Resumen

SMITH-PELLEGRIN, Dennise L. et al. Naltrexone, a therapeutic alternative in Darier disease. Rev. med. Hosp. Gen. Méx. [online]. 2021, vol.84, n.4, pp.177-180.  Epub 07-Mar-2022. ISSN 2524-177X.  https://doi.org/10.24875/hgmx.21000039.

Darier disease is a clinically variable rare disease with autosomal dominant inheritance caused by mutations in ATP2A2 gene. It affects skin, mucous membranes, and nails. The onset of symptoms is during adolescence and persists through adulthood, affecting quality of life. It presents papules and small malodorous keratotic yellow to brown plaques that emerge predominantly in seborrheic areas. In the present study, we describe a patient with Darier disease successfully treated with naltrexone at low doses.

Palabras llave : Darier disease; Naltrexone; Darier disease treatment; ATP2A2.

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