<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0186-4866</journal-id>
<journal-title><![CDATA[Medicina interna de México]]></journal-title>
<abbrev-journal-title><![CDATA[Med. interna Méx.]]></abbrev-journal-title>
<issn>0186-4866</issn>
<publisher>
<publisher-name><![CDATA[Edición y Farmacia S.A. de C.V.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0186-48662018000400006</article-id>
<article-id pub-id-type="doi">10.24245/mim.v34i4.1828</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Asociación entre la severidad de la depresión y el apego al primer esquema de tratamiento antirretroviral]]></article-title>
<article-title xml:lang="en"><![CDATA[Association of depression severity with adherence to the first scheme of antiretroviral treatment.]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[López-Hernández]]></surname>
<given-names><![CDATA[Marco Antonio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Montoya-Escutia]]></surname>
<given-names><![CDATA[Patricia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,IMSS  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>08</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>08</month>
<year>2018</year>
</pub-date>
<volume>34</volume>
<numero>4</numero>
<fpage>557</fpage>
<lpage>560</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0186-48662018000400006&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0186-48662018000400006&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0186-48662018000400006&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  OBJETIVO Comparar el índice de apego a la terapia antirretroviral de primera línea en pacientes con trastornos depresivos vs pacientes sin depresión.  MATERIAL Y MÉTODO  Estudio prospectivo efectuado de enero a junio de 2016 en el que se evaluaron pacientes de las clínicas de VIH del Hospital General Regional núm. 1 del IMSS y del Hospital General Tacuba, en tratamiento antirretroviral con un primer esquema, iniciado hacía más de seis meses; se excluyeron los pacientes con trastornos neurológicos diferentes a depresión, pacientes con diagnóstico, tratamiento previo de depresión o ambos. Los pacientes respondieron el cuestionario de Beck de depresión y la escala SMAQ de apego.  RESULTADOS Se evaluaron 180 pacientes con un primer esquema de tratamiento antirretroviral, se encontró que 126 (70%) pacientes no tenían depresión, 36 (20%) tenían depresión, 15 (8.3%) depresión moderada y 3 (1.7%) depresión severa. La falta de apego se observó en 15.8% de los pacientes sin depresión versus 55.5% de los pacientes con depresión (p = 0.01). El apego de los pacientes con depresión fue inversamente proporcional a la severidad de la misma. Respecto a la carga viral bajo el límite de supresión (&lt; 40 copias/mL) en los pacientes sin depresión se observó mayor proporción de pacientes con carga viral superior a 40 copias/mL: 17.4 vs 15.87%, considerados sin apego por el cuestionario SMAQ.  CONCLUSIONES El apego disminuye con la severidad de la depresión en los pacientes, lo que pone en riesgo la eficacia del tratamiento antirretroviral.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  OBJECTIVE To compare the rate of adherence to antiretroviral therapy in the first line in patients with depressive disorders vs those without depression.  MATERIAL AND METHOD  A prospective study was done from January to June 2016 in patients from the HIV clinics of the Regional General Hospital No. 1 of IMSS, and the General Hospital Tacuba, in antiretroviral treatment with a first scheme, started more than six months ago, excluding patients with neurological disorders, different from depression, patients with diagnosis and/or previous treatment of depression. Patients answered the Beck questionnaire for depression and the SMAQ scale for adherence.  RESULTS 180 patients were evaluated with a first antiretroviral treatment regimen. It was found that 126 (70%) patients did not present depression, 36 (20%) presented depression, 15 (8.3%) presented moderate depression and 3 (1.7%) presented severe depression. Non-adherence was observed in 15.8% of patients without depression versus 55.5% of patients with depression (p = 0.01). The adherence of patients with depression was inversely proportional to the severity of the same. Regarding the viral load under the limit of suppression (&lt; 40 copies/mL) in patients without depression, a higher proportion of patients with a viral load higher than 40 copies/mL was observed: 17.4% vs 15.8%, considered non-adherent by the SMAQ questionnaire.  CONCLUSIONS Adherence decreases with the severity of depression in patients, putting the effectiveness of antiretroviral treatment at risk.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Terapia antirretroviral]]></kwd>
<kwd lng="es"><![CDATA[depresión]]></kwd>
<kwd lng="es"><![CDATA[VIH]]></kwd>
<kwd lng="en"><![CDATA[Antiretroviral therapy]]></kwd>
<kwd lng="en"><![CDATA[Depression]]></kwd>
<kwd lng="en"><![CDATA[HIV]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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