<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0300-9041</journal-id>
<journal-title><![CDATA[Ginecología y obstetricia de México]]></journal-title>
<abbrev-journal-title><![CDATA[Ginecol. obstet. Méx.]]></abbrev-journal-title>
<issn>0300-9041</issn>
<publisher>
<publisher-name><![CDATA[Federación Mexicana de Colegios de Obstetricia y Ginecología A.C.]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0300-90412019000500311</article-id>
<article-id pub-id-type="doi">10.24245/gom.v87i5.2943</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Relación entre ácido úrico y composición corporal, perfil metabólico, leptina y adiponectina en mujeres posmenopáusicas]]></article-title>
<article-title xml:lang="en"><![CDATA[Relationship between uric acid and body composition, metabolic profile, leptin and adiponectin in postmenopausal women]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Saucedo]]></surname>
<given-names><![CDATA[Renata]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Peña-Cano]]></surname>
<given-names><![CDATA[María Isabel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Valencia]]></surname>
<given-names><![CDATA[Jorge]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Morales-Ávila]]></surname>
<given-names><![CDATA[Enrique]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Zavala-Moha]]></surname>
<given-names><![CDATA[José A.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[López]]></surname>
<given-names><![CDATA[Adriana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Hernández-Valencia]]></surname>
<given-names><![CDATA[Marcelino]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Mexicano del Seguro Social Centro Médico Nacional Siglo XXI ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Autónoma del Estado de México Facultad de Química ]]></institution>
<addr-line><![CDATA[ Estado de México]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Instituto Mexicano del Seguro Social Departamento de Oncología ]]></institution>
<addr-line><![CDATA[ Estado de México]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Instituto Mexicano del Seguro Social Departamento de Patología ]]></institution>
<addr-line><![CDATA[ Estado de México]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2019</year>
</pub-date>
<volume>87</volume>
<numero>5</numero>
<fpage>311</fpage>
<lpage>318</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0300-90412019000500311&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0300-90412019000500311&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0300-90412019000500311&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  OBJETIVO: Evaluar la relación del ácido úrico con los parámetros metabólicos, antropométricos, leptina y adiponectina, en mujeres posmenopáusicas en quienes se incrementa el riesgo de enfermedad cardiovascular.  MATERIALES Y MÉTODOS:  Estudio transversal y descriptivo efectuado en mujeres posmenopáusicas. Parámetros de estudio: mediciones antropométricas (bioimpedancia eléctrica), concentraciones de glucosa, colesterol total, LDL-colesterol, HDL-colesterol, triglicéridos (por métodos enzimáticos), adiponectina, leptina e insulina (por radioinmunoensayo). Cálculo de la resistencia a la insulina por el método HOMA-IR. Descripción de variables con promedio y desviación estándar. Análisis estadístico, con prueba de correlación de Pearson, para determinación de la relación entre el ácido úrico y las variables de estudio y regresión múltiple para determinación de los parámetros con mayor influencia en el ácido úrico.  RESULTADOS: Se estudiaron 90 mujeres posmenopáusicas de 55 a 84 años, con edad promedio de 63.7 años. La concentración promedio de ácido úrico de las participantes fue de 4.9 mg/dL. En el análisis bivariado los parámetros antropométricos, el LDL-c, los triglicéridos y la leptina se asociaron positivamente con el ácido úrico y el HDL-c y la adiponectina de forma negativa. En el análisis multivariado la grasa corporal se asoció con el ácido úrico, independientemente del peso corporal (beta = 0.592; p = 0.037).  CONCLUSIONES: En mujeres posmenopáusicas, las concentraciones anormales de ácido úrico se relacionan con un perfil cardiometabólico adverso.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  OBJECTIVE: To determine the relation between uric acid and metabolic and anthropometric parameters and adipokines leptin and adiponectin in post-menopausal women.  MATERIALS AND METHODS: A descriptive cross-sectional study was performed in post-menopausal women. Anthropometric measurements were taken by electric bioimpedance, and fasting venous blood samples were taken to determine glucose, total cholesterol, LDL-cholesterol, HDL-cholesterol and triglycerides by enzyme techniques, and levels of adiponectin, leptin and insulin were measured by radioimmunoassay. Insulin resistance was calculated using HOMA-IR. The variables were described with mean and standard deviation. Statistical analysis was performed by Pearson correlation test to evaluate the relation between uric acid and the study variables, and a multiple regression was performed to determine the parameters with greatest influence on uric acid.  RESULTS: The study included 90 post-menopausal women aged 55 to 84 years. The average age of the participants was 63.7 years, and the average concentration of uric acid was 4.9 mg/dL. In bivariate analysis, anthropometric parameters, LDL-cholesterol, triglycerides and leptin showed positive association with uric acid, and HDL-cholesterol and adiponectin had a negative one. In multiple regression analysis, body fat associated with uric acid independent of body weight (beta=0.592, p=0.037).  CONCLUSIONS: Uric acid relates with an adverse cardio-metabolic profile in post-menopausal women.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Ácido úrico]]></kwd>
<kwd lng="es"><![CDATA[posmenopausia]]></kwd>
<kwd lng="es"><![CDATA[peso corporal]]></kwd>
<kwd lng="es"><![CDATA[tejido adiposo]]></kwd>
<kwd lng="es"><![CDATA[colesterol]]></kwd>
<kwd lng="es"><![CDATA[triglicéridos]]></kwd>
<kwd lng="es"><![CDATA[resistencia a la insulina]]></kwd>
<kwd lng="en"><![CDATA[Uric acid]]></kwd>
<kwd lng="en"><![CDATA[Postmenopause]]></kwd>
<kwd lng="en"><![CDATA[Body weight]]></kwd>
<kwd lng="en"><![CDATA[Adipose tissue]]></kwd>
<kwd lng="en"><![CDATA[Cholesterol]]></kwd>
<kwd lng="en"><![CDATA[Triglycerides]]></kwd>
<kwd lng="en"><![CDATA[Insulin resistance]]></kwd>
</kwd-group>
</article-meta>
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