<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0188-4999</journal-id>
<journal-title><![CDATA[Revista internacional de contaminación ambiental]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Int. Contam. Ambient]]></abbrev-journal-title>
<issn>0188-4999</issn>
<publisher>
<publisher-name><![CDATA[Universidad Nacional Autónoma de México, Instituto de Ciencias de la Atmósfera y Cambio Climático]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0188-49992005000200063</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[EXPOSICIÓN A FTALATOS POR PROCEDIMIENTOS MÉDICOS EN VARONES RECIÉN NACIDOS]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Bustamante-Montes]]></surname>
<given-names><![CDATA[L. Patricia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[García-Fábila]]></surname>
<given-names><![CDATA[María Magdalena]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Martínez-Romero]]></surname>
<given-names><![CDATA[Evaristo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Vázquez-Moreno]]></surname>
<given-names><![CDATA[Flavio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Muñoz-Navarro]]></surname>
<given-names><![CDATA[Sergio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Karam-Calderón]]></surname>
<given-names><![CDATA[Miguel Ángel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ozorno-Torres]]></surname>
<given-names><![CDATA[Ramón]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Borja-Aburto]]></surname>
<given-names><![CDATA[Víctor Hugo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Autónoma del Estado de México Facultad de Medicina y Facultad de Química ]]></institution>
<addr-line><![CDATA[Toluca Edo. de México]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Instituto Nacional de Salud Pública  ]]></institution>
<addr-line><![CDATA[Cuernavaca Morelos]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Jiutepec  ]]></institution>
<addr-line><![CDATA[Jiutepec Morelos]]></addr-line>
<country>México</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Instituto Mexicano de Petróleo  ]]></institution>
<addr-line><![CDATA[México D.F.]]></addr-line>
<country>México</country>
</aff>
<aff id="Af5">
<institution><![CDATA[,Universidad de la Frontera  ]]></institution>
<addr-line><![CDATA[Temuco ]]></addr-line>
<country>Chile</country>
</aff>
<aff id="Af6">
<institution><![CDATA[,Instituto Mexicano del Seguro Social  ]]></institution>
<addr-line><![CDATA[Toluca Edo. de México]]></addr-line>
<country>Mexico</country>
</aff>
<aff id="Af7">
<institution><![CDATA[,Instituto Mexicano del Seguro Social  ]]></institution>
<addr-line><![CDATA[ D.F.]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2005</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2005</year>
</pub-date>
<volume>21</volume>
<numero>2</numero>
<fpage>63</fpage>
<lpage>69</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0188-49992005000200063&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0188-49992005000200063&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0188-49992005000200063&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN Aunque la exposición a plastificantes del grupo de los ftalatos es general en la población, se sospecha que algunos grupos de infantes pueden exponerse a niveles potencialmente tóxicos. Se realizó un estudio exploratorio observacional con el propósito de determinar si los plásticos empleados en procedimientos médicos invasivos exponen a los niños recién nacidos a ftalatos a niveles mayores a los observados en la población general. Se midieron las concentraciones urinarias de los metabolitos de los ftalatos más comúnmente empleados, ftalato de monometilo (FMM), ftalato de monobutilo (FMB), ftalato de monoetilhexilo (FMEH), ftalato de monoetilo (FME) y ftalato de monooctilo (FMO) en 30 recién nacidos sometidos a procedimientos de terapia intensi va neonatal y 30 niños del servicio de cunero que no recibieron ninguna intervención médica invasiva. La media del FMEH en orina de los niños sometidos a terapia intensiva neonatal fue de 46.82 &#956;g/L y de 5.19 &#956;g/L para los niños de cunero (p&lt; .001). El FMEH es el metabolito primario del ftalato de di-2(etilhexilo) (FDEH), principal plastificante utilizado en la fabricación de equipos médicos. Los resultados de este estudio exploratorio muestran elevados niveles de exposición en el grupo de recién nacidos sometidos a tratamientos en terapia intensiva neonatal comparados con el grupo de recién nacidos de cunero. El significado de esta exposición en la salud de estos niños es todavía incierto.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT Although human exposure to plasticizers such as phthalates is generalized, some infants could be exposed at potentially toxic levels. We performed an observational study to assess if infants under invasive medical procedures are more exposed to phthalates than the general population because of the plasticizers used in medical devices. Urinary metabolites concentrations of the most commonly used phthalates, monomethyl ph-thalate (MMP), monobutyl phthalate (MBP), mono2-(ethylhexyl) phthalate (MEHP), monoethyl phthalate (MEP) and monooctyl phthalate (MOP) were measured in 30 new-borns under intensive therapy and 30 newborns from the normal maternity room. Aver-age urine MEHP concentration was 46.82 &#956;g/L for newborns under intensive therapy and 5.19 &#956;g/L for children in maternity room (p &lt;0.001). MEHP is the primary metabolite of di-2(ethylhexyl) phthalate (DEHP), the main plasticizer used in medical devices. Results from this exploratory study show higher exposure levels in the group of newborns under neonatal intensive therapy as compared to newborns in maternity room. The health significance of this exposure remains uncertain.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[exposición a ftalatos]]></kwd>
<kwd lng="es"><![CDATA[CPV en tratamientos médicos]]></kwd>
<kwd lng="en"><![CDATA[phthalate exposure]]></kwd>
<kwd lng="en"><![CDATA[PVC in medical treatment]]></kwd>
</kwd-group>
</article-meta>
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<surname><![CDATA[Lambe]]></surname>
<given-names><![CDATA[J.C.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[The potential health effects of phthalate esters in children's toys: a review and risk assessment]]></article-title>
<source><![CDATA[Regul. Toxicol. Pharmacol.]]></source>
<year>1999</year>
<volume>30</volume>
<page-range>140-55</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
