<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2954-3835</journal-id>
<journal-title><![CDATA[Cardiovascular and metabolic science]]></journal-title>
<abbrev-journal-title><![CDATA[Cardiovasc. metab. sci]]></abbrev-journal-title>
<issn>2954-3835</issn>
<publisher>
<publisher-name><![CDATA[Asociación Nacional de Cardiólogos de México A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2954-38352023000100021</article-id>
<article-id pub-id-type="doi">10.35366/110249</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Clinical application rules]]></article-title>
<article-title xml:lang="es"><![CDATA[Reglas de aplicación clínica]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Moragrega-Adame]]></surname>
<given-names><![CDATA[José Luis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,FACC  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>USA</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2023</year>
</pub-date>
<volume>34</volume>
<numero>1</numero>
<fpage>21</fpage>
<lpage>24</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S2954-38352023000100021&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S2954-38352023000100021&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S2954-38352023000100021&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: Decision-making in the daily practice of medicine requires amalgamating the experience of the physician, the data derived from scientific studies as well as the available resources and preferences of patients. Evidence-based medicine helps in these tasks and clinical guidelines have served as support, but the doctor must reinforce his knowledge of epidemiology, statistics and scientific method to be better prepared when deciding which data can be incorporated into the practice of medicine, which should be discarded and identify those that require confirmation. This article presents the most important elements to consider when deciding on the applicability of data from research studies and clinical epidemiology.]]></p></abstract>
<abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: La toma de decisiones en la práctica diaria de la medicina requiere amalgamar la experiencia del médico, los datos derivados de estudios científicos, así como los recursos disponibles y las preferencias de los pacientes. La medicina basada en evidencias ayuda en estas tareas y las guías clínicas han servido de apoyo, pero el médico debe reforzar sus conocimientos de epidemiología, estadística y método científico para estar mejor preparado a la hora de decidir qué datos se pueden incorporar a la práctica de la medicina, cuáles deben descartarse e identificar aquellos que requieren confirmación. Este artículo presenta los elementos más importantes a considerar al decidir sobre la aplicabilidad de los datos de los estudios de investigación y la epidemiología clínica.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[epidemiology]]></kwd>
<kwd lng="en"><![CDATA[clinical]]></kwd>
<kwd lng="en"><![CDATA[application]]></kwd>
<kwd lng="es"><![CDATA[epidemiología]]></kwd>
<kwd lng="es"><![CDATA[clínica]]></kwd>
<kwd lng="es"><![CDATA[aplicación]]></kwd>
</kwd-group>
</article-meta>
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