Revisión

 

Técnicas biomagnéticas y su comparación con los métodos bioeléctricos

 

M. Sosa¹, J. J. Bernal Alvarado¹, J. L. González¹, G. Gutiérrez Juárez¹, M. Vargas Luna¹, C. Caudillo-Cisneros², S. Márquez Gamiño², R. Huerta³

 

¹ Instituto de Física, Universidad de Guanajuato Apdo. Post. E-143, 37000 León, Gto., México.

² Instituto de Investigación sobre el Trabajo, Universidad de Guanajuato Apdo. Post 1-607, 37000 León, Gto., México.

³ Instituto de Investigaciones Médicas, Universidad de Guanajuato Apdo. Post 874, 37320 León, Gto., México.

 

Recibido el 14 de mayo de 2002.
Aceptado el 22 de julio de 2002.

 

Resumen

Los seres vivos son capaces de generar campos magnéticos. Actualmente, estos campos, a pesar de ser muy débiles, pueden ser detectados por instrumentos sofisticados, lo que abre un nuevo campo de investigación. Estudios recientes sobre este fenómeno revelan que la detección y el análisis de los campos generados en órganos como el cerebro, corazón, pulmones, hígado y otros, pueden facilitar el diagnóstico y los tratamientos de diversas enfermedades, entre otras aplicaciones. En este trabajo se presenta una comparación entre las técnicas biomagnéticas y los métodos bioeléctricos estándares. El trabajo enfatiza la importancia del uso de ambas técnicas como métodos complementarios de investigación y su utilidad en el diagnóstico de enfermedades y resalta el hecho de que ambas están basadas en los mismos principios físicos.

Descriptores: Biomagnetismo; magnetobiología; bioelectricidad.

 

Abstract

Biological systems are able to generate magnetic fields. Despite these fields being so weak, now it is possible to detect them by means of sophisticated equipments, which opens a new research field. Recent studies on this phenomenon reveal that the measurement and analysis of the fields, generated in organs such as the brain, heart, lungs, liver, etc., can be useful in the detection and treatment of several sickness, among other applications. In this work a comparison between biomagnetic and standard bioelectric techniques is provided. The work emphasizes the importance of using both techniques as complementary methods in research and their usefulness in the diagnostic of pathologies and stand out the fact that both methods are based on the same physical principles.

Keywords: Biomagnetism; magnetobiology; bioelectricity.

 

PACS: 87.01A; 85.25; 06.30Lz

 

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Referencias

1. R. Iannini, Med. Secoli 4 (1992) 71.         [ Links ]

2. S.J. Williamson and L. Kaufman, J. Magnetism and Magnetic Materials 22 (1981) 129.         [ Links ]

3. K.G. Blaasaas, T. Tynes, A. Irgens and R.T. Lie, Occupational & Enviromental Medicine 59 (2002) 92.         [ Links ]

4. D. Halliday, R. Resnick and K.S. Krane, Física. Vol. 2. (Compañía Editorial Continental, México, 1996).         [ Links ]

5. A.A.O. Carneiro, A. Ferreira, E.R. Moraes, D.B. Araujo, M. Sosa and O. Baffa, Rev. Bras. Ens. Fís. 22 (2000) 324.         [ Links ]

6. E.A.C. García, Biofísica (SARVIER, São Paulo, 1997).         [ Links ]

7. M. Hamalainen, R. Hari, R.J. Ilmoniemi, J. Knuutila and O.V. Lounasmaa, Rev. Mod. Phys. 65 (1993) 413.         [ Links ]

8. G.M. Baule and R. McFee, Am. Heart. J. 66 (1963) 95.         [ Links ]

9. A.A. Carneiro, O. Baffa and R.B. Oliveira, Phys. Med. Biol. 42 (1997) 1791.         [ Links ]

10. D. Cohen, Science 180 (1973) 745.         [ Links ]

11. W. Andra and H. Nowak, Magnetism in medicine: A handbook (Wiley and Sons, New York, 1998).         [ Links ]

12. F. Pasemann, Network 13 (2002) 195.         [ Links ]

13. C. Baumgartner and L Deecke, Brain Topography 2 (1990) 203.         [ Links ]

14. R.C. Knowlton, K.D. Laxer, M.J. Aminoff, T. Roberts, S. Wong and H.A. Rowley, Ann. Neurol. 42 (1997) 622.         [ Links ]

15. R.R. Fenici, D. Brisinda, P. Fenici, G. Morana and M.P. Ruggieri, Proc. of the 12^thInternational Conf. on Biomagnetism, edited by J. Nenonen, R.J. Ilmoniemi and T. Katila (Helsinki, 2001) p. 542.         [ Links ]

16. P.M. Rossini, F. Tecchio, V. Pizzella, D. Lupoi, E. Cassetta, P. Pasqualetti and P. Paqualetti, Neuroimage 14 (2001) 474.         [ Links ]

17. M. Balish, S. Sato, P. Connaughton, and C. Kufta, Neurology 41 (1991) 1072.         [ Links ]

18. D. Cohen et al., Ann. Neurol. 28 (1990) 811.         [ Links ]

19. R.P. Crease, Science 253 (1991) 374.         [ Links ]

20. B.N. Cuffin etal., Ann. Neurol. 29 (1991) 132.         [ Links ]

21. J. Malmivuo, Med. & Biol. Eng. & Comput. 18 (1980) 365.         [ Links ]

22. J. Malmivuo, Proc. of the 2^nd Far Eastern Conf. Medical and Biological Engineering (Beijing, 1993) p. 370.         [ Links ]

23. J. Malmivuo and R. Plonsey, Bioelectromagnetism - Principles and applications of bioelectric and biomagnetic fields (Oxford University Press, New York, 1995) p. 480.         [ Links ]

24. V. Suihko and J. Malmivuo, Proc. of the 2^nd Ragnar Granit Symp. , (Tampere, 1993) p. 11.         [ Links ]

25. J.P. Wikswo, A. Gevins and S.J. Williamson, Electroenceph. Clin. Neurophysiol. 87 (1993) 1.         [ Links ]

26. R. Hari, M. Hamalainen, R.J. Ilmoniemi and O.V. Lounasmaa, Ann. Neurol. 30 (1991) 222.         [ Links ]

27. S. Williamson, Ann. Neurol. 30 (1991) 222.         [ Links ]

28. G. Anogianakis et al., Electroencephalogr. Clin. Neurophysiol. 82 (1992)317.         [ Links ]

29 . S. Van den Noort et al., Report of the therapeutics and technology assessment. Subcommittee of the American Academy of Neurology (1992).         [ Links ]

30. T. Yamamoto, S.J. Williamson, L. Kaufman, C. Nicholson and R. Linas, Proc. Natl. Acad. Sci. USA 85 (1988) 8732.         [ Links ]

31. J. Malmivuo, IEEE Trans. Biomed. Eng. 44 (1997) 196.         [ Links ]

32. F. Babiloni et al., Hum. Brain Mapp. 14 (2001) 197.         [ Links ]

33. J.S. George, P.S. Jackson, D.M. Ranken and E.R. Flynn, in Advances in Biomagnetism, edited by S.J. Williamson, M. Hoke, G. Stroink and M. Kotani, (Plenum, New York, 1989).         [ Links ]

34. S. Schneider et al., in Advances in Biomagnetism, edited by S.J. Williamson, M. Hoke, G. Stroink and M. Kotani, (Plenum, New York, 1989).         [ Links ]

35. J. Suk, J. Cappell, U. Ribary, T. Yamamoto and R.R. Linas, in Advances in Biomagnetism, edited by S.J. Williamson, M. Hoke, G. Stroink and M. Kotani, (Plenum, New York, 1989).         [ Links ]

36. M. Hamalainen, Clin. Phys. Physiol. Meas. Suppl. A12 (1991) 29.         [ Links ]

37. I. Chaikovsky et al., Proc. of the 12^th International Conf. on Biomagnetism, edited by J. Nenonen, R.J. Ilmoniemi and T. Katila (Helsinki, 2001) p. 565.         [ Links ]

38. M. Makijarvi, J. Montonen, L. Toivonen, P. Siltanen, M.S. Nieminen, M. Leinio and T. Katila, J. Electrocardiol. 26 (1993) 117.         [ Links ]

39. S. Uchida, K. Goto, A. Tachikawa, K. Iramina and S. Ueno, Proc. of the 12^th International Conf. on Biomagnetism, edited by J. Nenonen, R.J. Ilmoniemi and T.         [ Links ]

40. Katila (Helsinki, 2001) p. 534.         [ Links ]

41. M. Makijarvi, Herzschr. Elektrophys. 8 (1997) 178.         [ Links ]

42. P. Korhonen, J. Montonen, M. Paavola, M. Mäkijärvi and T. Katila, Eur. Heart J. 17 (1996) 502.         [ Links ]

43. V. Kariniemi, J. Ahopelto, P.J. Karp and T.E. Katila, J. Perinat. Med. 2 (1974)412.         [ Links ]

44. P. Van Leeuwen, Herzschr. Elektrophys. 8 (1997) 184.         [ Links ]

45. G.L. Romani, S.J. Williamson and L. Kaufman, Rev. Sci. Instr. 53 (1982) 1815.         [ Links ]

46. R. Wakai, A. Leuthold, A. Wilson and C. Martin, Pediatr. Cardiol. 18 (1997) 201.         [ Links ]

47. P. Van Leeuwen, B. Hailer, W. Bader, J. Geissler, E. Trowitzsch and D. Grönemeyer, Br. J. Obstet. Gynaecol. 106 (1999) 1200.         [ Links ]

48. R.T. Wakai, A.C. Leuthold and C.B. Martin, Am. J. Obstet. Gynecol. 179 (1998)258.         [ Links ]

49. H. Hamada et al., Prenat. Diagn. 19 (1999) 677.         [ Links ]

50. O. Kosch, P. Meindl, U. Steinhoff and L. Trahms, Proc. of the 12^th International Conf. on Biomagnetism, edited by J. Nenonen, R.J. Ilmoniemi and T. Katila (Helsinki, 2001) p. 553.         [ Links ]

51. P.C. Franzone, L. Guerri, M. Pennacchio and B. Tarcadi, Math. Biosci. 147 (1998) 131.         [ Links ]

52. T. Nakadate, Y. Aizawa, T. Yagami, Y. Zhen, M. Kotani and K. Ishiwata, Occup. Env. Med. 55 (1998) 673.         [ Links ]

53. S.J. Swithenby, in Advances in Biomagnetism, edited by S.J. Williamson, M. Hoke, G. Stroink and M. Kotani, (Plenum, New York, 1989).         [ Links ]

54. D.E. Farrell, The magnetic biopsy. Biomagnetism. An interdisciplinary approach (Plenum Press, New York, 1983).         [ Links ]

55. G.M. Brittenham et al., Il Nuovo Cimento 2D (1983) 567.         [ Links ]

56. D.N. Paulson, R. Engelhardt, R. Fischer and H.C. Heinrich, in Advances in Biomagnetism, edited by S.J. Williamson, M. Hoke, G. Stroink and M. Kotani, (Plenum, New York, 1989).         [ Links ]

57. W. Weitschies, J. Wedemeyer, R. Stehr and L. Trahms, IEEE Trans. Biomed. Eng. 41 (1994) 192.         [ Links ]

58. E.H. Frei, Y. Benmair, Y. Yerashalmi and F. Dreyfuss, IEEE Trans. Magn. 6 (1970) 348.         [ Links ]

59. Y. Benmair, F. Dreyfuss, B. Fischel, E.H. Frei and T. Gilat, Gastroenterology 73 (1977) 1041.         [ Links ]

60. A.A.O. Carneiro, O. Baffa and R.B. Oliveira, Fís. Med. Biol. 44 (1999) 1691.         [ Links ]

61. M. Forsman, Med. Biol. Eng. Comput. 38 (2000) 169.         [ Links ]

62. M. Sosa, A.A.O. Carneiro, J.F. Colafemina and O. Baffa, J. Magnetism and Magnetic Materials 226 (2001) 2067.         [ Links ]

63. J.E. Zimmerman, in Advances in Biomagnetism, edited by S.J. Williamson, M. Hoke, G. Stroink and M. Kotani, (Plenum, New York, 1989).         [ Links ]

64. K. Tsukada, J. Kawai, Y. Takada and A. Adachi, IEEE Trans. Appl. Superconduct. 5 (1995) 3488.         [ Links ]

65. H.E. Hoenig, G.M. Daalmans, L. Bär, F. Bömmel, A. Paulus, D. Uhl and H.J. Weisse, IEEE Trans. Magnetics 27 (1991) 2777.         [ Links ]

66. T. Takeda and T. Takae, Proc. of the 12^th International Conf. on Biomagnetism, edited by J. Nenonen, R.J. Ilmoniemi and T. Katila (Helsinki, 2001) p. 951.         [ Links ]

67. D. Cohen, Appl. Phys. Lett. 16 (1970) 278.         [ Links ]

68. M. Koyanagi, N. Kasai, K. Chinone, M. Nakanishi and S. Kosaka, IEEE Trans Magnetics 25 (1989) 1166.         [ Links ]

69. G. Kajiwara, K. Harakawa and H. Ogata, IEEE Trans. Mag. 32 (1996) 2582.         [ Links ]

70. N. Weiskopf, C. Braun and K. Mathiak, Proc. ofthe 12^th International Conf. On Biomagnetism, edited by J. Nenonen, R.J. Ilmoniemi and T. Katila (Helsinki, 2001) p. 500.         [ Links ]

71. R.J. Ilmoniemi, Brain Topography 15 (1993) 331.         [ Links ]

72. U. Tenner, J. Haueisen, H. Nowak, U. Leder and H. Brauer, Phys. Med. Biol. 44 (1999) 1969.         [ Links ]

73. C.J. Stok, IEEE Trans. Biomed. Eng. 34 (1987) 289.         [ Links ]

74. T. Kawamura, N. Nakasato, K. Seki, A. Kanno, S. Fujita, S. Fujiwara and T. Yoshimoto, Electroencephal. And Clin. Neurophysiol. 100 (1996)44.         [ Links ]

75. A.M. Dale and M.I. Sereno, J. Cognit. Neurosci. 5 (1993) 162.         [ Links ]