<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2565-005X</journal-id>
<journal-title><![CDATA[Gaceta mexicana de oncología]]></journal-title>
<abbrev-journal-title><![CDATA[Gac. mex. oncol.]]></abbrev-journal-title>
<issn>2565-005X</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Mexicana de Oncología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2565-005X2020000500006</article-id>
<article-id pub-id-type="doi">10.24875/j.gamo.20000019</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Apendicitis aguda secundaria a melanoma]]></article-title>
<article-title xml:lang="en"><![CDATA[Acute appendicitis secondary to melanoma]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Desentis-Suárez]]></surname>
<given-names><![CDATA[Nicolás]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Avecilla-Guerrero]]></surname>
<given-names><![CDATA[Carlos A.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ramírez-Ocampo]]></surname>
<given-names><![CDATA[Ana L.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Juan-Romero]]></surname>
<given-names><![CDATA[Ana San]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital General del Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado Servicio de Cirugía ]]></institution>
<addr-line><![CDATA[ Querétaro]]></addr-line>
<country>México</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital General del Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado Cirugía Oncológica ]]></institution>
<addr-line><![CDATA[ Querétaro]]></addr-line>
<country>México</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2020</year>
</pub-date>
<volume>19</volume>
<fpage>6</fpage>
<lpage>9</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S2565-005X2020000500006&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S2565-005X2020000500006&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S2565-005X2020000500006&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen El melanoma maligno es el cáncer de piel que genera más muertes en el mundo. Esta alta mortalidad se debe a un alto potencial metastásico y a la pobre respuesta a las terapias sistémicas disponibles en etapas avanzadas. El tratamiento primario es quirúrgico. Alrededor de la mitad de los pacientes desarrollan metástasis gastrointestinales, pero solo un mínimo porcentaje tiene sintomatología. La presentación como apendicitis aguda de una metástasis es rara y la incidencia exacta es desconocida, se limita a una serie de reporte de casos. Presentamos a una paciente de 67 años con diagnóstico de melanoma maligno, tratada con resección quirúrgica, radioterapia e inmunoterapia; con presentación de apendicitis un año posterior al diagnóstico inicial. Siempre que se presente un paciente con cuadro sugestivo de abdomen agudo, con antecedente de melanoma maligno, incluso en remisión, se debe sospechar que sea una manifestación de una metástasis.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Malignant melanoma represents the first cause of death as a result of skin cancer on a global scale. This elevated mortality rate is due to its high metastatic potential and its poor response to systemic therapies available in advanced stages. Primary treatment is surgery. Half of all patients have gastrointestinal metastases, although only a minimum percentage presents symptoms. Metastasis presentation as acute appendicitis is rare and the exact incidence is unknown, it is limited to a series of case reports. We present a 67-year-old woman diagnosed with malignant melanoma, treated with surgical resection, radiotherapy and immunotherapy, who presented acute appendicitis one year after the initial diagnosis. Whenever a patient presents suggestive acute abdomen, with a history of malignant melanoma, even in remission, a manifestation of metastasis should be suspected.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Melanoma maligno]]></kwd>
<kwd lng="es"><![CDATA[Metástasis]]></kwd>
<kwd lng="es"><![CDATA[Apendicitis perforada]]></kwd>
<kwd lng="en"><![CDATA[Malignant melanoma]]></kwd>
<kwd lng="en"><![CDATA[Metastasis]]></kwd>
<kwd lng="en"><![CDATA[Perforated appendicitis]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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