<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0026-1742</journal-id>
<journal-title><![CDATA[Revista de la Facultad de Medicina (México)]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Fac. Med. (Méx.)]]></abbrev-journal-title>
<issn>0026-1742</issn>
<publisher>
<publisher-name><![CDATA[Universidad Nacional Autónoma de México, Facultad de Medicina]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0026-17422022000100040</article-id>
<article-id pub-id-type="doi">10.22201/fm.24484865e.2022.65.1.06</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Singulto persistente en dos pacientes con infección por SARS-CoV-2: reporte de casos y revisión de la literatura]]></article-title>
<article-title xml:lang="en"><![CDATA[Persistent Singult in Two Patients with SARS- CoV-2 Infection: Case Report and Literature Review]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Miguel-Álvarez]]></surname>
<given-names><![CDATA[Adriana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Instituto Mexicano del Seguro Social  ]]></institution>
<addr-line><![CDATA[Ciudad de México ]]></addr-line>
<country>Mexico</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>02</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>02</month>
<year>2022</year>
</pub-date>
<volume>65</volume>
<numero>1</numero>
<fpage>40</fpage>
<lpage>44</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0026-17422022000100040&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_abstract&amp;pid=S0026-17422022000100040&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.mx/scielo.php?script=sci_pdf&amp;pid=S0026-17422022000100040&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen En la actual pandemia por COVID-19, se han descrito manifestaciones poco frecuentes como la rabdomiólisis y la encefalomielitis aguda. Una de las presentaciones atípicas del SARS-CoV-2, es el singulto, que son contracciones repetitivas involuntarias de los músculos intercostales y del diafragma, cuyo origen puede ser gastrointestinal, neurogénico o infeccioso por tuberculosis e influenza, entre otros. En el presente reporte se describen los casos de 2 pacientes cuyo síntoma principal para el diagnóstico de infección por SARS-CoV-2 fue el singulto, asociado con un patrón de afección pulmonar bilateral; a propósito de los casos, se incluye una revisión en la literatura de diferentes pacientes y de los factores relacionados en cada uno.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract In the current COVID-19 pandemic, unusual manifestations such as rhabdomyolysis and acute encephalomyelitis have been described. One of the atypical presentations of COVID-19 is hiccups, which are involuntary repetitive contractions of the intercostal muscles and diaphragm, whose origin can be gastrointestinal, neurogenic, or infectious due to tuberculosis, influenza, among others. This report describes the cases of two patients in whom the main symptom for the diagnosis of SARS-CoV-2 infection, was hiccups associated with a pattern of bilateral pulmonary involvement; a review of the literature is included.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Singulto]]></kwd>
<kwd lng="es"><![CDATA[hiccups]]></kwd>
<kwd lng="es"><![CDATA[COVID-19]]></kwd>
<kwd lng="es"><![CDATA[SARS-CoV-2]]></kwd>
<kwd lng="es"><![CDATA[manifestaciones atípicas]]></kwd>
<kwd lng="en"><![CDATA[Singulto]]></kwd>
<kwd lng="en"><![CDATA[hiyccups]]></kwd>
<kwd lng="en"><![CDATA[COVID-19]]></kwd>
<kwd lng="en"><![CDATA[SARS-CoV-2]]></kwd>
<kwd lng="en"><![CDATA[atypical manifestations]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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