<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0186-4866</journal-id>
<journal-title><![CDATA[Medicina interna de México]]></journal-title>
<abbrev-journal-title><![CDATA[Med. interna Méx.]]></abbrev-journal-title>
<issn>0186-4866</issn>
<publisher>
<publisher-name><![CDATA[Edición y Farmacia S.A. de C.V.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0186-48662017000200151</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Lesión renal aguda en pacientes sometidos a apendicectomía]]></article-title>
<article-title xml:lang="en"><![CDATA[Acute renal lesion in patients submitted to apendicectomy]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Vicente-Hernández]]></surname>
<given-names><![CDATA[B]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Pérez-Beltrán]]></surname>
<given-names><![CDATA[CF]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez-Weber]]></surname>
<given-names><![CDATA[F]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Díaz-Greene]]></surname>
<given-names><![CDATA[EJ]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad La Salle Facultad Mexicana de Medicina ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad La Salle Facultad Mexicana de Medicina ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad La Salle Facultad Mexicana de Medicina ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>04</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>04</month>
<year>2017</year>
</pub-date>
<volume>33</volume>
<numero>2</numero>
<fpage>151</fpage>
<lpage>158</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0186-48662017000200151&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0186-48662017000200151&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0186-48662017000200151&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  ANTECEDENTES: la lesión renal aguda es una disfunción aguda multifactorial. En el periodo posquirúrgico aumenta la mortalidad y morbilidad y existe poca información acerca de lesión renal aguda en cirugías no cardiacas. El gasto urinario es un índice funcional y biomarcador de lesión tubular, aparte de los criterios diagnósticos.  OBJETIVO: determinar la incidencia de lesión renal aguda en pacientes posapendicectomía, la existencia de oliguria posquirúrgica y los factores de riesgo de lesión renal aguda.  MATERIAL Y MÉTODO: estudio observacional, transversal, retrospectivo, en el que revisamos los expedientes de pacientes sometidos a apendicectomía de febrero de 2015 a enero de 2016 en el Hospital Ángeles Pedregal. Incluimos pacientes mayores de 18 años y excluimos a los pacientes sin control de líquidos. Se definió y clasificó la lesión renal aguda con las guías KDIGO. Los datos demográficos se expresan en medianas. Utilizamos &#967;2 de Pearson como medida no paramétrica y presentamos datos en razón de momios (OR) con intervalo de confianza (IC) de 95%.  RESULTADOS: en 12 meses se revisaron 196 expedientes; 114 pacientes no cumplieron con control de líquidos y se excluyeron, quedaron 82 pacientes para análisis. Encontramos incidencia de 26% de lesión renal aguda, 48% en estadio 1 y 52% en estadio 2. El 62% eran mujeres. La mediana de edad en el grupo de lesión renal aguda fue de 38 años (límites: 18-77). Del grupo sin lesión renal aguda, 54% tuvo oliguria transitoria en recuperación y 21% oliguria transitoria a las cuatro horas. En el grupo de lesión renal aguda, 76% tenía oliguria en recuperación (p=0.097, OR 2.54 IC 95% 0.826-7.820). El 81% tenía oliguria cuatro horas después de la cirugía (p&#8804;0.05, OR 13.66 IC 95% 3.94-47.6), la sensibilidad y especificidad fueron de 80 y 79%, respectivamente; el valor predictivo positivo fue de 56% y el valor predictivo negativo de 92%.  CONCLUSIONES: encontramos incidencia similar a la reportada en estudios previos; sin embargo, tuvimos más casos de estadio 2. Encontramos una asociación estadísticamente significativa entre diuresis media horaria a las cuatro horas y lesión renal aguda. La lesión renal aguda en el periodo posquirúrgico se ha relacionado con mal pronós tico, por lo que su detección oportuna para el manejo adecuado es importante. La existencia de lesión renal aguda en nuestra población es considerable y el control estricto de líquidos es indispensable para la detección oportuna, la medición de la diuresis media horaria cuatro horas después de la cirugía puede alertar sobre qué pacientes pueden padecer lesión renal aguda a las 6 y 12 horas, para iniciar la intervención y abordaje oportunos.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  BACKGROUND: Acute kidney injury (AKI) is a multifactorial acute dysfunction. In the postoperative period is associated with more morbidity and mortality and we have little information on AKI in noncardiac surgeries. Urine output (UO) is a functional index and a biomarker of tubular injury.  OBJECTIVE: To determine the incidence of AKI in patients post-appendectomy, the presence of postoperative oliguria and risk factors.  MATERIAL AND METHOD: An observational, transversal, retrospective study was done. We reviewed records of patients undergoing appendectomy from February 2015 to January 2016 in the Hospital Ángeles Pedregal, Mexico City. We included patients aged 18 years and excluded patients without control of liquids. AKI was defined and classified by KDIGO guidelines. Demographics were expressed in medians. We used &#967;2 Pearson as parametric measure and present data in OR with confidence interval (CI) 95%.  RESULTS: In 12 months, 196 cases were reviewed. 114 patients did not meet fluid control and were excluded, left 82 patients for analysis. We found an AKI incidence of 26%, AKI I, 48% and AKI II, 52%. The median age in the AKI group was 38 years (18-77). From no-AKI group, 54% showed transient oliguria recovering transient oliguria and 21% at 4 hours. In the AKI group, 76% had oliguria in recovery (p=0.097, OR 2.54 95% CI 0.826-7.820); 81% had oliguria at 4 hours after surgery (p&#8804;0.05, OR 95% CI 3.94-47.6 13.66), sensitivity and specificity of 80% and 79%, PPV 56% and NPV 92%.  CONCLUSION: We found a similar incidence reported in previous studies; however, we have more AKI II cases. We found a statistically significant association between UO 4 hours and AKI. AKI in the postoperative period has been associated with poor prognosis, so that timely detection for the proper handling is important. The presence of AKI in our population is considerable and strict control of fluids is essential for early detection, UO 4 hours after surgery can alert that patients may have AKI at 6 and 12 hours, starting an intervention.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[lesión renal aguda]]></kwd>
<kwd lng="es"><![CDATA[posquirúrgico]]></kwd>
<kwd lng="es"><![CDATA[apendicectomía]]></kwd>
<kwd lng="en"><![CDATA[acute kidney injury]]></kwd>
<kwd lng="en"><![CDATA[post-surgery]]></kwd>
<kwd lng="en"><![CDATA[appendectomy]]></kwd>
</kwd-group>
</article-meta>
</front><back>
<ref-list>
<ref id="B1">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[Kidney Disease: Improving Global Outcome (KDIGO) Acute Kidney Injury Work Group. KDIGO Clinical Practice Guideline for Acute Kidney Injury]]></article-title>
<source><![CDATA[Kidney Int]]></source>
<year>2012</year>
<numero>^s2</numero>
<issue>^s2</issue>
<supplement>2</supplement>
<page-range>1-138</page-range></nlm-citation>
</ref>
<ref id="B2">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[Peri-operative renal dysfunction prevention and management]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Golden]]></surname>
<given-names><![CDATA[D]]></given-names>
</name>
<name>
<surname><![CDATA[Corbett]]></surname>
<given-names><![CDATA[J]]></given-names>
</name>
<name>
<surname><![CDATA[Forni]]></surname>
<given-names><![CDATA[G]]></given-names>
</name>
</person-group>
<source><![CDATA[Anaesthesia]]></source>
<year>2016</year>
<volume>71</volume>
<page-range>51-7</page-range></nlm-citation>
</ref>
<ref id="B3">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[Acute kidney injury A clinical syndrome]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Bienholz]]></surname>
<given-names><![CDATA[A]]></given-names>
</name>
<name>
<surname><![CDATA[Kribben]]></surname>
<given-names><![CDATA[A]]></given-names>
</name>
</person-group>
<source><![CDATA[Internist (Berl)]]></source>
<year>2016</year>
</nlm-citation>
</ref>
<ref id="B4">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[Acute kidney injury after major abdominal surgery: A retrospective cohort analysis]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Teixeira]]></surname>
<given-names><![CDATA[C]]></given-names>
</name>
<name>
<surname><![CDATA[Rosario]]></surname>
<given-names><![CDATA[R]]></given-names>
</name>
<name>
<surname><![CDATA[Rodrigues]]></surname>
<given-names><![CDATA[N]]></given-names>
</name>
</person-group>
<source><![CDATA[Crit Care Res Pract]]></source>
<year>2014</year>
</nlm-citation>
</ref>
<ref id="B5">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[Post-operative acute kidney injury in high-risk patients undergoing major abdominal surgery]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Romagnoli]]></surname>
<given-names><![CDATA[S]]></given-names>
</name>
<name>
<surname><![CDATA[Zagli]]></surname>
<given-names><![CDATA[G]]></given-names>
</name>
<name>
<surname><![CDATA[Ticariardi]]></surname>
<given-names><![CDATA[G]]></given-names>
</name>
</person-group>
<source><![CDATA[J Crit Care]]></source>
<year>2016</year>
<volume>35</volume>
<page-range>120-5</page-range></nlm-citation>
</ref>
<ref id="B6">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[Variations in the risk of acute kidney injury across intraabdominal surgery procedures]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Kim]]></surname>
<given-names><![CDATA[M]]></given-names>
</name>
<name>
<surname><![CDATA[Brady]]></surname>
<given-names><![CDATA[J]]></given-names>
</name>
<name>
<surname><![CDATA[Li]]></surname>
<given-names><![CDATA[G]]></given-names>
</name>
</person-group>
<source><![CDATA[Anesth Analg]]></source>
<year>2014</year>
<volume>119</volume>
<page-range>1121-32</page-range></nlm-citation>
</ref>
<ref id="B7">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[Infra-abdominal pressure as a predictor of acute kidney injury in postoperative abdominal surgery]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Demarchi]]></surname>
<given-names><![CDATA[A]]></given-names>
</name>
<name>
<surname><![CDATA[De Almeida]]></surname>
<given-names><![CDATA[C]]></given-names>
</name>
<name>
<surname><![CDATA[Ponce]]></surname>
<given-names><![CDATA[D]]></given-names>
</name>
</person-group>
<source><![CDATA[Ren Fail]]></source>
<year>2014</year>
<volume>36</volume>
<page-range>557-61</page-range></nlm-citation>
</ref>
<ref id="B8">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[The definition and detection of acute kidney injury]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Pickering]]></surname>
<given-names><![CDATA[J]]></given-names>
</name>
<name>
<surname><![CDATA[Endre]]></surname>
<given-names><![CDATA[Z]]></given-names>
</name>
</person-group>
<source><![CDATA[J Renal Inj Prev]]></source>
<year>2014</year>
<volume>3</volume>
<page-range>21-5</page-range></nlm-citation>
</ref>
<ref id="B9">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[The influence of propofol and sevoflurane on acute kidney injury after colorectal surgery A retrospective cohort study]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Bang]]></surname>
<given-names><![CDATA[J]]></given-names>
</name>
<name>
<surname><![CDATA[Lee]]></surname>
<given-names><![CDATA[J]]></given-names>
</name>
<name>
<surname><![CDATA[Oh]]></surname>
<given-names><![CDATA[J]]></given-names>
</name>
</person-group>
<source><![CDATA[Anesth Analg]]></source>
<year>2016</year>
<volume>123</volume>
<page-range>363-70</page-range></nlm-citation>
</ref>
<ref id="B10">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[Acute kidney injury]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Anathhanam]]></surname>
<given-names><![CDATA[S]]></given-names>
</name>
<name>
<surname><![CDATA[Lewington]]></surname>
<given-names><![CDATA[A]]></given-names>
</name>
</person-group>
<source><![CDATA[J R Coll Physicians Edinb]]></source>
<year>2013</year>
<volume>43</volume>
<page-range>323-8</page-range></nlm-citation>
</ref>
<ref id="B11">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[Preoperative statin use and postoperative acute kidney injury]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Brunelli]]></surname>
<given-names><![CDATA[S]]></given-names>
</name>
<name>
<surname><![CDATA[Waikar]]></surname>
<given-names><![CDATA[S]]></given-names>
</name>
<name>
<surname><![CDATA[Bateman]]></surname>
<given-names><![CDATA[B]]></given-names>
</name>
</person-group>
<source><![CDATA[Am J Med]]></source>
<year>2012</year>
<volume>125</volume>
<page-range>1195-204</page-range></nlm-citation>
</ref>
<ref id="B12">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[Epidemiology of postoperative acute kidney injury in Hungarian intensive care units an exploratory analysis]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Medve]]></surname>
<given-names><![CDATA[L]]></given-names>
</name>
<name>
<surname><![CDATA[Gondos]]></surname>
<given-names><![CDATA[T]]></given-names>
</name>
</person-group>
<source><![CDATA[Ren Fail]]></source>
<year>2012</year>
<volume>34</volume>
<page-range>1074-8</page-range></nlm-citation>
</ref>
<ref id="B13">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[Acute kidney injury after abdominal surgery Incidence, risk factors, and outcome]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Long]]></surname>
<given-names><![CDATA[T]]></given-names>
</name>
<name>
<surname><![CDATA[Helgason]]></surname>
<given-names><![CDATA[D]]></given-names>
</name>
<name>
<surname><![CDATA[Helgadottir]]></surname>
<given-names><![CDATA[S]]></given-names>
</name>
</person-group>
<source><![CDATA[Anesth Analg]]></source>
<year>2016</year>
<volume>122</volume>
<page-range>1912-20</page-range></nlm-citation>
</ref>
<ref id="B14">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[Fluid electrolyte overload in critically ill patients An overview]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Besen]]></surname>
<given-names><![CDATA[MB]]></given-names>
</name>
<name>
<surname><![CDATA[Nunes]]></surname>
<given-names><![CDATA[A]]></given-names>
</name>
<name>
<surname><![CDATA[García]]></surname>
<given-names><![CDATA[L]]></given-names>
</name>
</person-group>
<source><![CDATA[World J Crit Care Med]]></source>
<year>2015</year>
<volume>4</volume>
<page-range>116-29</page-range></nlm-citation>
</ref>
<ref id="B15">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[&#8220;Quadruple whammy&#8221; A presentable newly described syndrome of post-operative AKI in CKD II and CKD III patients on combination &#8220;Triple whammy&#8221; medications: A Mayo Clinic Health System, Eau Claire, Wisconsin experience]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Onuigbo]]></surname>
<given-names><![CDATA[M]]></given-names>
</name>
<name>
<surname><![CDATA[Agbasi]]></surname>
<given-names><![CDATA[N]]></given-names>
</name>
</person-group>
<source><![CDATA[Nigerian J Clin Pract]]></source>
<year>2014</year>
<volume>17</volume>
<page-range>649-54</page-range></nlm-citation>
</ref>
<ref id="B16">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[Oliguria and biomarkers of acute kidney injury Star struck lovers or strangers in the night?]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Lehner]]></surname>
<given-names><![CDATA[G]]></given-names>
</name>
<name>
<surname><![CDATA[Forni]]></surname>
<given-names><![CDATA[L]]></given-names>
</name>
<name>
<surname><![CDATA[Joannidis]]></surname>
<given-names><![CDATA[M]]></given-names>
</name>
</person-group>
<source><![CDATA[Nephron]]></source>
<year>2016</year>
</nlm-citation>
</ref>
<ref id="B17">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[Etiology and outcomes of anuria in acute kidney injury a single center study]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Choi]]></surname>
<given-names><![CDATA[HM]]></given-names>
</name>
<name>
<surname><![CDATA[Kim]]></surname>
<given-names><![CDATA[SC]]></given-names>
</name>
<name>
<surname><![CDATA[Kim]]></surname>
<given-names><![CDATA[MG]]></given-names>
</name>
</person-group>
<source><![CDATA[Kidney Res Clin Pract]]></source>
<year>2015</year>
<volume>34</volume>
<page-range>13-9</page-range></nlm-citation>
</ref>
<ref id="B18">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[Serum cystatin C is a sensitive early marker for changes in the glomerular filtration rate in patients undergoing laparoscopic surgery]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Moreira]]></surname>
<given-names><![CDATA[RH]]></given-names>
</name>
<name>
<surname><![CDATA[Camacho]]></surname>
<given-names><![CDATA[L]]></given-names>
</name>
<name>
<surname><![CDATA[Nakamura]]></surname>
<given-names><![CDATA[G]]></given-names>
</name>
</person-group>
<source><![CDATA[Clinics]]></source>
<year>2014</year>
<volume>69</volume>
<page-range>378-83</page-range></nlm-citation>
</ref>
<ref id="B19">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[Perioperative acute kidney injury]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Goren]]></surname>
<given-names><![CDATA[O]]></given-names>
</name>
<name>
<surname><![CDATA[Matot]]></surname>
<given-names><![CDATA[I]]></given-names>
</name>
</person-group>
<source><![CDATA[Br J Anaesth]]></source>
<year>2015</year>
<volume>115</volume>
<page-range>ii3-ii14</page-range></nlm-citation>
</ref>
<ref id="B20">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[Acute kidney injury in the perioperative period and in intensive care units (excluding renal replacement therapies)]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Ichai]]></surname>
<given-names><![CDATA[C]]></given-names>
</name>
<name>
<surname><![CDATA[Vinsonneau]]></surname>
<given-names><![CDATA[C]]></given-names>
</name>
<name>
<surname><![CDATA[Souweine]]></surname>
<given-names><![CDATA[B]]></given-names>
</name>
</person-group>
<source><![CDATA[Ann Intensive Care]]></source>
<year>2016</year>
<volume>6</volume>
<page-range>48</page-range></nlm-citation>
</ref>
<ref id="B21">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[The risk of chronic kidney disease and mortality are increased after community-acquired acute kidney injury]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Soto]]></surname>
<given-names><![CDATA[K]]></given-names>
</name>
<name>
<surname><![CDATA[Campos]]></surname>
<given-names><![CDATA[P]]></given-names>
</name>
<name>
<surname><![CDATA[Pinto]]></surname>
<given-names><![CDATA[I]]></given-names>
</name>
</person-group>
<source><![CDATA[Kidney Int]]></source>
<year>2016</year>
<numero>16</numero>
<issue>16</issue>
<page-range>S0085- 2538</page-range></nlm-citation>
</ref>
<ref id="B22">
<nlm-citation citation-type="journal">
<article-title xml:lang=""><![CDATA[Acute kidney injury, long-term renal function and mortality in patients undergoing major abdominal surgery: a cohort analysis]]></article-title>
<person-group person-group-type="author">
<name>
<surname><![CDATA[Gameiro]]></surname>
<given-names><![CDATA[J]]></given-names>
</name>
<name>
<surname><![CDATA[Briosa]]></surname>
<given-names><![CDATA[J]]></given-names>
</name>
<name>
<surname><![CDATA[Rodrigues]]></surname>
<given-names><![CDATA[N]]></given-names>
</name>
</person-group>
<source><![CDATA[Clin Kidney J]]></source>
<year>2016</year>
<volume>9</volume>
<page-range>192-200</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
