2954-4122 2954-4122 S2954-41222022000100029 10.31157/an.vi.301 México El Salvador 00 03 2022 00 03 2022 27 1 29 38

1 1898 43 1 1 187-200 2 1898 10 4 4 113-7 3 1947 128 3 3 234-55 4 1953 31 3-4 3-4 68-9 5 1963 238 3148-50 6 1967 276 21 21 1163-7 7 2015 231-48 8 9 2012 259 6 6 1019-28 9 2018 3 11 2001 136 136 174-92 12 2006 79 1 1 31-40 13 2007 146 6 6 425-33 14 2005 366 9499 9499 1794-6 15 1996 6 2 2 75-9 16 2018 27 3 3 575-82 17 2017 48 7 7 1766-72 18 2010 5 1 1 30 19 2008 2 20 2001 8 3733-74 21 2002 13 S2 S2 S139-43 22 Genzyme, a Sanofi Company 2020 23 2015 46 1 1 302-13 24 2009 40 3 3 788-94 25 1996 40 1 1 8-17 26 1997 8 4 4 252-7 27 2011 18 2 2 347-53 28 1997 36 5 5 327-9 29 1998 8 4 4 265-7 30 2021 2nd 31 2001 308 1 1 195-6 32 2012 8 91-9 33 2004 114 4 4 909-16 34 2012 379 9813 9813 335-41 35 36 2020 108 2 2 326-37 37 2020 360 6 6 641-9 38 2015 22 2 2 423-5 39 2010 103 9 9 641-59 38 2020 360 6 6 641-9