Background:

Several authors have identified factors associated with severe cases and death due to COVID-19; these include age, sex, comorbidities, and various elevated inflammatory markers such as D-dimer, C-reactive protein (CRP), and interleukin 6.

Objective:

To identify prognostic factors associated with severity and death in hospitalized subjects with COVID-19 pneumonia.

Methods:

Cross-sectional, analytical, prospective study, based on 111 patients admitted with a diagnosis of COVID-19 pneumonia, with oximetry higher than 70% and less than 90%. Multivariate discriminant analysis was an “outcome”, the dependent variable was the “outcome” (death or hospital discharge); the model was calculated using the stepwise inclusion method with five independent variables: age, C-reactive protein, ferritin, oximetry on admission and comorbidities.

Results:

111 subjects with a diagnosis of COVID-19 pneumonia were studied. Of these, 59 (53.15%) were diabetic, of whom 42 (71%) presented complications. There were two statistically significant variables in the comparison of averages according to outcome: C-reactive protein values (p<0.000) and oximetry at hospital admission (p=0.048).

Conclusions:

Increased C-reactive protein between the fourth and seventh day of hospitalization, and admission oximetry below 80% were associated with in-hospital mortality in 71% of cases.

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