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Gaceta médica de México

versión On-line ISSN 2696-1288versión impresa ISSN 0016-3813

Gac. Méd. Méx vol.156 no.4 Ciudad de México jul./ago. 2020  Epub 27-Mayo-2021

https://doi.org/10.24875/gmm.m20000399 

Artículos originales

Symptoms of anxiety and depression and self-care behaviors during the COVID-19 pandemic in the general population

Síntomas de ansiedad, depresión y conductas de autocuidado durante la pandemia de COVID-19 en la población general

Oscar Galindo-Vázquez1  * 

Mónica Ramírez-Orozco2 

Rosario Costas-Muñiz3 

Luis A. Mendoza-Contreras1 

Germán Calderillo-Ruíz4 

Abelardo Meneses-García5 

1Instituto Nacional de Cancerología, Psycho-Oncology Department, Mexico City, Mexico

2Universidad Nacional Autónoma de México, Faculty of Psychology, Mexico City, Mexico

3Memorial Sloan-Kettering Cancer Center, Department of Psychiatry and Behavioral Sciences, New York, United States

4Instituto Nacional de Cancerología, Internal Medicine Sub-directorate, Mexico City, Mexico

5Instituto Nacional de Cancerología, General Directorate, Mexico City, Mexico


Abstract

Introduction:

The COVID-19 pandemic can have important psychosocial consequences in the population.

Objective:

To determine the levels anxiety and depression symptoms and self-care behaviors during the COVID-19 pandemic in the general population.

Method:

Online survey distributed over three weeks using a non-probability sampling. The PHQ-9 Patient Health Questionnaire, the GAD-7 Generalized Anxiety Disorder Scale and a self-care behaviors visual analogue scale were used. Between-group (anxiety and depression) descriptive and comparison analyses were carried out.

Results:

Out of 1508 included participants, 20.8 % had symptoms of severe anxiety, while 27.5 % showed symptoms of severe depression. Being a woman, being single, having no children, having medical comorbidities and a history of mental health care were associated with the presence of higher levels of anxiety and depression symptoms; 66 to 80 % of the population complied with self-care recommendations. A need for receiving mental health care was identified in our study population.

Conclusion:

A larger number of individuals with moderate to severe anxiety and depression symptoms were observed than in other pandemics. COVID-19 pandemic psychological effects are considered an emerging public mental health problem, and implementation of programs for their care is therefore recommended.

KEY WORDS Anxiety; COVID-19; Depression; Pandemic

Resumen

Introducción:

La pandemia por COVID-19 puede tener consecuencias psicosociales importantes en la población.

Objetivo:

Determinar los niveles de síntomas de ansiedad, depresión y conductas de autocuidado durante la pandemia de COVID-19 en población general.

Método:

Encuesta en línea distribuida durante tres semanas mediante muestreo no probabilístico. Se empleó el Cuestionario sobre la Salud del Paciente PHQ-9, la Escala del Trastorno de Ansiedad Generalizada GAD-7 y la Escala análoga visual de conductas de autocuidado. Se realizaron análisis descriptivos y de comparación entre los grupos con ansiedad y depresión.

Resultados:

Se incluyeron 1508 participantes, 20.8 % presentó síntomas de ansiedad grave y 27.5 %, síntomas de depresión grave. Ser mujer, soltero(a) no tener hijos, presentar comorbilidad médica y antecedentes de atención a la salud mental estuvieron relacionados con la presencia de mayores niveles de síntomas de ansiedad y depresión; 66 a 80 % de la población cumplía con las recomendaciones de autocuidado. Se identificó la necesidad de recibir atención de salud mental.

Conclusión:

Se observó mayor número de individuos con síntomas de ansiedad y depresión moderadas a graves que en otras pandemias. Los efectos psicológicos de la pandemia de COVID-19 se consideran un problema de salud mental pública emergente, por lo que se recomienda la implementación de programas para su atención.

PALABRAS CLAVE Ansiedad; COVID-19; Depresión; Pandemia

Introduction

The COVID-19 pandemic has brought not only the risk of transmission and infection-related death, but also important psychological effects.1 Psychological factors are known to play a vital role in the success of public health strategies that are used to control epidemics and pandemics, as well as in the communication of risks, vaccination and antiviral therapy, hygiene practices and social distancing.2-4

Pandemics, such as that of severe acute respiratory syndrome (SARS), have been reported to be stressful situations that threaten physical health and psychological well-being, in addition to causing disruptions in interpersonal functioning and the perception that transmission is relatively uncontrollable even when measures that reduce the risk are taken (for example, wearing masks, avoiding crowds).5

In viral outbreaks, a person with severe anxiety can misinterpret benign muscle aches or cough as signs of infection, as well as developing maladaptive behaviors such as compulsive handwashing, social withdrawal and panic shopping, which can have negative consequences for the individual and his/her community. For example, a sense of urgency for products that are needed for quarantine can lead to overspending in the storage of resources and harm to the community, which needs such resources for other purposes, including medical care.3 On the other hand, people who consider themselves to be at low risk of infection are unlikely to change their behavior and follow the social distancing recommendations, with the consequent negative impact on efforts to mitigate the dissemination of the virus.

With regard to reported psychological symptoms, mild anxiety was identified in 21.3 % of 7143 college students exposed to COVID-19; in 2.7 %, moderate anxiety, and in 0.9 %, severe anxiety. Living in urban areas and with the parents were protective factors against anxiety. Having relatives or acquaintances infected with COVID-19, unstable financial situation and backlog in academic activities were associated with higher anxiety (p < 0.001). Social support was negatively correlated with the level of anxiety (p < 0.001).1

Moderate to severe or severe anxiety and/or depression symptoms were identified in 35 % of 180 SARS survivors one month after recovery. Health workers or those who had relatives who died because of SARS were more likely to develop high levels of distress.6

When hospital health workers (n = 82) were compared during the peak of the epidemic with hospital staff who recovered from SARS (n = 97), both groups were found to have the same level of concern about infecting others (especially their family members). Workers were more afraid of infection; in survivors, SARS-related fear was correlated with post-traumatic stress symptoms; in addition, they expressed concern about other health problems and discrimination (p < 0.05).7 People who have experienced public health emergencies have varying degrees of stress, even after the event has ended or they have recovered and been discharged from hospital.6,8

Taking into account social interaction restrictions and confinement measures, mental health services have adopted the use of hotlines, mobile application platforms, the internet and social networks to share strategies for dealing with stress,9 as well as for assessing the psychosocial impact on exposed population. Therefore, the purpose of this research was to determine the levels of anxiety and depression symptoms, as well as self-care behaviors, during the COVID-19 pandemic in the general population.

Method

A non-experimental, cross-sectional study was carried out,10 for which an online survey was conducted using a non-probabilistic convenience sampling; 1508 male and female participants from Mexico and abroad were included. As inclusion criteria, a minimum age of 12 years and knowing how to read and write were considered. Individuals with cognitive impairment that prevented them from answering the survey were excluded, and those who during or after completing the survey decided not to continue participating were removed from the investigation.

An identification card was designed, which included sociodemographic and clinical data. The following evaluation instruments were used:

  • – Patient Health Questionnaire-9 (PHQ-9). The Patient Health Questionnaire-9 (PHQ-9), developed by Kroenke et al. in 2001,11 is a screening tool that assesses the possible presence of major depressive disorder and the severity of depression symptoms. Its structure is one-dimensional, it has nine items based on Statistical Manual of Mental Disorders, Fourth edition, Text Revision (DSM IV TR) criteria and a global Cronbach’s alpha of 0.89. It was validated in the Mexican population,*1 with an internal consistency of 0.86 and an explained variance of 47 %.

  • – Generalized Anxiety Disorder-7 Scale (GAD-7). Developed by Spitzer et al. in 2006,12 it is a screening tool that assesses the presence of possible generalized anxiety disorder. It has a one-dimensional structure of seven items based on DSM IV TR criteria, which explain 63 % of variance, and a global Cronbach’s alpha of 0.92. It was validated in the Mexican population,* with an internal consistency of 0.88 and an explained variance of 57.72 %.

  • – Self-care behaviors visual analogue scale. Behaviors were assessed using a 10-point visual analogue scale, where 0 means “I do not follow the recommendation at all” and 10 means “I follow the recommendation all the time”, which specify how individuals carried out self-care strategies.

Sample collection was carried out from March 26 to April 12, 2020. The purpose of the investigation, its procedure, data confidentiality, as well possible risks and benefits, were explained to each participant by electronic means. All individuals voluntarily participated and granted written consent. The procedures of this investigation complied with the provisions of the Declaration of Helsinki with regard to research in human subjects.

Data were analyzed with SPSS version 22.0. Descriptive analysis of central tendency and dispersion measures was carried out to illustrate demographic and clinical characteristics, as well as univariate analysis to identify the differences between sociodemographic variables and the level of anxiety and depression symptoms. Normality of variables was determined by means of Kolmogorov-Smirnov goodness-of-fit test (p < 0.001), whereby a non-normal distribution was observed; therefore, medians and non-parametric Mann-Whitney U and Kruskal-Wallis tests were used.13 Finally, Pearson’s correlation analysis was carried out. A p-value < 0.05 was established as statistically significant.

Results

As it can be observed in Table 1, total sample consisted of 1508 participants, 1,123 women and 385 men, with an average age of 34 years; 61.3 % were childless, 50.8 % were single, 55.2 % had a college degree, 35.6 % worked as professionals and 24 % referred having some chronic degenerative disease.

Table 1 Characteristics of the surveyed individuals with regard to symptoms of depression and anxiety during the COVID-19 pandemic (n = 1508) 

Age (years) Mean = 34.46; range 18-82
n % n %
Gender Level of education
Females 1123 74.5 Basic education 34 2.3
Males 385 25.5 High school 209 13.9
Country College degree 833 55.2
Mexico 1421 94.2 Postgraduate 406 26.9
Other 87 5.8 Other 26 1.7
Marital status Occupation
Single 817 54.2 Homemaker 58 5.8
Married 397 26.3 Student 256 25.6
Widower 17 1.1 Employee 254 25.4
Divorced or separated 111 7.4 Unemployed 48 4.8
Cohabitation 157 10.4 Professional 356 5.6
Other 9 0.6 Retired 27 2.7
Paternity Residence in Mexico (n = 1426)
Yes 583 38.7 Mexico City 688 42.8
No 925 61.3 State of Mexico 265 18.6
Medical comorbidity (n = 417) Other states 473 33.2
Hypertension 85 20.4 Disease
Diabetes 43 10.3 Yes 400 26.5
Cancer 29 7.0 No 1108 73.5
Depression 75 18
Anxiety 116 27.8 Health insurance
Other 196 47.0 Yes 1035 68.6
No 473 31.4
Prior mental health care
Yes 929 61.6
No 579 38.4

Different behavioral areas related to the contingency and its psychosocial consequences were explored. Most participants (92 %) referred that they would undergo the test for COVID-19 detection, whereas 90 % did not have any relative or friend with the virus infection at that moment.

Regarding self-care behaviors, adequate adherence to recommendations stood out, since 80 % complied with not attending meetings or crowded places, 88 % frequently washed or disinfected their hands, 66 % kept the recommended distance (1.5 to 2 m) and 72 % stayed home.

As for coping strategies, 41 % cared little about getting sick, approximately 15 % were frequently worried about getting the disease, while 31 % continually analyzed their bodily sensations, interpreting them as symptoms of the disease. Half the participants frequently used past stressing experience strategies to reduce fear and generated a list of activities to stay active; the same percentage claimed that they maintained an optimistic and objective attitude towards the situation, as well as to have support networks to talk and solve problems (Table 2).

Table 2 Coping and self-care behaviors in the face of the COVID-19 pandemic in surveyed individuals with regard to symptoms of depression and anxiety 

Never Rarely Frequently Almost always Always
n % n % n % n % n %
How often do you worry about getting infected with COVID-19? 7.4 6.9 629 41.7 523 34.7 164 10.9 81 5.4
Are you continually analyzing and interpreting your bodily sensations as symptoms of disease? 329 21.8 704 46.7 340 22.5 84 5.6 51 3.4
Do you feel frustrated by the effects COVID-19 has had on your life? 207 13.7 585 38.8 436 28.9 185 12.3 95 6.3
When you are afraid, do you rely on experiences you have had in similar situations to reduce fear? 140 9.3 361 23.9 437 29.0 365 24.2 205 13.6
You generate a list of daily activities and try to keep busy 138 9.2 302 20.0 390 25.9 390 25.9 288 19.1
You maintain an optimistic and objective attitude towards the situation 20 1.3 134 8.9 423 28.1 521 34.5 410 27.2
You have someone you can lean on or with whom you can talk about your problems 40 2.7 200 13.3 244 16.2 341 22.6 683 45.3
Visual analogue scale score
0-1 2-3 4-5 6-7 8-10
n % n % n % n % n %
How much have you followed the following recommendations?
− Not attending social gatherings or crowded places 44 2.9 44 2.9 82 5.4 92 6.8 1236 82.0
− Washing or disinfecting your hands frequently 10 0.7 12 0.8 40 2.7 97 6.4 1349 89.4
− Keeping at least 1.5 m away from other people 64 4.3 46 3.3 167 11.1 225 26.3 1006 66.8
− Staying home 97 6.5 49 3.3 120 7.9 123 8.8 1109 73.0

As regards specific needs to face the current health problem, 68 % answered that having information about the disease was essential, as well as knowing the health institutions they can attend and covering the economic needs for subsistence; 34 % considered it necessary for the psychological aspect to be taken care of (Figure 1).

Figure 1 Perceived aspects for adapting to the COVID-19 pandemic. 

The anxiety and depression symptom scores had means of 12.35 and 14.4, respectively. The fact that 20.8 % had symptoms of severe anxiety, and 27.5 %, of severe depression, stood out (Table 3). Participants without children, with medical conditions and a history of mental health care were observed to have higher levels of depression and anxiety (p <0.001). Specifically, the female gender reported higher levels of anxiety, and single individuals, higher levels of depression (p <0.001) (Tables 4 and 5).

Table 3 Level of COVID-19 pandemic-derived anxiety and depression 

Anxiety Depression
Level n % Level n %
Minimal 525 34.8 Minimal 598 39.7
Mild 253 16.8 Mild 337 22.3
Moderate 416 27.6 Moderate 158 10.5
Severe 314 20.8 Severe 415 27.5
Total 1508 100.0 Total 1508 100.0

Table 4 Sociodemographic variables comparison between participants with symptoms of anxiety (n = 1508) 

Variable GAD-7 score
Minimal Mild Moderate Severe Total p
n % n % n % n % n %
Gender
Females 352 67 199 78.7 316 76 256 81.5 1123 74.5 < 0.001
Males 173 33 54 21.3 100 24 58 18.5 385 25.5
Paternity
Yes 223 42.5 98 38.7 158 38 104 33.1 583 38.7 0.008
No 302 57.5 155 61.3 258 62 210 66.9 925 61.3
Marital status
Single 268 51 142 56.1 215 51.7 192 61.1 817 54.2 0.151
Married 145 27.6 71 28.1 112 26.9 69 22.0 397 26.3
Widowed 9 1.7 3 1.2 4 1.0 1 0.3 17 1.1
Divorced/separated 40 7.6 19 7.5 28 6.7 24 7.6 111 7.4
Cohabitation 60 11.4 17 6.7 54 13 26 8.3 157 10.4
Other 3 0.6 1 0.4 3 0.7 2 0.6 9 0.6
Disease
Yes 105 20 58 22.9 105 25.2 132 42 400 26.5 < 0.001
No 420 80 195 77.1 311 74.8 182 58 1108 73.5
Place of residence
Mexico City 237 48 122 50.6 178 45.3 151 50.7 688 48.2 0.645
State of Mexico 87 17.6 45 18.7 75 19.1 58 19.5 265 18.6
Another state 170 34.4 74 30.7 140 35.6 89 29.9 473 33.2
Medical insurance
Yes 348 66.3 180 71.1 278 66.8 229 72.9 1035 68.6 0.120
No 177 33.7 73 28.9 138 33.2 85 27.1 473 31.4
Previous mental health care
Yes 265 50.5 155 61.3 274 65.9 235 74.8 929 61.6 < 0.001
No 260 49.5 98 38.7 142 34.1 79 25.2 579 34.8

GAD-7 = Generalized Anxiety Disorder-7.

Table 5 Sociodemographic variables comparison between participants with symptoms of depression (n = 1508) 

Variable PHQ-9 score
Minimum Mild Moderate Severe Total p
n % n % n % n % n %
Gender
Females 429 71.7 247 73.3 127 80.4 320 77.1 1123 74.5 0.024
Males 169 28.3 90 26.7 31 19.6 95 22.9 385 25.5
Paternity
Yes 285 47.7 124 36.8 51 32.3 123 29.6 583 38.7 < 0.001
No 313 52.3 213 63.2 107 67.7 292 70.4 925 61.3
Marital status
Single 274 45.8 175 51.9 95 60.1 273 65.8 817 54.2 < 0.001
Married 196 32.8 94 27.9 39 24.7 68 16.4 397 26.3
Widowed 10 1.7 1 0.3 0 0.0 6 1.4 17 1.1
Divorced/separated 45 7.5 23 6.8 9 5.7 34 8.2 111 7.4
Cohabitation 69 11.5 42 12.5 14 8.9 32 7.7 157 10.4
Other 4 0.7 2 0.6 1 0.6 2 0.5 9 0.6
Disease
Yes 117 19.6 80 23.7 46 29.1 157 37.8 400 26.5 < 0.001
No 481 80.4 257 76.3 112 70.9 258 62.2 1108 73.5
Place of residence
Mexico City 278 48.7 149 47.2 67 46.5 194 49.1 688 48.2 0.173
State of Mexico 95 16.6 54 17.1 39 27.1 77 19.5 265 18.6
Another state 198 34.7 113 35.8 38 26.4 124 31.4 473 33.2
Health insurance
Yes 421 70.4 232 68.8 113 71.5 269 64.8 1035 68.6 0.100
No 177 29.6 105 31.2 45 28.5 146 35.2 473 31.4
Prior mental health care
Yes 296 49.5 224 66.5 106 67.1 303 73 929 61.6 < 0.001
No 302 50.5 113 33.5 52 32.9 112 27 579 38.4

PHQ-9 = Patient Health Questionnaire-9.

It should be noted that there may be variability in each country’s data, since the survey was conducted at different times according to the epidemiological phase of each nation. However, 88.4 % of participants considered that they will experience negative repercussions in their individual economy.

A positive, middle-magnitude and statistically significant correlation was identified (Pearson’s r = 0.721, p < 0.001), between the levels of depression and anxiety symptoms.

Discussion

The main strategies to fight coronavirus COVID-19 transmission involve self-care behaviors, which should be approached from a psychological perspective, since they require modification or implementation of behaviors in people who apparently have no immediate reinforcing mechanisms, which complicates their execution.

Higher levels of anxiety and depression were identified than those reported in the SARS and influenza pandemics, which denotes a larger effect on general population mental health. Belonging to the female gender, not having children, a single marital status, medical comorbidity and a history of mental health care coincided with the variables indicated in the literature as being related to the presence of greater psychological symptoms; in addition, economic concerns, repercussions of the pandemic on daily life and academic backlog were identified.1 The presence of a medical condition was reported by 26.5 % of the sample, mainly of a cardiometabolic nature, which means that this group is at higher risk of becoming seriously ill with COVID-1914, and during the pandemic it might face difficulties for obtaining adequate treatment.9

One possible explanation for high levels of anxiety and depression is high exposure to information about COVID-19, which Avittey associates with constant exposure to overwhelming news headlines and misinformation.15

A need for general information about the health institutions people can resort to was identified, as well as concern about the effects of the COVID-19 pandemic on the economy. Family income instability or decrease has been identified as a significant factor in anxiety during the crisis.16

Even though acceptable adherence to health recommendations was recorded in the present study, 5.8 % did not stay away from meetings, 7.4 % did not keep appropriate distance from people and 9.8 % continued to leave home, a situation that entails repercussions on public health, since dissemination and transmission of the virus increases inasmuch as confinement and social distancing strategies are not followed.

Finally, although adequate psychological strategies to cope with the COVID-19 pandemic were identified, half the participants did not have such tools or conditions to adapt to the situation; therefore, it is necessary to focus on the population particular needs and cover them to help improve coping strategies. Receiving mental health care was considered necessary by 24 % of participants; however, 72 % did not have any remote care service, either by phone or online.

It is relevant to consider recommendations such as those reported by Li,9 who claims that the population exposed to COVID-19 can be classified in four levels:

  • 1. People who are more vulnerable to mental health problems, such as hospitalized patients with confirmed infection or serious physical condition, frontline health professionals, and administrative personnel.

  • 2. Isolated patients and in clinics with atypical infection symptoms.

  • 3. Individuals with level 1 and 2 contacts, i.e., family members, colleagues, friends, and rescue workers.

  • 4. People affected by epidemic prevention and control measures, susceptible people and the general population.

Among the limitations, it should be noted that the sample was collected by convenience and that a cross-sectional research design was used; therefore, making a prospective follow-up is suggested, which will allow changes in symptoms and safety measures to be observed as the public health situation is modified.

Conclusions

Mental health problems in the general population during the COVID-19 pandemic represent a challenge for the public health system; therefore valid and reliable psychosocial interventions are required to timely identify the onset and intensity of symptoms of depression and anxiety, as well as to assess the effects of clinical and community psychosocial interventions.

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FundingThe authors did not receive any sponsoring to carry out this article.

Ethical disclosure

Protection of people and animals. The authors declare that no experiments were performed on humans or animals for this research.

Confidentiality of data. The authors declare that they have followed the protocols of their work center on the publication of patient data.

Right to privacy and informed consent. The authors obtained informed consent from the participants referred to in the article. This document is in the possession of the corresponding author.

* Mendoza-Contreras L, Flores-Juárez J, Núñez-Hernández J, Guzmán Saldaña R, Lerma A. Galindo-Vázquez O. Propiedades psicométricas del Cuestionario sobre la Salud del Paciente (PHQ-9) y de la Escala del Trastorno de Ansiedad Generalizada (GAD-7) en población general mexicana. México: Servicio de Psicooncología, Instituto Nacional de Cancerología; 2020.

Unpublished document.

Received: May 07, 2020; Accepted: June 22, 2020

* Correspondence: Oscar Galindo-Vázquez E-mail: psigalindo@yahoo.com.mx

Conflict of interests

The authors declare that they have no conflicts of interest.

Creative Commons License Instituto Nacional de Cardiología Ignacio Chávez. Published by Permanyer. This is an open ccess article under the CC BY-NC-ND license