<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0028-3746</journal-id>
<journal-title><![CDATA[Neumología y cirugía de tórax]]></journal-title>
<abbrev-journal-title><![CDATA[Neumol. cir. torax]]></abbrev-journal-title>
<issn>0028-3746</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Mexicana de Neumología y Cirugía de Tórax; Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas; Sociedad Cubana de Neumología; Sociedad Paraguaya de Neumología; Sociedad Boliviana de Neumología.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0028-37462018000200157</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Tabaquismo y cáncer de pulmón. Cincuenta años de evidencia]]></article-title>
<article-title xml:lang="en"><![CDATA[Smoking and lung cancer. Fifty years of evidence]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Thirión-Romero]]></surname>
<given-names><![CDATA[Ireri]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Pérez-Padilla]]></surname>
<given-names><![CDATA[Rogelio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[García-Sancho]]></surname>
<given-names><![CDATA[Cecilia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Torre-Bouscoulet]]></surname>
<given-names><![CDATA[Luis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2018</year>
</pub-date>
<volume>77</volume>
<numero>2</numero>
<fpage>157</fpage>
<lpage>161</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0028-37462018000200157&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0028-37462018000200157&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0028-37462018000200157&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: A principios de la década de 1950 aparecieron las primeras evidencias epidemiológicas de la asociación entre tabaquismo y cáncer de pulmón. La relación causal se documentó hacia mediados de la década de 1960 y fue hasta principios de la década siguiente cuando se implementó la primera medida eficaz: el incremento del impuesto al tabaco. La investigación durante los últimos 50 años ha demostrado la relación causal entre tabaquismo con diferentes cánceres y enfermedades crónicas; no obstante, actualmente uno de cada cuatro hombres en el mundo fuma y la mayoría vive en países en desarrollo. El tabaquismo es una enfermedad que se comporta como una epidemia cuya persistencia es un reflejo de las fallas, durante décadas, para reconocerlo como un problema global y tomar medidas en materia de salud pública. Los esfuerzos integrados de gobiernos, sociedades científicas, organizaciones no gubernamentales y prestadores de servicios de salud deben ser más eficientes para hacer frente a la lacerante epidemia mundial del tabaquismo.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: In the early 1950&#8217;s appeared the first epidemiological evidence between the association of smoking and lung cancer. Causal relationship was documented around the middle of the 1960&#8217;s and it was not until the following decade that the first effective measure was implemented: tobacco tax increase. Over the last 50 years research has shown the causal relationship between smoking with different cancer and chronic diseases; however, one of four men in the world continue smoking and majority lives in developing countries. Tobacco is a disease that behaves like an epidemic whose persistence is a reflection of health failures, from decades, to recognize it as a global problem and take action on public health. Integral government&#8217;s, Scientific&#8217;s, nongovernmental organizations and health service provider&#8217;s efficient efforts must be done in dealing with the shattering global tobacco epidemic.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Tabaquismo]]></kwd>
<kwd lng="es"><![CDATA[cáncer pulmonar]]></kwd>
<kwd lng="es"><![CDATA[Convenio Marco]]></kwd>
<kwd lng="es"><![CDATA[MPOWER]]></kwd>
<kwd lng="en"><![CDATA[Tobacco]]></kwd>
<kwd lng="en"><![CDATA[lung cancer]]></kwd>
<kwd lng="en"><![CDATA[Marco Agreement]]></kwd>
<kwd lng="en"><![CDATA[MPOWER]]></kwd>
</kwd-group>
</article-meta>
</front><back>
<ref-list>
<ref id="B1">
<label>1</label><nlm-citation citation-type="journal">
<collab>GBD 2015 Tobacco Collaborators</collab>
<article-title xml:lang=""><![CDATA[Smoking prevalence and attributable disease burden in 195 countries and territories, 1990-2015: a systematic analysis from the Global Burden of Disease Study 2015]]></article-title>
<source><![CDATA[Lancet]]></source>
<year>2017</year>
<volume>389</volume>
<numero>10082</numero>
<issue>10082</issue>
<page-range>1885-906</page-range></nlm-citation>
</ref>
<ref id="B2">
<label>2</label><nlm-citation citation-type="journal">
<collab>GBD 2015 Risk Factors Collaborators</collab>
<article-title xml:lang=""><![CDATA[Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015]]></article-title>
<source><![CDATA[Lancet]]></source>
<year>2016</year>
<volume>388</volume>
<numero>10053</numero>
<issue>10053</issue>
<page-range>1659-724</page-range></nlm-citation>
</ref>
<ref id="B3">
<label>3</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Jha]]></surname>
<given-names><![CDATA[P]]></given-names>
</name>
<name>
<surname><![CDATA[Peto]]></surname>
<given-names><![CDATA[R]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Global effects of smoking, of quitting, and of taxing tobacco]]></article-title>
<source><![CDATA[N Engl J Med]]></source>
<year>2014</year>
<volume>370</volume>
<numero>1</numero>
<issue>1</issue>
<page-range>60-8</page-range></nlm-citation>
</ref>
<ref id="B4">
<label>4</label><nlm-citation citation-type="book">
<collab>National Center for Chronic Disease Prevention and Health Promotion (US) Office on Smoking and Health</collab>
<source><![CDATA[The Health Consequences of Smoking-50 Years of Progress: A Report of the Surgeon General]]></source>
<year>2014</year>
<publisher-loc><![CDATA[Atlanta (GA) ]]></publisher-loc>
<publisher-name><![CDATA[Centers for Disease Control and Prevention (US)]]></publisher-name>
</nlm-citation>
</ref>
<ref id="B5">
<label>5</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Doll]]></surname>
<given-names><![CDATA[R]]></given-names>
</name>
<name>
<surname><![CDATA[Peto]]></surname>
<given-names><![CDATA[R]]></given-names>
</name>
<name>
<surname><![CDATA[Boreham]]></surname>
<given-names><![CDATA[J]]></given-names>
</name>
<name>
<surname><![CDATA[Sutherland]]></surname>
<given-names><![CDATA[I]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Mortality in relation to smoking: 50 years&#8217; observations on male British doctors]]></article-title>
<source><![CDATA[BMJ]]></source>
<year>2004</year>
<volume>328</volume>
<numero>7455</numero>
<issue>7455</issue>
<page-range>1519</page-range></nlm-citation>
</ref>
<ref id="B6">
<label>6</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Guerrero-López]]></surname>
<given-names><![CDATA[CM]]></given-names>
</name>
<name>
<surname><![CDATA[Muños-Hernández]]></surname>
<given-names><![CDATA[JA]]></given-names>
</name>
<name>
<surname><![CDATA[Sáenz de Miera-Juárez]]></surname>
<given-names><![CDATA[B]]></given-names>
</name>
<name>
<surname><![CDATA[Luz Reynales-Shigematsu]]></surname>
<given-names><![CDATA[LM]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Consumo de tabaco, mortalidad y política fiscal en México]]></article-title>
<source><![CDATA[Salud Publica Mex]]></source>
<year>2013</year>
<volume>55</volume>
<numero>^s2</numero>
<issue>^s2</issue>
<supplement>2</supplement>
<page-range>S276-81</page-range></nlm-citation>
</ref>
<ref id="B7">
<label>7</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Doll]]></surname>
<given-names><![CDATA[R]]></given-names>
</name>
<name>
<surname><![CDATA[Hill]]></surname>
<given-names><![CDATA[AB]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Smoking and carcinoma of the lung; preliminary report]]></article-title>
<source><![CDATA[Br Med J]]></source>
<year>1950</year>
<volume>2</volume>
<numero>4682</numero>
<issue>4682</issue>
<page-range>739-48</page-range></nlm-citation>
</ref>
<ref id="B8">
<label>8</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Parascandola]]></surname>
<given-names><![CDATA[J]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[The surgeons general and smoking]]></article-title>
<source><![CDATA[Public Health Rep]]></source>
<year>1997</year>
<volume>112</volume>
<numero>5</numero>
<issue>5</issue>
<page-range>440-2</page-range></nlm-citation>
</ref>
<ref id="B9">
<label>9</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Doll]]></surname>
<given-names><![CDATA[R]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Tobacco: a medical history]]></article-title>
<source><![CDATA[J Urban Health]]></source>
<year>1999</year>
<volume>76</volume>
<numero>3</numero>
<issue>3</issue>
<page-range>289-313</page-range></nlm-citation>
</ref>
<ref id="B10">
<label>10</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Terry]]></surname>
<given-names><![CDATA[L]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[The health officer and medical care administration]]></article-title>
<source><![CDATA[Am J Public Health Nations Health]]></source>
<year>1964</year>
<volume>54</volume>
<page-range>1799-803</page-range></nlm-citation>
</ref>
<ref id="B11">
<label>11</label><nlm-citation citation-type="">
<collab>U.S Department of Health, Education, and Welfare. Public Health Service. Smoking and Health</collab>
<source><![CDATA[Report of the advisory committee to the Surgeon General of the Public Health Service]]></source>
<year>1964</year>
<publisher-loc><![CDATA[Washington, D.C ]]></publisher-loc>
</nlm-citation>
</ref>
<ref id="B12">
<label>12</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Doll]]></surname>
<given-names><![CDATA[R]]></given-names>
</name>
<name>
<surname><![CDATA[Hill]]></surname>
<given-names><![CDATA[AB]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[The mortality of doctors in relation to their smoking habits; a preliminary report]]></article-title>
<source><![CDATA[Br Med J]]></source>
<year>1954</year>
<volume>1</volume>
<numero>4877</numero>
<issue>4877</issue>
<page-range>1451-5</page-range></nlm-citation>
</ref>
<ref id="B13">
<label>13</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Richmond]]></surname>
<given-names><![CDATA[C]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[In Memoriam. Sir Richard Doll, epidemiólogo que demostró que el tabaco causa cáncer y enfermedades de corazón]]></article-title>
<source><![CDATA[Salud Publica Mex]]></source>
<year>2005</year>
<volume>47</volume>
<numero>4</numero>
<issue>4</issue>
<page-range>319-22</page-range></nlm-citation>
</ref>
<ref id="B14">
<label>14</label><nlm-citation citation-type="">
<source><![CDATA[How the cancer prevention studies save lives]]></source>
<year>2018</year>
</nlm-citation>
</ref>
<ref id="B15">
<label>15</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Samet]]></surname>
<given-names><![CDATA[JM]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[The Surgeon Generals&#8217; reports and respiratory diseases. From 1964 to 2014]]></article-title>
<source><![CDATA[Ann Am Thorac Soc]]></source>
<year>2014</year>
<volume>11</volume>
<numero>2</numero>
<issue>2</issue>
<page-range>141-8</page-range></nlm-citation>
</ref>
<ref id="B16">
<label>16</label><nlm-citation citation-type="">
<collab>Disease Control Center for Chronic Disease Prevention Promotion on Smoking. Department of Health Services for Disease Control, Center for Chronic Disease Prevention, Promotion on Smoking</collab>
<source><![CDATA[E-cigarette use among youth and young adults: a report of the surgeon general]]></source>
<year>2016</year>
</nlm-citation>
</ref>
<ref id="B17">
<label>17</label><nlm-citation citation-type="">
<collab>American Lung Association</collab>
<source><![CDATA[10 of the worst diseases smoking cause]]></source>
<year>2016</year>
</nlm-citation>
</ref>
<ref id="B18">
<label>18</label><nlm-citation citation-type="">
<collab>WHO</collab>
<source><![CDATA[El Convenio Marco de la OMS para el Control del Tabaco]]></source>
<year>2018</year>
</nlm-citation>
</ref>
<ref id="B19">
<label>19</label><nlm-citation citation-type="">
<collab>Organización Mundial de la Salud</collab>
<source><![CDATA[Convenio Marco de la OMS para el control del tabaco]]></source>
<year>2003</year>
</nlm-citation>
</ref>
<ref id="B20">
<label>20</label><nlm-citation citation-type="">
<collab>Secretaría de Salud</collab>
<source><![CDATA[Ley General para el Control del Tabaco y su Reglamento]]></source>
<year>2009</year>
</nlm-citation>
</ref>
<ref id="B21">
<label>21</label><nlm-citation citation-type="book">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Mamudu]]></surname>
<given-names><![CDATA[HM]]></given-names>
</name>
</person-group>
<collab>Naciones Unidas</collab>
<source><![CDATA[Declaración Política de la Reunión de Alto Nivel de la Asamblea General sobre la Prevención y el Control de las Enfermedades No Transmisibles. Septiembre de 2011]]></source>
<year>2011</year>
<publisher-name><![CDATA[UN resolution on the prevention]]></publisher-name>
</nlm-citation>
</ref>
<ref id="B22">
<label>22</label><nlm-citation citation-type="book">
<collab>Organización Mundial de la Salud. MPOWER</collab>
<source><![CDATA[Un plan de medidas para hacer retroceder la epidemia de tabaquismo]]></source>
<year>2008</year>
<publisher-name><![CDATA[Organización Mundial de la Salud]]></publisher-name>
</nlm-citation>
</ref>
<ref id="B23">
<label>23</label><nlm-citation citation-type="">
<collab>Center for Disease Control and Prevention MMWR</collab>
<source><![CDATA[Current Cigarette Smoking Among Adults-United States, 2005-2014]]></source>
<year>2015</year>
</nlm-citation>
</ref>
<ref id="B24">
<label>24</label><nlm-citation citation-type="">
<collab>Instituto Nacional de Salud Pública</collab>
<source><![CDATA[Encuesta Nacional de Salud y Nutrición, Resultados Nacionales]]></source>
<year>2012</year>
</nlm-citation>
</ref>
<ref id="B25">
<label>25</label><nlm-citation citation-type="">
<collab>Gobierno Federal</collab>
<source><![CDATA[Encuesta Nacional de Adicciones 2011 Drogas Ilícitas]]></source>
<year>2011</year>
</nlm-citation>
</ref>
<ref id="B26">
<label>26</label><nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Monraz-Pérez]]></surname>
<given-names><![CDATA[S]]></given-names>
</name>
<name>
<surname><![CDATA[Regalado-Pineda]]></surname>
<given-names><![CDATA[J]]></given-names>
</name>
<name>
<surname><![CDATA[Pérez-Padilla]]></surname>
<given-names><![CDATA[R]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[El cigarro electrónico: Peligro u oportunidad]]></article-title>
<source><![CDATA[Neumol Cir Torax]]></source>
<year>2015</year>
<volume>74</volume>
<numero>2</numero>
<issue>2</issue>
<page-range>82-6</page-range></nlm-citation>
</ref>
<ref id="B27">
<label>27</label><nlm-citation citation-type="">
<collab>WHO</collab>
<source><![CDATA[Día Mundial sin Tabaco 2017]]></source>
<year>2017</year>
</nlm-citation>
</ref>
<ref id="B28">
<label>28</label><nlm-citation citation-type="">
<collab>World Health Organization</collab>
<source><![CDATA[WHO Report on the Global Tobacco Epidemic, 2017]]></source>
<year>2017</year>
</nlm-citation>
</ref>
<ref id="B29">
<label>29</label><nlm-citation citation-type="">
<collab>Chest, American College of Chest Physicians</collab>
<source><![CDATA[World Lung Cancer Day]]></source>
<year>2018</year>
</nlm-citation>
</ref>
<ref id="B30">
<label>30</label><nlm-citation citation-type="">
<collab>Forum of International Respiratory Societies, United for Lung Health</collab>
<source><![CDATA[Lung Cancer Fact Sheet]]></source>
<year>2017</year>
</nlm-citation>
</ref>
</ref-list>
</back>
</article>
