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Archivos de cardiología de México

versión On-line ISSN 1665-1731versión impresa ISSN 1405-9940

Arch. Cardiol. Méx. vol.93 no.3 Ciudad de México jul./sep. 2023  Epub 04-Sep-2023

https://doi.org/10.24875/acm.23000079 

Letters to the editor

Acute myocarditis after administration of COVID-19 vaccine: comment

Miocarditis aguda tras administración de COVID-19 vacuna: comentario

Amnuay Kleebayoon1  * 

Viroj Wiwanitkit2  3 

1Consultant Unit, Private Academic Consultant, Samraong, Cambodia

2Research Center, Chandigarh University, Punjab, India

3Joesph Ayobabalola University, Ikeji-Arakeji, Nigeria


Dear Editor

We would like to share ideas on the publication “Acute myocarditis after administration of BNT162b2 vaccine against COVID-191”. Cueva-Recalde et al. present the case of a 28-year-old male patient with no prior medical history who has been experiencing chest pain for the past 3 days1. The patient was hospitalized but remained asymptomatic and did not require treatment1. Cueva-Recalde et al. stated that, while rare, physicians should be aware of this adverse event of COVID-19 vaccination, while bearing in mind its unquestionably positive benefit-risk profile1.

We both agree that protecting the COVID-19 is essential and that more study is required to address the major clinical problem. The development of clinical diseases and immunization may be causally related. It might occasionally be difficult to identify the specific path-immunopharmacological link due to ignorance. If a clinical condition is thought to be related to the COVID-19 immunization, there are a few important factors that need to be taken into account. There is a chance of comorbidity. For instance, a concurrent dengue infection and vaccination could result in a clinical illness that was misdiagnosed2. Comorbidity is a likely ailment that might be misdiagnosed as a negative vaccination reaction. It may be difficult to understand how therapy methods are impacted by chronic medical conditions. It could be difficult to understand how persistent medical issues affect therapeutic strategies. The COVID-19, which is currently unidentified, must also be considered3.

It is conceivable that a previous COVID-19 pandemic had an impact on the vaccine's efficiency and results. Infection with COVID-19 may also have an impact on clinical outcomes. It is often challenging to completely rule out the effects of earlier asymptomatic illnesses without the required laboratory investigations. An important auxiliary factor is genetics4. The immune system's response to certain genetic components may affect how it handles negative vaccine side effects. Understanding how the underlying genetic component impacts the clinical scenario regarding vaccine success would be very beneficial. This problem needs to be resolved if more research is to be done. Summative large-scale data may help researchers better comprehend the COVID-19 vaccine's effects.

References

1. Cueva-Recalde JF, Ibáñez-Muñoz D, Meseguer-González D, Sola-Moreno T, Yanguas-Barea N, Ruiz-Arroyo JR. Acute myocarditis after administration of BNT162b2 vaccine against COVID-19. Arch Cardiol Mex. 2023;93:243-5. [ Links ]

2. Kebayoon A, Wiwanitkit V. Dengue after COVID-19 vaccination:possible and might be missed. Clin Appl Thromb Hemost. 2021;27:10760296211047229. [ Links ]

3. Joob B, Wiwanitkit V. Letter to the editor:coronavirus disease 2019 (COVID-19), infectivity, and the incubation period. J Prev Med Public Health. 2020;53:70. [ Links ]

4. ČiučiulkaitėI, Möhlendick B, Thümmler L, Fisenkci N, Elsner C, Dittmer U, et al. GNB3 c.825c>T polymorphism influences T-cell but not antibody response following vaccination with the mRNA-1273 vaccine. Front Genet. 2022;13:932043. [ Links ]

FundingNone.

Ethical disclosures

Protection of human and animal subjects. The authors declare that no experiments were performed on humans or animals for this study.

Confidentiality of data. The authors declare that no patient data appear in this article.

Right to privacy and informed consent. The authors declare that no patient data appear in this article.

Use of artificial intelligence for generating text. The authors declare that they have not used any type of generative artificial intelligence for the writing of this manuscript nor for the creation of images, graphics, tables, or their corresponding captions.

Received: April 11, 2023; Accepted: May 16, 2023

* Correspondence: Amnuay Kleebayoon E-mail: amnuaykleebai@gmail.com

Conflicts of interest

None.

Creative Commons License Instituto Nacional de Cardiología Ignacio Chávez. Published by Permanyer. This is an open ccess article under the CC BY-NC-ND license