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Revista mexicana de oftalmología

On-line version ISSN 2604-1227Print version ISSN 0187-4519


PAULO, José D.; GOMEZ-SUAREZ, Isabel C.  and  MONTOYA-CARRASQUILLA, Diana C.. Nodular scleritis caused by neurosyphilis in an immunocompetent patient. Case report. Rev. mex. oftalmol [online]. 2021, vol.95, n.4, pp.171-174.  Epub July 30, 2021. ISSN 2604-1227.

Case report:

A 59-year-old woman with nodular scleritis without improvement after oral treatment with non-steroidal anti-inflammatory drugs, and oral and topical corticosteroids. Tests were performed finding reactive VDRL in 32 dls and reactive FTA-ABS. A lumbar puncture evidenced pleocytosis. Nodular scleritis secondary to neurosyphilis was diagnosed and treatment with intravenous penicillin was initiated, showing improvement of scleral inflammation.


Scleritis due to syphilis is uncommon, and even more so if it is the only ocular manifestation. In addition, most reports of scleritis as a manifestation of syphilis have been described in people with HIV infection, but our patient was not immunocompromised, and HIV serology was negative.

Keywords : Sclera; Syphilis; Scleral diseases; Uveitis; Ocular inflammation.

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