriel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Contreras-Garza]]></surname>
<given-names><![CDATA[Belinda]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Guinto-Ramírez]]></surname>
<given-names><![CDATA[Paulina]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Arrieta]]></surname>
<given-names><![CDATA[Óscar]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Nacional Autónoma de México Facultad de Medicina ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Instituto Nacional de Cancerología  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>México</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2022</year>
</pub-date>
<volume>81</volume>
<numero>2</numero>
<fpage>86</fpage>
<lpage>93</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0028-37462022000200086&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0028-37462022000200086&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0028-37462022000200086&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen:  Introducción:  El cáncer de pulmón (CP) por lo general se diagnostica tardíamente. El entendimiento de cómo se presentan los pacientes al momento de su diagnóstico es útil para la identificación temprana de la enfermedad.  Objetivo:  Identificar el perfil clínico de pacientes con cáncer de pulmón que permita sospechar el diagnóstico y proponer un algoritmo para su referencia temprana.  Material y métodos:  Serie de casos prospectiva de cáncer de pulmón. Se estudiaron las características generales, tabaquismo, exposición a humo de leña, tiempo desde el inicio de síntomas al diagnóstico, y el tipo y frecuencia de los síntomas y se analizó su asociación con derrame pleural.  Resultados:  La mediana de la edad fue 65 años, 55% fueron hombres. Antecedente de tabaquismo 50.2%, exposición a humo de leña 43.9%. La mediana del tiempo desde el inicio de síntomas al diagnóstico fue de 120 días y en 94% éste fue de más de tres semanas. Los síntomas más frecuentes fueron tos 88%, tos por tres semanas o más 94.6%, disnea 75.2%, dolor torácico 50%, pérdida de peso 70%, hemoptisis 22%, derrame pleural neoplásico 44.9%. La presencia simultánea de disnea, dolor torácico y saturación de oxígeno &lt; 88% se asociaron a derrame pleural OR (IC 95%) 7.54 (3.28-17.34).  Conclusiones:  En pacientes adultos que refieran tos por tres semanas o más y/o cualquiera de los siguientes síntomas: disnea, dolor torácico, pérdida de peso, hemoptisis o fatiga que no se expliquen con base en un diagnóstico deberán evaluarse mediante una radiografía de tórax para su referencia temprana a una unidad especializada.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract:  Introduction:  Lung cancer (LC) is usually diagnosed late. Understanding how patients present at the time of their diagnosis it is useful for early identification of the disease.  Objective:  To identify the clinical profile of patients with lung cancer, allowing to suspect the diagnosis and to propose an algorithm for early referral.  Material and methods:  Prospective case series of lung cancer. The general characteristics, smoking, exposure to wood smoke, time from symptom onset to diagnosis and the type and frequency of symptoms were studied and their association with pleural effusion was analyzed.  Results:  The median age was 65 years, 55% were men. History of smoking 50.2%, exposure to wood smoke 43.9%. The median time from symptom onset to diagnosis was 120 days and in 94% it was more than 3 weeks. The most frequent symptoms were cough 88%, cough for 3 weeks or more 94.6%, dyspnea 75.2%, chest pain 50%, weight loss 70%, and hemoptysis 22%. Malignant pleural effusion 44.9%. Dyspnea, chest pain and oxygen saturation &lt; 88% simultaneously were associated with pleural effusion OR (95% CI) 7.54 (3.28-17.34).  Conclusions:  Adult patients who report cough for 3 weeks or more and/or any of the following symptoms: dyspnea, chest pain, weight loss, hemoptysis, or fatigue that are not explained by established diagnosis, should be evaluated by chest x-ray for early referral to a specialized unit.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[cáncer de pulmón]]></kwd>
<kwd lng="es"><![CDATA[síntomas]]></kwd>
<kwd lng="es"><![CDATA[diagnóstico]]></kwd>
<kwd lng="es"><![CDATA[derrame pleural]]></kwd>
<kwd lng="es"><![CDATA[diagnóstico temprano del cáncer de pulmón]]></kwd>
<kwd lng="en"><![CDATA[lung cancer]]></kwd>
<kwd lng="en"><![CDATA[symptoms]]></kwd>
<kwd lng="en"><![CDATA[diagnosis]]></kwd>
<kwd lng="en"><![CDATA[pleural effusion]]></kwd>
<kwd lng="en"><![CDATA[early diagnosis lung cancer]]></kwd>
</kwd-group>
</article-meta>
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